Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relB-parE/ParE-RHH |
Location | 1043261..1043823 | Replicon | chromosome |
Accession | NZ_CP009826 | ||
Organism | Xylella fastidiosa strain Pr8x |
Toxin (Protein)
Gene name | parE | Uniprot ID | Q9PBR6 |
Locus tag | XFPR_RS04525 | Protein ID | WP_010894527.1 |
Coordinates | 1043527..1043823 (+) | Length | 99 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | Q9PBR5 |
Locus tag | XFPR_RS04520 | Protein ID | WP_010894528.1 |
Coordinates | 1043261..1043539 (+) | Length | 93 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
XFPR_RS04490 | 1039355..1040161 | + | 807 | WP_023907555.1 | oxidoreductase | - |
XFPR_RS04495 | 1040491..1040751 | + | 261 | WP_010894534.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | - |
XFPR_RS04500 | 1040738..1041019 | + | 282 | WP_023907556.1 | type II toxin-antitoxin system YafQ family toxin | - |
XFPR_RS04505 | 1041437..1041799 | - | 363 | WP_143704175.1 | hypothetical protein | - |
XFPR_RS04510 | 1041819..1042478 | - | 660 | WP_023907557.1 | hypothetical protein | - |
XFPR_RS04515 | 1042484..1042732 | - | 249 | WP_196432191.1 | transposase | - |
XFPR_RS04520 | 1043261..1043539 | + | 279 | WP_010894528.1 | CopG family ribbon-helix-helix protein | Antitoxin |
XFPR_RS04525 | 1043527..1043823 | + | 297 | WP_010894527.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
XFPR_RS04530 | 1044480..1044722 | + | 243 | WP_010894524.1 | type II toxin-antitoxin system ParD family antitoxin | - |
XFPR_RS04535 | 1044715..1045003 | + | 289 | Protein_879 | type II toxin-antitoxin system RelE/ParE family toxin | - |
XFPR_RS04540 | 1045465..1045899 | + | 435 | Protein_880 | hypothetical protein | - |
XFPR_RS04545 | 1046308..1046763 | + | 456 | WP_010894521.1 | hypothetical protein | - |
XFPR_RS04550 | 1046760..1047032 | + | 273 | WP_010894520.1 | hypothetical protein | - |
XFPR_RS04555 | 1047036..1047344 | + | 309 | WP_010894519.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
XFPR_RS04560 | 1047453..1047722 | + | 270 | WP_010894518.1 | hypothetical protein | - |
XFPR_RS04565 | 1047774..1047977 | + | 204 | WP_023906434.1 | hypothetical protein | - |
XFPR_RS04570 | 1047971..1048506 | + | 536 | Protein_886 | recombinase family protein | - |
XFPR_RS04575 | 1048536..1048745 | - | 210 | WP_010894516.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 11155.72 Da Isoelectric Point: 7.4670
>T49890 WP_010894527.1 NZ_CP009826:1043527-1043823 [Xylella fastidiosa]
MPRVIFAPEAILNIQRLRNFLHPKNTDAARRAGEAIMRGARMLGAQPHIGRPVDDMPDEYREWLIDFGDSGYVARYHIDG
DTVTILAVRHHKEVGYTS
MPRVIFAPEAILNIQRLRNFLHPKNTDAARRAGEAIMRGARMLGAQPHIGRPVDDMPDEYREWLIDFGDSGYVARYHIDG
DTVTILAVRHHKEVGYTS
Download Length: 297 bp
>T49890 NZ_CP009826:1043527-1043823 [Xylella fastidiosa]
ATGCCACGGGTGATCTTCGCTCCCGAAGCCATCCTGAACATTCAACGATTGCGGAATTTCCTGCATCCGAAGAACACCGA
TGCCGCAAGGCGGGCCGGTGAAGCCATCATGCGGGGTGCGCGGATGCTTGGAGCGCAGCCACATATCGGTCGTCCGGTTG
ATGATATGCCCGATGAGTACAGGGAATGGCTGATTGACTTCGGAGATAGCGGTTATGTGGCCCGCTACCACATTGATGGC
GATACCGTCACGATCTTGGCTGTTCGACACCATAAGGAAGTGGGATACACCAGCTGA
ATGCCACGGGTGATCTTCGCTCCCGAAGCCATCCTGAACATTCAACGATTGCGGAATTTCCTGCATCCGAAGAACACCGA
TGCCGCAAGGCGGGCCGGTGAAGCCATCATGCGGGGTGCGCGGATGCTTGGAGCGCAGCCACATATCGGTCGTCCGGTTG
ATGATATGCCCGATGAGTACAGGGAATGGCTGATTGACTTCGGAGATAGCGGTTATGTGGCCCGCTACCACATTGATGGC
GATACCGTCACGATCTTGGCTGTTCGACACCATAAGGAAGTGGGATACACCAGCTGA
Antitoxin
Download Length: 93 a.a. Molecular weight: 10772.08 Da Isoelectric Point: 5.6126
>AT49890 WP_010894528.1 NZ_CP009826:1043261-1043539 [Xylella fastidiosa]
MGMATSIKLDDELKGRVQHLADVRRRTSHWIMREAIAQYVEREEKRETFRQDTLKAWEEFQATGLHVTTEEVEKWLSSWG
TENELSAPVCHG
MGMATSIKLDDELKGRVQHLADVRRRTSHWIMREAIAQYVEREEKRETFRQDTLKAWEEFQATGLHVTTEEVEKWLSSWG
TENELSAPVCHG
Download Length: 279 bp
>AT49890 NZ_CP009826:1043261-1043539 [Xylella fastidiosa]
ATGGGCATGGCAACCTCCATCAAGCTTGATGATGAGCTGAAAGGACGTGTGCAGCATCTGGCCGATGTTCGCCGCCGCAC
TTCGCACTGGATCATGCGCGAGGCGATCGCGCAGTACGTTGAGCGTGAGGAAAAGCGTGAGACGTTTCGGCAGGACACGC
TGAAGGCATGGGAAGAGTTTCAGGCGACCGGCCTGCACGTGACGACCGAAGAAGTCGAGAAGTGGCTTTCGAGTTGGGGC
ACTGAAAATGAATTGTCAGCGCCCGTATGCCACGGGTGA
ATGGGCATGGCAACCTCCATCAAGCTTGATGATGAGCTGAAAGGACGTGTGCAGCATCTGGCCGATGTTCGCCGCCGCAC
TTCGCACTGGATCATGCGCGAGGCGATCGCGCAGTACGTTGAGCGTGAGGAAAAGCGTGAGACGTTTCGGCAGGACACGC
TGAAGGCATGGGAAGAGTTTCAGGCGACCGGCCTGCACGTGACGACCGAAGAAGTCGAGAAGTGGCTTTCGAGTTGGGGC
ACTGAAAATGAATTGTCAGCGCCCGTATGCCACGGGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1S0VAK4 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1S0V821 |