Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/COG3657-DUF971
Location 859503..860107 Replicon chromosome
Accession NZ_CP009823
Organism Xylella fastidiosa strain J1a12

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag OY18_RS04140 Protein ID WP_060872108.1
Coordinates 859805..860107 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OY18_RS04135 Protein ID WP_060872107.1
Coordinates 859503..859808 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OY18_RS04085 855366..855542 + 177 WP_088569668.1 Blp family class II bacteriocin -
OY18_RS04090 855576..855764 + 189 WP_081089780.1 hypothetical protein -
OY18_RS04095 855769..855939 - 171 WP_081089781.1 antitoxin -
OY18_RS04100 (OY18_03825) 855992..856267 - 276 WP_060871810.1 type II toxin-antitoxin system RelE/ParE family toxin -
OY18_RS04105 (OY18_03830) 856251..856478 - 228 WP_031336679.1 DUF6290 family protein -
OY18_RS04110 (OY18_03835) 856591..857361 + 771 WP_088569669.1 hypothetical protein -
OY18_RS04115 (OY18_03840) 857361..857678 + 318 WP_069107095.1 hypothetical protein -
OY18_RS04120 (OY18_03845) 857675..858505 + 831 WP_060872216.1 hypothetical protein -
OY18_RS04125 (OY18_03850) 858502..859323 + 822 WP_229926333.1 Gp138 family membrane-puncturing spike protein -
OY18_RS14910 859307..859492 + 186 WP_229926334.1 hypothetical protein -
OY18_RS04135 (OY18_03860) 859503..859808 - 306 WP_060872107.1 putative addiction module antidote protein Antitoxin
OY18_RS04140 (OY18_03865) 859805..860107 - 303 WP_060872108.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OY18_RS04145 (OY18_03870) 860206..861351 + 1146 WP_060872109.1 baseplate J/gp47 family protein -
OY18_RS04150 (OY18_03875) 861348..861908 + 561 WP_010894176.1 DUF2612 domain-containing protein -
OY18_RS04155 (OY18_03880) 861912..863075 + 1164 WP_060872110.1 tail fiber protein -
OY18_RS04160 (OY18_03885) 863076..863303 - 228 WP_060872111.1 hypothetical protein -
OY18_RS04165 (OY18_03890) 863317..863940 - 624 WP_143704186.1 hypothetical protein -
OY18_RS04170 (OY18_03895) 863873..864421 - 549 WP_023907959.1 DUF4065 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 790250..953208 162958


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-85)

Antitoxin

Uncharacterized protein HI1420

(7-97)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11016.81 Da        Isoelectric Point: 9.6861

>T49875 WP_060872108.1 NZ_CP009823:c860107-859805 [Xylella fastidiosa]
MVELIKTSTFDAWINSLRDRKAAARIQARLDRLALGNPGDVKPVGAGISEMRIDHGPGYRIYFMKHGAVLILLLCGGDKS
SQVRDIEQAKALAALWKDEP

Download         Length: 303 bp

>T49875 NZ_CP009823:c860107-859805 [Xylella fastidiosa]
ATGGTCGAACTCATCAAAACCAGCACTTTTGATGCTTGGATAAACAGCTTACGTGACCGCAAAGCAGCCGCCAGAATTCA
AGCGCGTCTTGATCGGCTTGCACTTGGCAATCCCGGCGACGTGAAGCCTGTGGGTGCTGGCATCTCAGAAATGAGGATCG
ACCATGGGCCCGGATATCGGATCTATTTTATGAAGCATGGTGCAGTACTGATTCTCTTGCTTTGCGGTGGCGATAAATCG
TCACAAGTACGAGATATAGAGCAGGCTAAGGCACTGGCTGCACTGTGGAAGGATGAGCCATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11052.48 Da        Isoelectric Point: 6.3261

>AT49875 WP_060872107.1 NZ_CP009823:c859808-859503 [Xylella fastidiosa]
MNNETFSRYDTADYLKTEEDIAAYMEAVMEEGGRDNPAFIARALGAVARARNLSQLARDVGMSRQGLDKALSNDGNPSFS
TILKVAKALGLRMSFTPSSMR

Download         Length: 306 bp

>AT49875 NZ_CP009823:c859808-859503 [Xylella fastidiosa]
ATGAATAATGAGACGTTTAGTCGATACGACACCGCTGACTACCTCAAAACCGAAGAAGATATTGCGGCTTATATGGAAGC
CGTCATGGAAGAAGGTGGTAGGGATAATCCTGCTTTTATTGCACGGGCACTTGGTGCTGTCGCTCGTGCTCGTAATTTAA
GTCAGCTTGCTCGTGACGTTGGTATGTCCAGGCAAGGACTAGACAAGGCACTCTCTAACGACGGCAACCCAAGCTTCTCA
ACCATCTTAAAAGTGGCTAAGGCGCTTGGTTTACGGATGTCATTCACTCCTTCCTCTATGCGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References