Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relB-parE/ParE-RHH |
Location | 1970165..1970727 | Replicon | chromosome |
Accession | NZ_CP009790 | ||
Organism | Xylella fastidiosa strain U24d |
Toxin (Protein)
Gene name | parE | Uniprot ID | Q9PBR6 |
Locus tag | XFUD_RS09645 | Protein ID | WP_010894527.1 |
Coordinates | 1970165..1970461 (-) | Length | 99 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | Q9PBR5 |
Locus tag | XFUD_RS09650 | Protein ID | WP_010894528.1 |
Coordinates | 1970449..1970727 (-) | Length | 93 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
XFUD_RS09590 | 1965243..1965452 | + | 210 | WP_010894516.1 | hypothetical protein | - |
XFUD_RS09595 | 1965482..1966017 | - | 536 | Protein_1747 | recombinase family protein | - |
XFUD_RS09600 | 1966011..1966214 | - | 204 | WP_023906434.1 | hypothetical protein | - |
XFUD_RS09605 | 1966266..1966535 | - | 270 | WP_010894518.1 | hypothetical protein | - |
XFUD_RS09610 | 1966644..1966952 | - | 309 | WP_010894519.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
XFUD_RS09615 | 1966956..1967228 | - | 273 | WP_010894520.1 | hypothetical protein | - |
XFUD_RS09620 | 1967225..1967680 | - | 456 | WP_010894521.1 | hypothetical protein | - |
XFUD_RS09625 | 1968089..1968523 | - | 435 | Protein_1753 | hypothetical protein | - |
XFUD_RS13730 | 1968573..1968830 | - | 258 | WP_140190226.1 | hypothetical protein | - |
XFUD_RS09630 | 1968985..1969273 | - | 289 | Protein_1755 | type II toxin-antitoxin system RelE/ParE family toxin | - |
XFUD_RS09635 | 1969266..1969508 | - | 243 | WP_010894524.1 | type II toxin-antitoxin system ParD family antitoxin | - |
XFUD_RS09645 | 1970165..1970461 | - | 297 | WP_010894527.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
XFUD_RS09650 | 1970449..1970727 | - | 279 | WP_010894528.1 | CopG family ribbon-helix-helix protein | Antitoxin |
XFUD_RS09655 | 1971259..1971345 | + | 87 | Protein_1759 | transposase | - |
XFUD_RS09660 | 1971510..1972169 | + | 660 | WP_010894530.1 | hypothetical protein | - |
XFUD_RS09665 | 1972150..1972551 | + | 402 | WP_010894531.1 | hypothetical protein | - |
XFUD_RS09675 | 1972969..1973250 | - | 282 | WP_010894533.1 | type II toxin-antitoxin system YafQ family toxin | - |
XFUD_RS09680 | 1973237..1973497 | - | 261 | WP_010894534.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | - |
XFUD_RS09685 | 1973827..1974633 | - | 807 | WP_010894535.1 | oxidoreductase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 11155.72 Da Isoelectric Point: 7.4670
>T49821 WP_010894527.1 NZ_CP009790:c1970461-1970165 [Xylella fastidiosa]
MPRVIFAPEAILNIQRLRNFLHPKNTDAARRAGEAIMRGARMLGAQPHIGRPVDDMPDEYREWLIDFGDSGYVARYHIDG
DTVTILAVRHHKEVGYTS
MPRVIFAPEAILNIQRLRNFLHPKNTDAARRAGEAIMRGARMLGAQPHIGRPVDDMPDEYREWLIDFGDSGYVARYHIDG
DTVTILAVRHHKEVGYTS
Download Length: 297 bp
>T49821 NZ_CP009790:c1970461-1970165 [Xylella fastidiosa]
ATGCCACGGGTGATCTTCGCTCCCGAAGCCATCCTGAACATTCAACGATTGCGGAATTTCCTGCATCCGAAGAACACCGA
TGCCGCAAGGCGGGCCGGTGAAGCCATCATGCGGGGTGCGCGGATGCTTGGAGCGCAGCCACATATCGGTCGTCCGGTTG
ATGATATGCCCGATGAGTACAGGGAATGGCTGATTGACTTCGGAGATAGCGGTTATGTGGCCCGCTACCACATTGATGGC
GATACCGTCACGATCTTGGCTGTTCGACACCATAAGGAAGTGGGATACACCAGCTGA
ATGCCACGGGTGATCTTCGCTCCCGAAGCCATCCTGAACATTCAACGATTGCGGAATTTCCTGCATCCGAAGAACACCGA
TGCCGCAAGGCGGGCCGGTGAAGCCATCATGCGGGGTGCGCGGATGCTTGGAGCGCAGCCACATATCGGTCGTCCGGTTG
ATGATATGCCCGATGAGTACAGGGAATGGCTGATTGACTTCGGAGATAGCGGTTATGTGGCCCGCTACCACATTGATGGC
GATACCGTCACGATCTTGGCTGTTCGACACCATAAGGAAGTGGGATACACCAGCTGA
Antitoxin
Download Length: 93 a.a. Molecular weight: 10772.08 Da Isoelectric Point: 5.6126
>AT49821 WP_010894528.1 NZ_CP009790:c1970727-1970449 [Xylella fastidiosa]
MGMATSIKLDDELKGRVQHLADVRRRTSHWIMREAIAQYVEREEKRETFRQDTLKAWEEFQATGLHVTTEEVEKWLSSWG
TENELSAPVCHG
MGMATSIKLDDELKGRVQHLADVRRRTSHWIMREAIAQYVEREEKRETFRQDTLKAWEEFQATGLHVTTEEVEKWLSSWG
TENELSAPVCHG
Download Length: 279 bp
>AT49821 NZ_CP009790:c1970727-1970449 [Xylella fastidiosa]
ATGGGCATGGCAACCTCCATCAAGCTTGATGATGAGCTGAAAGGACGTGTGCAGCATCTGGCCGATGTTCGCCGCCGCAC
TTCGCACTGGATCATGCGCGAGGCGATCGCGCAGTACGTTGAGCGTGAGGAAAAGCGTGAGACGTTTCGGCAGGACACGC
TGAAGGCATGGGAAGAGTTTCAGGCGACCGGCCTGCACGTGACGACCGAAGAAGTCGAGAAGTGGCTTTCGAGTTGGGGC
ACTGAAAATGAATTGTCAGCGCCCGTATGCCACGGGTGA
ATGGGCATGGCAACCTCCATCAAGCTTGATGATGAGCTGAAAGGACGTGTGCAGCATCTGGCCGATGTTCGCCGCCGCAC
TTCGCACTGGATCATGCGCGAGGCGATCGCGCAGTACGTTGAGCGTGAGGAAAAGCGTGAGACGTTTCGGCAGGACACGC
TGAAGGCATGGGAAGAGTTTCAGGCGACCGGCCTGCACGTGACGACCGAAGAAGTCGAGAAGTGGCTTTCGAGTTGGGGC
ACTGAAAATGAATTGTCAGCGCCCGTATGCCACGGGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1S0VAK4 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1S0V821 |