Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 1094543..1095219 Replicon chromosome
Accession NZ_CP009885
Organism Xylella fastidiosa strain Hib4

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag XFHB_RS05250 Protein ID WP_088577928.1
Coordinates 1094794..1095219 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag XFHB_RS05245 Protein ID WP_088577927.1
Coordinates 1094543..1094797 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XFHB_RS14190 1089979..1090785 + 807 WP_157293241.1 hypothetical protein -
XFHB_RS14195 1090808..1091044 + 237 WP_157293242.1 hypothetical protein -
XFHB_RS05210 1091127..1091399 + 273 WP_088577921.1 DUF1778 domain-containing protein -
XFHB_RS05215 1091396..1091881 + 486 WP_088577922.1 GNAT family N-acetyltransferase -
XFHB_RS05220 1092135..1092320 + 186 WP_088577923.1 hypothetical protein -
XFHB_RS05225 1092333..1092704 - 372 WP_157293243.1 hypothetical protein -
XFHB_RS05235 1093314..1093907 + 594 WP_088577926.1 hypothetical protein -
XFHB_RS05240 1093975..1094289 + 315 WP_060871452.1 hypothetical protein -
XFHB_RS05245 1094543..1094797 + 255 WP_088577927.1 plasmid stability protein stbC Antitoxin
XFHB_RS05250 1094794..1095219 + 426 WP_088577928.1 type II toxin-antitoxin system VapC family toxin Toxin
XFHB_RS14200 1095309..1095488 - 180 Protein_955 hypothetical protein -
XFHB_RS05255 1095487..1095852 - 366 Protein_956 conjugal transfer protein TrbJ -
XFHB_RS05260 1095958..1096323 - 366 WP_088577929.1 hypothetical protein -
XFHB_RS05265 1096373..1097002 - 630 WP_088577930.1 hypothetical protein -
XFHB_RS14205 1097236..1097403 - 168 WP_157293244.1 hypothetical protein -
XFHB_RS05270 1097492..1097731 + 240 WP_088577931.1 ribbon-helix-helix domain-containing protein -
XFHB_RS05275 1097731..1098150 + 420 WP_088577932.1 putative toxin-antitoxin system toxin component, PIN family -
XFHB_RS05280 1098235..1098519 + 285 WP_088577933.1 transcriptional regulator -
XFHB_RS05285 1098492..1098857 + 366 WP_088577934.1 antirestriction protein -
XFHB_RS05290 1099124..1099381 + 258 WP_057683510.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15273.81 Da        Isoelectric Point: 5.7092

>T50117 WP_088577928.1 NZ_CP009885:1094794-1095219 [Xylella fastidiosa]
MILLDTNVVSEPLRYTPDVRIIAWIDAQPLETLYLSAMTVAELRSGVALLPIGKRREALHEDLEKNVLPMFVGRVLPFDF
ACTNAYAELLAKVRKAGRSIQTADACIAAIALANGFTVATRDTSPFQAAGLIVIDPIGPSH

Download         Length: 426 bp

>T50117 NZ_CP009885:1094794-1095219 [Xylella fastidiosa]
ATGATCCTGCTCGATACGAACGTAGTTTCTGAGCCACTACGTTATACGCCGGATGTCCGCATCATTGCATGGATCGACGC
ACAACCCCTGGAGACGCTCTACCTGTCCGCAATGACTGTAGCTGAGTTGCGCTCCGGCGTGGCGCTACTACCAATTGGTA
AACGCCGTGAAGCGTTGCATGAGGACCTGGAAAAGAACGTGTTGCCCATGTTCGTTGGACGCGTGCTGCCGTTCGACTTC
GCTTGCACGAATGCTTATGCTGAGTTACTAGCGAAGGTTCGCAAGGCGGGCAGAAGTATCCAGACTGCTGACGCTTGCAT
TGCAGCAATCGCATTAGCCAACGGATTTACTGTTGCCACACGCGACACAAGCCCTTTCCAAGCTGCTGGCCTGATTGTCA
TCGACCCTATTGGCCCTTCCCACTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9313.62 Da        Isoelectric Point: 7.3221

>AT50117 WP_088577927.1 NZ_CP009885:1094543-1094797 [Xylella fastidiosa]
MANVHVRNLPDAVHRALRVRAAHNGRSTEAEIREILEVAVRPPERVKLGSLLAEIGQKVKLTDEEFAIFESVRDRTPAGA
ASFE

Download         Length: 255 bp

>AT50117 NZ_CP009885:1094543-1094797 [Xylella fastidiosa]
ATGGCAAACGTACATGTAAGAAATCTACCTGATGCCGTGCATCGCGCGCTTCGCGTGCGTGCCGCCCATAATGGCCGTAG
TACCGAGGCAGAAATCCGCGAAATCCTGGAGGTCGCTGTGCGACCGCCCGAGCGTGTCAAGTTGGGTTCGCTTCTGGCCG
AGATCGGCCAGAAGGTCAAGCTGACCGACGAAGAGTTCGCTATCTTTGAGAGCGTGCGCGATAGAACACCTGCCGGTGCA
GCGAGCTTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References