Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasB-vapB/RelE-VagC
Location 1620579..1621077 Replicon chromosome
Accession NZ_CP009790
Organism Xylella fastidiosa strain U24d

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag XFUD_RS07730 Protein ID WP_042463219.1
Coordinates 1620802..1621077 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag XFUD_RS07725 Protein ID WP_010894167.1
Coordinates 1620579..1620749 (-) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XFUD_RS07700 1616953..1617390 + 438 WP_010894081.1 DUF3277 family protein -
XFUD_RS07705 1617387..1617809 + 423 WP_010894082.1 hypothetical protein -
XFUD_RS07710 1617957..1619846 + 1890 WP_010894164.1 hypothetical protein -
XFUD_RS07715 1620176..1620352 + 177 WP_088371569.1 Blp family class II bacteriocin -
XFUD_RS07720 1620386..1620574 + 189 WP_010894166.1 hypothetical protein -
XFUD_RS07725 1620579..1620749 - 171 WP_010894167.1 antitoxin Antitoxin
XFUD_RS07730 1620802..1621077 - 276 WP_042463219.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XFUD_RS07735 1621061..1621288 - 228 WP_031336679.1 CopG family transcriptional regulator -
XFUD_RS07740 1621399..1622169 + 771 WP_010894169.1 hypothetical protein -
XFUD_RS07745 1622169..1622486 + 318 WP_010894170.1 hypothetical protein -
XFUD_RS07750 1622483..1623313 + 831 WP_010894171.1 hypothetical protein -
XFUD_RS07755 1623310..1623951 + 642 WP_010894172.1 hypothetical protein -
XFUD_RS07760 1623948..1624301 + 354 WP_010894173.1 hypothetical protein -
XFUD_RS07765 1624312..1624617 - 306 WP_004089254.1 putative addiction module antidote protein -
XFUD_RS07770 1624614..1624916 - 303 WP_042463224.1 type II toxin-antitoxin system RelE/ParE family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1585967..1628396 42429


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin

SpoVT-AbrB domain

(16-54)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10471.13 Da        Isoelectric Point: 10.0494

>T49817 WP_042463219.1 NZ_CP009790:c1621077-1620802 [Xylella fastidiosa]
MAWTIDYTDTAKQQLRKLDKHMARRIVDFMDERIAGLENPRSSGKALTGPLGGFWRYRVGDFRVVCAIQDSVLRVLVVGV
GHRGEMYRREC

Download         Length: 276 bp

>T49817 NZ_CP009790:c1621077-1620802 [Xylella fastidiosa]
TTGGCCTGGACGATTGATTACACCGACACGGCCAAGCAGCAGTTACGCAAACTCGACAAGCACATGGCGCGGCGCATTGT
CGATTTCATGGATGAGCGCATCGCCGGACTAGAAAACCCACGCAGCAGTGGTAAAGCATTAACCGGACCACTTGGCGGCT
TTTGGCGTTATCGTGTTGGTGATTTCCGGGTCGTCTGCGCCATTCAAGATAGCGTTTTGCGCGTCCTTGTGGTGGGTGTT
GGTCACCGGGGTGAGATGTACCGACGAGAATGCTAG

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6478.52 Da        Isoelectric Point: 8.9195

>AT49817 WP_010894167.1 NZ_CP009790:c1620749-1620579 [Xylella fastidiosa]
MPISSPLSRTKEAKLFRNNRSQVVRIPVEFELPGDRVLIHPEEDKLIIEPITRPTN

Download         Length: 171 bp

>AT49817 NZ_CP009790:c1620749-1620579 [Xylella fastidiosa]
ATGCCAATTTCATCTCCGTTATCACGTACCAAGGAAGCGAAGCTATTCCGAAATAATCGTAGCCAGGTGGTACGAATTCC
CGTTGAATTCGAGCTGCCGGGTGATCGTGTTCTGATCCACCCTGAGGAGGACAAGCTCATTATTGAGCCGATCACCCGGC
CAACCAACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References