Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PumA-relB/COG3657-DUF971 |
Location | 859503..860107 | Replicon | chromosome |
Accession | NZ_CP009823 | ||
Organism | Xylella fastidiosa strain J1a12 |
Toxin (Protein)
Gene name | PumA | Uniprot ID | - |
Locus tag | OY18_RS04140 | Protein ID | WP_060872108.1 |
Coordinates | 859805..860107 (-) | Length | 101 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | OY18_RS04135 | Protein ID | WP_060872107.1 |
Coordinates | 859503..859808 (-) | Length | 102 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
OY18_RS04085 | 855366..855542 | + | 177 | WP_088569668.1 | Blp family class II bacteriocin | - |
OY18_RS04090 | 855576..855764 | + | 189 | WP_081089780.1 | hypothetical protein | - |
OY18_RS04095 | 855769..855939 | - | 171 | WP_081089781.1 | antitoxin | - |
OY18_RS04100 (OY18_03825) | 855992..856267 | - | 276 | WP_060871810.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
OY18_RS04105 (OY18_03830) | 856251..856478 | - | 228 | WP_031336679.1 | DUF6290 family protein | - |
OY18_RS04110 (OY18_03835) | 856591..857361 | + | 771 | WP_088569669.1 | hypothetical protein | - |
OY18_RS04115 (OY18_03840) | 857361..857678 | + | 318 | WP_069107095.1 | hypothetical protein | - |
OY18_RS04120 (OY18_03845) | 857675..858505 | + | 831 | WP_060872216.1 | hypothetical protein | - |
OY18_RS04125 (OY18_03850) | 858502..859323 | + | 822 | WP_229926333.1 | Gp138 family membrane-puncturing spike protein | - |
OY18_RS14910 | 859307..859492 | + | 186 | WP_229926334.1 | hypothetical protein | - |
OY18_RS04135 (OY18_03860) | 859503..859808 | - | 306 | WP_060872107.1 | putative addiction module antidote protein | Antitoxin |
OY18_RS04140 (OY18_03865) | 859805..860107 | - | 303 | WP_060872108.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
OY18_RS04145 (OY18_03870) | 860206..861351 | + | 1146 | WP_060872109.1 | baseplate J/gp47 family protein | - |
OY18_RS04150 (OY18_03875) | 861348..861908 | + | 561 | WP_010894176.1 | DUF2612 domain-containing protein | - |
OY18_RS04155 (OY18_03880) | 861912..863075 | + | 1164 | WP_060872110.1 | tail fiber protein | - |
OY18_RS04160 (OY18_03885) | 863076..863303 | - | 228 | WP_060872111.1 | hypothetical protein | - |
OY18_RS04165 (OY18_03890) | 863317..863940 | - | 624 | WP_143704186.1 | hypothetical protein | - |
OY18_RS04170 (OY18_03895) | 863873..864421 | - | 549 | WP_023907959.1 | DUF4065 domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 790250..953208 | 162958 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 11016.81 Da Isoelectric Point: 9.6861
>T49875 WP_060872108.1 NZ_CP009823:c860107-859805 [Xylella fastidiosa]
MVELIKTSTFDAWINSLRDRKAAARIQARLDRLALGNPGDVKPVGAGISEMRIDHGPGYRIYFMKHGAVLILLLCGGDKS
SQVRDIEQAKALAALWKDEP
MVELIKTSTFDAWINSLRDRKAAARIQARLDRLALGNPGDVKPVGAGISEMRIDHGPGYRIYFMKHGAVLILLLCGGDKS
SQVRDIEQAKALAALWKDEP
Download Length: 303 bp
>T49875 NZ_CP009823:c860107-859805 [Xylella fastidiosa]
ATGGTCGAACTCATCAAAACCAGCACTTTTGATGCTTGGATAAACAGCTTACGTGACCGCAAAGCAGCCGCCAGAATTCA
AGCGCGTCTTGATCGGCTTGCACTTGGCAATCCCGGCGACGTGAAGCCTGTGGGTGCTGGCATCTCAGAAATGAGGATCG
ACCATGGGCCCGGATATCGGATCTATTTTATGAAGCATGGTGCAGTACTGATTCTCTTGCTTTGCGGTGGCGATAAATCG
TCACAAGTACGAGATATAGAGCAGGCTAAGGCACTGGCTGCACTGTGGAAGGATGAGCCATGA
ATGGTCGAACTCATCAAAACCAGCACTTTTGATGCTTGGATAAACAGCTTACGTGACCGCAAAGCAGCCGCCAGAATTCA
AGCGCGTCTTGATCGGCTTGCACTTGGCAATCCCGGCGACGTGAAGCCTGTGGGTGCTGGCATCTCAGAAATGAGGATCG
ACCATGGGCCCGGATATCGGATCTATTTTATGAAGCATGGTGCAGTACTGATTCTCTTGCTTTGCGGTGGCGATAAATCG
TCACAAGTACGAGATATAGAGCAGGCTAAGGCACTGGCTGCACTGTGGAAGGATGAGCCATGA
Antitoxin
Download Length: 102 a.a. Molecular weight: 11052.48 Da Isoelectric Point: 6.3261
>AT49875 WP_060872107.1 NZ_CP009823:c859808-859503 [Xylella fastidiosa]
MNNETFSRYDTADYLKTEEDIAAYMEAVMEEGGRDNPAFIARALGAVARARNLSQLARDVGMSRQGLDKALSNDGNPSFS
TILKVAKALGLRMSFTPSSMR
MNNETFSRYDTADYLKTEEDIAAYMEAVMEEGGRDNPAFIARALGAVARARNLSQLARDVGMSRQGLDKALSNDGNPSFS
TILKVAKALGLRMSFTPSSMR
Download Length: 306 bp
>AT49875 NZ_CP009823:c859808-859503 [Xylella fastidiosa]
ATGAATAATGAGACGTTTAGTCGATACGACACCGCTGACTACCTCAAAACCGAAGAAGATATTGCGGCTTATATGGAAGC
CGTCATGGAAGAAGGTGGTAGGGATAATCCTGCTTTTATTGCACGGGCACTTGGTGCTGTCGCTCGTGCTCGTAATTTAA
GTCAGCTTGCTCGTGACGTTGGTATGTCCAGGCAAGGACTAGACAAGGCACTCTCTAACGACGGCAACCCAAGCTTCTCA
ACCATCTTAAAAGTGGCTAAGGCGCTTGGTTTACGGATGTCATTCACTCCTTCCTCTATGCGTTAA
ATGAATAATGAGACGTTTAGTCGATACGACACCGCTGACTACCTCAAAACCGAAGAAGATATTGCGGCTTATATGGAAGC
CGTCATGGAAGAAGGTGGTAGGGATAATCCTGCTTTTATTGCACGGGCACTTGGTGCTGTCGCTCGTGCTCGTAATTTAA
GTCAGCTTGCTCGTGACGTTGGTATGTCCAGGCAAGGACTAGACAAGGCACTCTCTAACGACGGCAACCCAAGCTTCTCA
ACCATCTTAAAAGTGGCTAAGGCGCTTGGTTTACGGATGTCATTCACTCCTTCCTCTATGCGTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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