Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/COG3657-DUF971
Location 1624312..1624916 Replicon chromosome
Accession NZ_CP009790
Organism Xylella fastidiosa strain U24d

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag XFUD_RS07770 Protein ID WP_042463224.1
Coordinates 1624614..1624916 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag XFUD_RS07765 Protein ID WP_004089254.1
Coordinates 1624312..1624617 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XFUD_RS07715 1620176..1620352 + 177 WP_088371569.1 Blp family class II bacteriocin -
XFUD_RS07720 1620386..1620574 + 189 WP_010894166.1 hypothetical protein -
XFUD_RS07725 1620579..1620749 - 171 WP_010894167.1 antitoxin -
XFUD_RS07730 1620802..1621077 - 276 WP_042463219.1 type II toxin-antitoxin system RelE/ParE family toxin -
XFUD_RS07735 1621061..1621288 - 228 WP_031336679.1 CopG family transcriptional regulator -
XFUD_RS07740 1621399..1622169 + 771 WP_010894169.1 hypothetical protein -
XFUD_RS07745 1622169..1622486 + 318 WP_010894170.1 hypothetical protein -
XFUD_RS07750 1622483..1623313 + 831 WP_010894171.1 hypothetical protein -
XFUD_RS07755 1623310..1623951 + 642 WP_010894172.1 hypothetical protein -
XFUD_RS07760 1623948..1624301 + 354 WP_010894173.1 hypothetical protein -
XFUD_RS07765 1624312..1624617 - 306 WP_004089254.1 putative addiction module antidote protein Antitoxin
XFUD_RS07770 1624614..1624916 - 303 WP_042463224.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XFUD_RS07775 1625015..1626160 + 1146 WP_042463227.1 baseplate J/gp47 family protein -
XFUD_RS07780 1626157..1626717 + 561 WP_010894176.1 DUF2612 domain-containing protein -
XFUD_RS07785 1626721..1627884 + 1164 WP_010894177.1 phage tail protein -
XFUD_RS07790 1627917..1628396 - 480 WP_010894178.1 hypothetical protein -
XFUD_RS07795 1628430..1629545 - 1116 WP_010894179.1 HigA family addiction module antidote protein -
XFUD_RS07800 1629561..1629851 - 291 WP_010894180.1 type II toxin-antitoxin system RelE/ParE family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1585967..1628396 42429


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(49-95)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11048.87 Da        Isoelectric Point: 9.6861

>T49819 WP_042463224.1 NZ_CP009790:c1624916-1624614 [Xylella fastidiosa]
MVELIKTSTFDAWINSLRDRKAAARIQARLDRLALGNPGDVKPVGAGISEMRIDHGPGYRIYFMKHGAVLILLLCGGDKS
SQMRDIEQAKALAALWKDEP

Download         Length: 303 bp

>T49819 NZ_CP009790:c1624916-1624614 [Xylella fastidiosa]
ATGGTCGAACTCATCAAAACCAGCACTTTTGATGCTTGGATAAACAGCTTACGTGACCGCAAAGCAGCCGCCAGAATTCA
AGCGCGTCTTGATCGGCTCGCACTTGGCAATCCCGGCGACGTGAAGCCTGTGGGTGCTGGCATCTCAGAAATGAGGATCG
ACCATGGGCCCGGATATCGGATCTATTTTATGAAGCATGGTGCAGTACTGATTCTCTTGCTTTGCGGTGGCGATAAATCG
TCACAAATGCGAGATATCGAGCAGGCCAAGGCACTGGCTGCACTGTGGAAGGATGAGCCATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10983.37 Da        Isoelectric Point: 5.0941

>AT49819 WP_004089254.1 NZ_CP009790:c1624617-1624312 [Xylella fastidiosa]
MNNETFSRYDTADYLKTEEDIAAYMEAVMEEGGRDNPAFIARALGAVARARNLSQLARDVGMSRQGLDKALSNDGNPSFS
TILKVAKALGLRMSFTPSSMS

Download         Length: 306 bp

>AT49819 NZ_CP009790:c1624617-1624312 [Xylella fastidiosa]
ATGAATAATGAGACGTTTAGTCGATACGACACCGCTGACTATCTCAAAACCGAAGAAGATATTGCGGCTTATATGGAAGC
CGTCATGGAAGAAGGTGGTAGGGATAATCCTGCTTTTATTGCACGGGCACTTGGTGCTGTCGCTCGTGCTCGTAATTTAA
GTCAGCTTGCTCGTGACGTTGGCATGTCCAGGCAAGGACTAGACAAAGCACTCTCTAATGACGGCAACCCAAGCTTCTCA
ACCATCTTAAAAGTGGCTAAGGCGCTTGGTTTACGGATGTCATTCACTCCTTCCTCTATGAGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References