Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 1091127..1091881 Replicon chromosome
Accession NZ_CP009885
Organism Xylella fastidiosa strain Hib4

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag XFHB_RS05215 Protein ID WP_088577922.1
Coordinates 1091396..1091881 (+) Length 162 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag XFHB_RS05210 Protein ID WP_088577921.1
Coordinates 1091127..1091399 (+) Length 91 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XFHB_RS05165 1086551..1086811 + 261 WP_023906425.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
XFHB_RS05170 1086798..1087079 + 282 WP_023906426.1 type II toxin-antitoxin system YafQ family toxin -
XFHB_RS05180 1087476..1088510 - 1035 WP_023906427.1 serine protease -
XFHB_RS05185 1088675..1088761 - 87 Protein_942 transposase -
XFHB_RS05190 1089248..1089499 + 252 WP_010894487.1 antitoxin -
XFHB_RS05195 1089496..1089804 + 309 WP_010894488.1 type II toxin-antitoxin system RelE/ParE family toxin -
XFHB_RS14190 1089979..1090785 + 807 WP_157293241.1 hypothetical protein -
XFHB_RS14195 1090808..1091044 + 237 WP_157293242.1 hypothetical protein -
XFHB_RS05210 1091127..1091399 + 273 WP_088577921.1 DUF1778 domain-containing protein Antitoxin
XFHB_RS05215 1091396..1091881 + 486 WP_088577922.1 GNAT family N-acetyltransferase Toxin
XFHB_RS05220 1092135..1092320 + 186 WP_088577923.1 hypothetical protein -
XFHB_RS05225 1092333..1092704 - 372 WP_157293243.1 hypothetical protein -
XFHB_RS05235 1093314..1093907 + 594 WP_088577926.1 hypothetical protein -
XFHB_RS05240 1093975..1094289 + 315 WP_060871452.1 hypothetical protein -
XFHB_RS05245 1094543..1094797 + 255 WP_088577927.1 plasmid stability protein stbC -
XFHB_RS05250 1094794..1095219 + 426 WP_088577928.1 type II toxin-antitoxin system VapC family toxin -
XFHB_RS14200 1095309..1095488 - 180 Protein_955 hypothetical protein -
XFHB_RS05255 1095487..1095852 - 366 Protein_956 conjugal transfer protein TrbJ -
XFHB_RS05260 1095958..1096323 - 366 WP_088577929.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(32-148)

Antitoxin

(3-85)


Sequences


Toxin        


Download         Length: 162 a.a.        Molecular weight: 17817.56 Da        Isoelectric Point: 9.7126

>T50116 WP_088577922.1 NZ_CP009885:1091396-1091881 [Xylella fastidiosa]
VNMQISTPHSLTAAHRLDEFNCGEPSLDDWLKRRALTNHLNGASRTFVVVDANQYVLGYYALAAGSVAHQEATRAIRGNM
PDPVPVMVLGRLAVDTRAQGIRLGAALLKDTVTRVQSIAENVGVRALVVHALNERAKQFYEYYGFRASPMHLMTLMLPIK
F

Download         Length: 486 bp

>T50116 NZ_CP009885:1091396-1091881 [Xylella fastidiosa]
GTGAATATGCAGATTTCGACACCTCATTCACTCACGGCAGCGCATCGACTCGATGAATTCAATTGCGGTGAGCCATCGCT
GGATGATTGGCTTAAACGACGCGCATTGACCAACCATTTAAACGGGGCCAGCCGGACCTTCGTTGTTGTCGATGCCAACC
AGTACGTGCTTGGGTACTACGCTTTGGCAGCTGGGTCTGTCGCGCATCAAGAGGCCACGCGTGCTATCCGAGGTAATATG
CCTGATCCAGTGCCGGTCATGGTGCTCGGAAGGCTGGCTGTGGATACTCGCGCTCAAGGCATCAGACTCGGTGCGGCCTT
GCTTAAAGATACGGTAACTCGTGTACAGTCCATTGCAGAGAACGTCGGCGTCAGGGCATTGGTAGTGCATGCGTTGAACG
AGCGCGCAAAGCAATTCTACGAGTACTATGGTTTTCGAGCGTCACCAATGCACCTGATGACCTTGATGCTTCCGATTAAA
TTCTAG

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10281.79 Da        Isoelectric Point: 4.7419

>AT50116 WP_088577921.1 NZ_CP009885:1091127-1091399 [Xylella fastidiosa]
MRDASINLRAMPEQRDLIDQAANLLGKNRSDFMLEAACERAKAIILDQVFFNLDEERFRQFTVLLDAPQDTNLGLNRLMA
IKAPWSISNT

Download         Length: 273 bp

>AT50116 NZ_CP009885:1091127-1091399 [Xylella fastidiosa]
ATGCGCGACGCTTCCATCAACTTACGTGCCATGCCTGAGCAGCGCGACTTGATTGACCAGGCTGCTAATCTATTAGGCAA
GAATCGCTCAGACTTCATGCTAGAAGCTGCGTGCGAGCGTGCGAAAGCAATTATCCTGGATCAAGTCTTTTTTAATCTGG
ACGAAGAGAGGTTCCGGCAATTCACTGTGTTGCTTGATGCGCCACAAGACACCAATCTCGGCCTTAATCGCCTGATGGCA
ATTAAGGCTCCGTGGAGCATCAGCAATACGTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References