Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1276004..1276539 Replicon chromosome
Accession NZ_CP009838
Organism Yersinia enterocolitica strain 2516-87

Toxin (Protein)


Gene name relE Uniprot ID A0A7U7FI46
Locus tag CH48_RS05975 Protein ID WP_005156226.1
Coordinates 1276004..1276291 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7U7FI63
Locus tag CH48_RS05980 Protein ID WP_005156229.1
Coordinates 1276288..1276539 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CH48_RS05945 1271263..1272069 + 807 WP_013649159.1 phosphonate C-P lyase system protein PhnK -
CH48_RS05950 1272083..1272817 + 735 WP_032904377.1 phosphonate C-P lyase system protein PhnL -
CH48_RS05955 1272814..1273962 + 1149 WP_005156213.1 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase -
CH48_RS05960 1273962..1274540 + 579 WP_013649157.1 ribose 1,5-bisphosphokinase -
CH48_RS05965 1274531..1275298 + 768 WP_005156220.1 phosphonate metabolism protein PhnP -
CH48_RS05970 1275299..1275928 - 630 WP_005175332.1 hypothetical protein -
CH48_RS05975 1276004..1276291 - 288 WP_005156226.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CH48_RS05980 1276288..1276539 - 252 WP_005156229.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CH48_RS05985 1276747..1277199 - 453 WP_005181269.1 YhbP family protein -
CH48_RS05990 1277273..1278439 - 1167 WP_013649156.1 alginate lyase family protein -
CH48_RS05995 1278453..1279568 - 1116 WP_032904379.1 ABC transporter ATP-binding protein -
CH48_RS06000 1279580..1280419 - 840 WP_005156238.1 carbohydrate ABC transporter permease -
CH48_RS06005 1280438..1281322 - 885 WP_005156239.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11002.07 Da        Isoelectric Point: 10.3544

>T49929 WP_005156226.1 NZ_CP009838:c1276291-1276004 [Yersinia enterocolitica]
MIYKVKFRSDALKEWGKIDKVIQQQFAKKLKKCCENPHIPSAKLRGLSDCYKIKLRASGFRLVYQVIEDCLVIAVVAVGK
RERSDVYNLASERLR

Download         Length: 288 bp

>T49929 NZ_CP009838:c1276291-1276004 [Yersinia enterocolitica]
ATGATTTATAAAGTAAAATTTAGAAGTGATGCCCTAAAGGAATGGGGAAAGATAGACAAAGTTATTCAACAGCAGTTTGC
TAAAAAACTCAAAAAATGTTGTGAAAATCCTCATATTCCATCAGCAAAATTACGCGGATTATCAGACTGCTATAAAATAA
AATTACGGGCATCTGGTTTTAGGTTAGTTTATCAAGTTATTGAAGATTGTTTAGTTATCGCCGTGGTTGCCGTCGGCAAA
CGCGAACGCAGTGATGTTTATAACCTCGCCAGTGAACGGTTACGATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9270.65 Da        Isoelectric Point: 4.2264

>AT49929 WP_005156229.1 NZ_CP009838:c1276539-1276288 [Yersinia enterocolitica]
MANIILSDTSASVSELKKNPMATVKAGAGYPVAILNRNQPAFYCIPAELYERMLDALDDQELIRLVTERESQPLIDVDLD
KYL

Download         Length: 252 bp

>AT49929 NZ_CP009838:c1276539-1276288 [Yersinia enterocolitica]
ATGGCTAACATAATTTTAAGTGATACGAGCGCAAGTGTCAGCGAGTTAAAGAAAAACCCTATGGCCACAGTCAAAGCGGG
GGCGGGCTATCCAGTGGCTATTTTGAATAGAAACCAACCGGCATTTTATTGTATCCCCGCAGAATTATACGAGAGAATGC
TAGATGCCCTTGATGATCAAGAGCTTATCAGATTAGTTACCGAACGAGAGAGTCAGCCACTCATTGATGTAGATCTGGAT
AAGTATCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7U7FI46

Antitoxin

Source ID Structure
AlphaFold DB A0A7U7FI63

References