Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PhRel2-ATphRel2/DUF4065(antitoxin)
Location 633464..634920 Replicon chromosome
Accession NZ_CP009796
Organism Bacillus subtilis strain SG6

Toxin (Protein)


Gene name phRel2 Uniprot ID -
Locus tag OB04_RS03490 Protein ID WP_038428495.1
Coordinates 633464..634165 (+) Length 234 a.a.

Antitoxin (Protein)


Gene name ATphRel2 Uniprot ID -
Locus tag OB04_RS03495 Protein ID WP_038428497.1
Coordinates 634171..634920 (+) Length 250 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OB04_RS03460 629896..630282 + 387 WP_038428488.1 hypothetical protein -
OB04_RS22150 630422..630589 + 168 WP_154231162.1 XkdX family protein -
OB04_RS03465 630603..630830 + 228 WP_038428489.1 hypothetical protein -
OB04_RS03470 630903..631172 + 270 WP_080348108.1 hemolysin XhlA family protein -
OB04_RS03475 631188..631451 + 264 WP_038428491.1 phage holin -
OB04_RS03480 631504..632325 + 822 WP_038428493.1 N-acetylmuramoyl-L-alanine amidase -
OB04_RS22415 632584..632727 + 144 WP_015715414.1 hypothetical protein -
OB04_RS03485 632975..633205 + 231 WP_038428494.1 DNA-binding protein -
OB04_RS03490 633464..634165 + 702 WP_038428495.1 hypothetical protein Toxin
OB04_RS03495 634171..634920 + 750 WP_038428497.1 DUF4065 domain-containing protein Antitoxin
OB04_RS03500 634950..635138 - 189 WP_038428499.1 hypothetical protein -
OB04_RS22155 636051..637046 + 996 WP_038428500.1 alpha/beta hydrolase family protein -
OB04_RS03510 637146..639635 - 2490 WP_038428501.1 glucitol operon transcriptional regulator GutR -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - groEL 584940..634920 49980


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin SocA-like, Panacea domain

(113-225)


Sequences

Toxin        


Download         Length: 234 a.a.        Molecular weight: 28016.74 Da        Isoelectric Point: 6.5777

>T49842 WP_038428495.1 NZ_CP009796:633464-634165 [Bacillus subtilis]
MIKCTCEIESFCNDLHELILEINQLHNDFSTEFSLNKDVKHFNLRKKQIRHITEVTEKKGLFSIDNDFFILLQHYAEKLE
NVVIYNDLEYLYSDFDLRLRVKQPDSIVNKLKYYRVGKLESGQIPLRKCLNDLLGMRITIDSFDHNNDCFQNICDLLMNQ
YRINCMDSSKGDYKAFHFYFYGESNTFFPWELQIWRTEDKEANNRSHQLHKQEYTNWASIYKNSTETSVEKKR

Download         Length: 702 bp

>T49842 NZ_CP009796:633464-634165 [Bacillus subtilis]
TTGATTAAATGCACTTGTGAAATCGAGTCATTTTGCAATGATCTTCATGAGTTGATACTAGAAATTAATCAGTTGCATAA
TGATTTTTCAACCGAATTCAGCTTAAATAAAGATGTAAAGCATTTTAACTTAAGAAAGAAACAAATAAGACATATTACAG
AGGTAACTGAAAAGAAGGGTCTTTTCTCAATCGATAATGATTTTTTTATTTTACTTCAACATTACGCTGAAAAACTAGAA
AATGTTGTCATCTATAATGACTTGGAGTATCTATATAGCGACTTTGACTTGCGCCTTAGAGTAAAACAACCAGATTCGAT
TGTCAATAAGCTAAAGTATTATCGTGTTGGAAAGCTCGAGAGCGGGCAAATACCTTTAAGAAAGTGCTTGAATGATTTGT
TGGGAATGAGAATAACAATTGATTCTTTTGACCATAATAATGACTGTTTTCAGAATATCTGTGACTTATTGATGAACCAA
TACAGAATAAATTGTATGGATTCATCAAAGGGTGATTATAAAGCATTTCATTTTTATTTTTATGGTGAAAGTAATACCTT
TTTTCCTTGGGAGCTTCAAATTTGGAGAACTGAAGATAAAGAAGCAAATAATCGATCTCACCAACTTCACAAACAAGAAT
ATACAAATTGGGCATCGATTTATAAAAACTCTACAGAAACATCTGTGGAGAAAAAGAGGTGA

Antitoxin


Download         Length: 250 a.a.        Molecular weight: 28913.17 Da        Isoelectric Point: 6.9679

>AT49842 WP_038428497.1 NZ_CP009796:634171-634920 [Bacillus subtilis]
MAFHFIAIISDFSGGRRIGWHYSSEERLDKNYISEFFERVKEKCGKVQFGIHKLSTDSTSWNSVTEKDSFFEDVIVTEDI
TSFIDVISKDKELTAYDVAKFVLSFQPSSHLKLQKLLYYIYAEFLLKTGKKLFREPIVAFKYGPVIEDIFFKYKRHGKSI
IDYREDANIKLLTDDLVVTPTFMKVLSSEHGLEAIECITKVLVKYGKHAPFRLVDMTHQEGGPWKRAYEPGQNCVITDEL
ITQYHQYAT

Download         Length: 750 bp

>AT49842 NZ_CP009796:634171-634920 [Bacillus subtilis]
ATGGCATTTCATTTTATCGCGATTATTAGTGATTTTTCTGGTGGTAGAAGAATTGGCTGGCACTATTCGAGCGAGGAAAG
ATTGGATAAAAACTACATTTCCGAATTCTTTGAAAGAGTTAAGGAAAAATGTGGTAAGGTTCAATTTGGAATTCACAAAT
TATCAACTGATTCAACTAGCTGGAATTCTGTCACTGAGAAAGATTCCTTTTTTGAGGATGTTATTGTGACAGAGGATATT
ACCTCCTTTATAGATGTAATATCAAAAGACAAGGAATTAACCGCATATGATGTGGCAAAATTTGTTTTGTCCTTTCAACC
ATCCTCACACTTAAAATTGCAAAAATTGTTATATTATATTTATGCTGAGTTTTTATTAAAAACGGGGAAAAAGCTATTCA
GAGAACCCATAGTAGCGTTTAAATATGGCCCTGTTATCGAGGATATTTTCTTTAAATATAAGAGACATGGGAAATCTATA
ATAGATTATCGAGAGGACGCTAACATAAAACTTCTTACTGATGATTTGGTGGTAACGCCGACATTCATGAAGGTTTTGTC
TTCTGAGCATGGACTAGAAGCTATAGAATGTATTACAAAAGTGCTTGTTAAATACGGAAAGCATGCACCTTTCCGTTTAG
TTGATATGACTCATCAAGAAGGTGGACCTTGGAAAAGAGCATACGAGCCAGGTCAAAATTGTGTAATAACAGATGAACTT
ATTACTCAGTATCACCAATATGCTACGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References