Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | FicTA/Fic(toxin) |
| Location | 1595533..1596329 | Replicon | chromosome |
| Accession | NZ_CP009790 | ||
| Organism | Xylella fastidiosa strain U24d | ||
Toxin (Protein)
| Gene name | VbhT | Uniprot ID | Q9PCU8 |
| Locus tag | XFUD_RS07525 | Protein ID | WP_010894152.1 |
| Coordinates | 1595718..1596329 (+) | Length | 204 a.a. |
Antitoxin (Protein)
| Gene name | VbhA | Uniprot ID | Q9PCU9 |
| Locus tag | XFUD_RS07520 | Protein ID | WP_010894151.1 |
| Coordinates | 1595533..1595721 (+) | Length | 63 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| XFUD_RS07480 | 1591158..1592084 | - | 927 | WP_010894143.1 | phage recombination protein Bet | - |
| XFUD_RS07485 | 1592100..1592921 | - | 822 | WP_010894144.1 | YfdQ family protein | - |
| XFUD_RS07490 | 1592942..1593316 | - | 375 | WP_010894145.1 | hypothetical protein | - |
| XFUD_RS07495 | 1593337..1593528 | - | 192 | WP_010894146.1 | hypothetical protein | - |
| XFUD_RS07500 | 1593552..1593743 | - | 192 | WP_010894147.1 | hypothetical protein | - |
| XFUD_RS07505 | 1593740..1594141 | - | 402 | WP_010894148.1 | hypothetical protein | - |
| XFUD_RS07510 | 1594141..1594599 | - | 459 | WP_010894149.1 | hypothetical protein | - |
| XFUD_RS07515 | 1594596..1595141 | - | 546 | WP_080507209.1 | hypothetical protein | - |
| XFUD_RS07520 | 1595533..1595721 | + | 189 | WP_010894151.1 | antitoxin VbhA family protein | Antitoxin |
| XFUD_RS07525 | 1595718..1596329 | + | 612 | WP_010894152.1 | Fic/DOC family protein | Toxin |
| XFUD_RS07530 | 1596380..1597054 | - | 675 | WP_042463200.1 | helix-turn-helix transcriptional regulator | - |
| XFUD_RS07535 | 1597139..1597384 | + | 246 | WP_042463203.1 | hypothetical protein | - |
| XFUD_RS07540 | 1597381..1597686 | - | 306 | WP_042463205.1 | hypothetical protein | - |
| XFUD_RS07545 | 1597827..1598012 | + | 186 | Protein_1357 | hypothetical protein | - |
| XFUD_RS07550 | 1598066..1598254 | + | 189 | WP_042463208.1 | hypothetical protein | - |
| XFUD_RS07555 | 1598251..1598499 | + | 249 | WP_010894156.1 | hypothetical protein | - |
| XFUD_RS07560 | 1598496..1598879 | + | 384 | WP_042463212.1 | hypothetical protein | - |
| XFUD_RS07565 | 1599083..1600195 | + | 1113 | WP_042463693.1 | Bro-N domain-containing protein | - |
| XFUD_RS07570 | 1600192..1600500 | + | 309 | WP_023906549.1 | DUF1376 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1585967..1628396 | 42429 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 204 a.a. Molecular weight: 22892.65 Da Isoelectric Point: 4.9498
>T49815 WP_010894152.1 NZ_CP009790:1595718-1596329 [Xylella fastidiosa]
MKYAGDRGDPYLDSETGVLRNLLGISDQGWLDKIESTLSFLRTSELRERPVKGKFDLAHLQEIHNRLFQDVYDWAGQIRQ
VEISKGNTMFAQQIAIQSAAQQIFGQLAKERFLCGLDAEEFSKRAGDYLGEINVLHPFREGNGRTQREFIAQLAQRAGYR
IDWGVVSQADMIKASIDAYNGDSSGLASIIREGISDQLFKDNE
MKYAGDRGDPYLDSETGVLRNLLGISDQGWLDKIESTLSFLRTSELRERPVKGKFDLAHLQEIHNRLFQDVYDWAGQIRQ
VEISKGNTMFAQQIAIQSAAQQIFGQLAKERFLCGLDAEEFSKRAGDYLGEINVLHPFREGNGRTQREFIAQLAQRAGYR
IDWGVVSQADMIKASIDAYNGDSSGLASIIREGISDQLFKDNE
Download Length: 612 bp
>T49815 NZ_CP009790:1595718-1596329 [Xylella fastidiosa]
ATGAAATACGCAGGGGATCGTGGTGATCCTTACCTGGACAGCGAAACAGGTGTTCTTCGTAATCTCCTTGGAATCAGCGA
TCAGGGGTGGCTCGATAAAATAGAGTCCACCCTTTCTTTTTTGCGAACCAGCGAATTGCGTGAGCGACCCGTAAAAGGCA
AATTTGATCTAGCGCATTTACAGGAAATCCATAATCGCCTTTTCCAGGATGTGTACGACTGGGCGGGTCAAATCCGTCAA
GTTGAAATCTCGAAAGGCAACACGATGTTTGCCCAGCAGATTGCGATTCAGAGTGCGGCGCAGCAGATCTTTGGGCAGCT
TGCTAAAGAGCGATTTTTGTGTGGCCTTGATGCTGAGGAATTCAGCAAACGGGCAGGTGATTATCTTGGTGAAATTAATG
TGCTTCACCCATTCCGCGAGGGAAATGGCAGGACGCAACGGGAATTCATCGCGCAATTGGCTCAGCGTGCAGGTTACCGG
ATCGACTGGGGCGTGGTCAGCCAGGCGGATATGATTAAAGCGTCAATCGACGCTTACAACGGGGATTCAAGCGGATTGGC
TAGTATCATTCGCGAAGGAATATCTGATCAGCTTTTTAAAGATAATGAGTAA
ATGAAATACGCAGGGGATCGTGGTGATCCTTACCTGGACAGCGAAACAGGTGTTCTTCGTAATCTCCTTGGAATCAGCGA
TCAGGGGTGGCTCGATAAAATAGAGTCCACCCTTTCTTTTTTGCGAACCAGCGAATTGCGTGAGCGACCCGTAAAAGGCA
AATTTGATCTAGCGCATTTACAGGAAATCCATAATCGCCTTTTCCAGGATGTGTACGACTGGGCGGGTCAAATCCGTCAA
GTTGAAATCTCGAAAGGCAACACGATGTTTGCCCAGCAGATTGCGATTCAGAGTGCGGCGCAGCAGATCTTTGGGCAGCT
TGCTAAAGAGCGATTTTTGTGTGGCCTTGATGCTGAGGAATTCAGCAAACGGGCAGGTGATTATCTTGGTGAAATTAATG
TGCTTCACCCATTCCGCGAGGGAAATGGCAGGACGCAACGGGAATTCATCGCGCAATTGGCTCAGCGTGCAGGTTACCGG
ATCGACTGGGGCGTGGTCAGCCAGGCGGATATGATTAAAGCGTCAATCGACGCTTACAACGGGGATTCAAGCGGATTGGC
TAGTATCATTCGCGAAGGAATATCTGATCAGCTTTTTAAAGATAATGAGTAA
Antitoxin
Download Length: 63 a.a. Molecular weight: 6885.83 Da Isoelectric Point: 4.9859
>AT49815 WP_010894151.1 NZ_CP009790:1595533-1595721 [Xylella fastidiosa]
MLTDHEKAERRAVVQSALASQRIEGLEPDAQAVVDAECWARGEMTIATAVDQYKARVRLQMA
MLTDHEKAERRAVVQSALASQRIEGLEPDAQAVVDAECWARGEMTIATAVDQYKARVRLQMA
Download Length: 189 bp
>AT49815 NZ_CP009790:1595533-1595721 [Xylella fastidiosa]
ATGCTGACAGATCATGAGAAAGCTGAACGCCGTGCTGTGGTGCAAAGCGCACTCGCAAGCCAACGCATTGAGGGGTTAGA
GCCGGATGCGCAGGCCGTGGTTGATGCTGAATGCTGGGCGCGTGGTGAAATGACTATCGCTACCGCCGTGGACCAGTACA
AAGCGCGTGTTCGGCTCCAGATGGCATGA
ATGCTGACAGATCATGAGAAAGCTGAACGCCGTGCTGTGGTGCAAAGCGCACTCGCAAGCCAACGCATTGAGGGGTTAGA
GCCGGATGCGCAGGCCGTGGTTGATGCTGAATGCTGGGCGCGTGGTGAAATGACTATCGCTACCGCCGTGGACCAGTACA
AAGCGCGTGTTCGGCTCCAGATGGCATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|