Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | FicTA/Fic(toxin) |
| Location | 2136304..2137100 | Replicon | chromosome |
| Accession | NZ_CP009826 | ||
| Organism | Xylella fastidiosa strain Pr8x | ||
Toxin (Protein)
| Gene name | VbhT | Uniprot ID | - |
| Locus tag | XFPR_RS09825 | Protein ID | WP_023907999.1 |
| Coordinates | 2136304..2136915 (-) | Length | 204 a.a. |
Antitoxin (Protein)
| Gene name | VbhA | Uniprot ID | A0A060HF63 |
| Locus tag | XFPR_RS09830 | Protein ID | WP_004087046.1 |
| Coordinates | 2136912..2137100 (-) | Length | 63 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| XFPR_RS09780 | 2131696..2131986 | - | 291 | WP_023907990.1 | hypothetical protein | - |
| XFPR_RS09785 | 2132107..2133219 | - | 1113 | WP_031336988.1 | Bro-N domain-containing protein | - |
| XFPR_RS09790 | 2133422..2133805 | - | 384 | WP_023907991.1 | hypothetical protein | - |
| XFPR_RS09795 | 2133802..2134050 | - | 249 | WP_031336990.1 | hypothetical protein | - |
| XFPR_RS09800 | 2134047..2134235 | - | 189 | WP_023907993.1 | hypothetical protein | - |
| XFPR_RS09805 | 2134296..2134577 | - | 282 | WP_023907994.1 | hypothetical protein | - |
| XFPR_RS09810 | 2134679..2135050 | + | 372 | WP_023907996.1 | hypothetical protein | - |
| XFPR_RS09815 | 2135230..2135475 | - | 246 | WP_023907997.1 | hypothetical protein | - |
| XFPR_RS09820 | 2135474..2136253 | + | 780 | WP_023907998.1 | helix-turn-helix transcriptional regulator | - |
| XFPR_RS09825 | 2136304..2136915 | - | 612 | WP_023907999.1 | Fic/DOC family protein | Toxin |
| XFPR_RS09830 | 2136912..2137100 | - | 189 | WP_004087046.1 | antitoxin VbhA family protein | Antitoxin |
| XFPR_RS09835 | 2137502..2137906 | + | 405 | Protein_1923 | hypothetical protein | - |
| XFPR_RS09840 | 2138227..2138685 | + | 459 | WP_023908001.1 | hypothetical protein | - |
| XFPR_RS09845 | 2138685..2139086 | + | 402 | WP_023908002.1 | hypothetical protein | - |
| XFPR_RS09850 | 2139083..2139274 | + | 192 | WP_023908003.1 | hypothetical protein | - |
| XFPR_RS09855 | 2139318..2139845 | + | 528 | WP_075584676.1 | hypothetical protein | - |
| XFPR_RS09860 | 2139964..2140155 | + | 192 | WP_023908006.1 | hypothetical protein | - |
| XFPR_RS09865 | 2140176..2140550 | + | 375 | WP_023908007.1 | hypothetical protein | - |
| XFPR_RS09870 | 2140570..2141391 | + | 822 | WP_023908008.1 | YfdQ family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2102564..2167206 | 64642 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 204 a.a. Molecular weight: 22919.68 Da Isoelectric Point: 4.9434
>T49894 WP_023907999.1 NZ_CP009826:c2136915-2136304 [Xylella fastidiosa]
MKYAGDRGDPYLDSETGVLRNLLGIRDQGWLDKIESTLSFLRTSELRERPVKGKFDLAHLQEIHNRLFQDVYDWAGQIRQ
VEISKGNTMFAQQIAIQSAAQQIFGQLAKEQFLCGLDAEEFSKRAGDYLGEINVLHPFREGNGRTQREFIAQLAQRAGYR
IDWGVVSQADMIKASIDAYNGDSSGLASIIRDGISDQLFKDNE
MKYAGDRGDPYLDSETGVLRNLLGIRDQGWLDKIESTLSFLRTSELRERPVKGKFDLAHLQEIHNRLFQDVYDWAGQIRQ
VEISKGNTMFAQQIAIQSAAQQIFGQLAKEQFLCGLDAEEFSKRAGDYLGEINVLHPFREGNGRTQREFIAQLAQRAGYR
IDWGVVSQADMIKASIDAYNGDSSGLASIIRDGISDQLFKDNE
Download Length: 612 bp
>T49894 NZ_CP009826:c2136915-2136304 [Xylella fastidiosa]
ATGAAATACGCAGGGGATCGTGGTGATCCTTACCTGGACAGCGAAACAGGTGTTCTTCGTAATCTCCTTGGAATCAGGGA
TCAGGGGTGGCTCGATAAAATAGAGTCCACCCTTTCTTTTTTGCGAACCAGCGAATTGCGTGAGCGACCCGTAAAAGGCA
AATTTGATCTAGCGCATTTACAGGAAATCCATAATCGCCTTTTCCAGGATGTGTACGACTGGGCGGGTCAAATCCGTCAA
GTTGAAATCTCGAAAGGCAACACGATGTTTGCCCAGCAGATTGCGATTCAGAGTGCGGCGCAGCAGATCTTTGGGCAGCT
TGCTAAAGAGCAATTTTTGTGTGGCCTTGATGCTGAGGAATTCAGCAAACGGGCAGGTGATTATCTTGGTGAAATTAATG
TGCTTCACCCATTCCGCGAGGGAAATGGCAGGACGCAACGGGAATTCATCGCGCAATTGGCTCAGCGTGCAGGTTACAGG
ATCGACTGGGGCGTGGTCAGCCAGGCGGATATGATTAAAGCGTCAATCGACGCTTACAACGGGGATTCAAGCGGATTGGC
TAGTATCATCCGCGATGGAATATCTGATCAGCTTTTTAAAGATAATGAGTAA
ATGAAATACGCAGGGGATCGTGGTGATCCTTACCTGGACAGCGAAACAGGTGTTCTTCGTAATCTCCTTGGAATCAGGGA
TCAGGGGTGGCTCGATAAAATAGAGTCCACCCTTTCTTTTTTGCGAACCAGCGAATTGCGTGAGCGACCCGTAAAAGGCA
AATTTGATCTAGCGCATTTACAGGAAATCCATAATCGCCTTTTCCAGGATGTGTACGACTGGGCGGGTCAAATCCGTCAA
GTTGAAATCTCGAAAGGCAACACGATGTTTGCCCAGCAGATTGCGATTCAGAGTGCGGCGCAGCAGATCTTTGGGCAGCT
TGCTAAAGAGCAATTTTTGTGTGGCCTTGATGCTGAGGAATTCAGCAAACGGGCAGGTGATTATCTTGGTGAAATTAATG
TGCTTCACCCATTCCGCGAGGGAAATGGCAGGACGCAACGGGAATTCATCGCGCAATTGGCTCAGCGTGCAGGTTACAGG
ATCGACTGGGGCGTGGTCAGCCAGGCGGATATGATTAAAGCGTCAATCGACGCTTACAACGGGGATTCAAGCGGATTGGC
TAGTATCATCCGCGATGGAATATCTGATCAGCTTTTTAAAGATAATGAGTAA
Antitoxin
Download Length: 63 a.a. Molecular weight: 6855.80 Da Isoelectric Point: 4.9859
>AT49894 WP_004087046.1 NZ_CP009826:c2137100-2136912 [Xylella fastidiosa]
MLTDHEKAERRAVVQSALASQRIEGLEPDAQAVVDAECWARGEMTIAAAVDQYKARVRLQMA
MLTDHEKAERRAVVQSALASQRIEGLEPDAQAVVDAECWARGEMTIAAAVDQYKARVRLQMA
Download Length: 189 bp
>AT49894 NZ_CP009826:c2137100-2136912 [Xylella fastidiosa]
ATGCTGACAGATCATGAGAAAGCTGAACGCCGTGCTGTGGTGCAAAGCGCACTCGCAAGCCAACGCATTGAGGGGTTAGA
GCCGGATGCGCAGGCCGTGGTTGATGCTGAATGCTGGGCGCGTGGTGAAATGACTATCGCTGCCGCCGTGGACCAGTACA
AAGCGCGTGTTCGGCTCCAGATGGCATGA
ATGCTGACAGATCATGAGAAAGCTGAACGCCGTGCTGTGGTGCAAAGCGCACTCGCAAGCCAACGCATTGAGGGGTTAGA
GCCGGATGCGCAGGCCGTGGTTGATGCTGAATGCTGGGCGCGTGGTGAAATGACTATCGCTGCCGCCGTGGACCAGTACA
AAGCGCGTGTTCGGCTCCAGATGGCATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|