Detailed information of TA system TA049735

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 3269566..3270100
• Replicon: chromosome
• Accession: NZ_CP009781
• Organism: Yersinia aldovae 670-83

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: AT01_RS14880
• Protein ID: WP_042547679.1
• Coordinates: 3269810..3270100 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A1JJ37
• Locus tag: AT01_RS14875
• Protein ID: WP_005175264.1
• Coordinates: 3269566..3269820 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
AT01_RS14850	3264744..3266255	-	1512	WP_042547675.1	leucyl aminopeptidase	-
AT01_RS14855	3266535..3267629	+	1095	WP_042547676.1	LPS export ABC transporter permease LptF	-
AT01_RS14860	3267629..3268699	+	1071	WP_042547677.1	LPS export ABC transporter permease LptG	-
AT01_RS14870	3269100..3269270	+	171	Protein_2911	DUF4102 domain-containing protein	-
AT01_RS14875	3269566..3269820	+	255	WP_005175264.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
AT01_RS14880	3269810..3270100	+	291	WP_042547679.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
AT01_RS22120	3270252..3270626	-	375	Protein_2914	Cro/Cl family transcriptional regulator	-
AT01_RS14890	3270939..3274166	-	3228	WP_042547680.1	type I restriction endonuclease subunit R	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-75)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 11518.44 Da
• Isoelectric Point: 9.9254

>T49735 WP_042547679.1 NZ_CP009781:3269810-3270100 [Yersinia aldovae 670-83]
MTFNIDFDERALKEWYKLDKAIREQFKKKLRKLQENPYIESARLHGDLAGCFKIKLRASGFRLIYQVIDEEIVIWIVAVG
KREDEKAYDIARKRIQ

Nucleotide

• Length: 291 bp

>T49735 NZ_CP009781:3269810-3270100 [Yersinia aldovae 670-83]
ATGACCTTTAATATCGACTTTGACGAACGGGCATTAAAAGAATGGTACAAACTAGATAAAGCTATCCGAGAGCAATTTAA
AAAGAAACTAAGAAAGTTACAGGAAAATCCCTATATTGAGTCAGCACGTTTGCACGGTGATCTGGCTGGCTGTTTCAAAA
TAAAATTACGCGCATCTGGTTTTCGGTTAATTTACCAAGTTATCGATGAGGAGATTGTGATTTGGATCGTTGCTGTTGGT
AAACGGGAAGATGAAAAAGCTTATGATATTGCCAGGAAGCGAATCCAATAG

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9680.07 Da
• Isoelectric Point: 4.8283

>AT49735 WP_005175264.1 NZ_CP009781:3269566-3269820 [Yersinia aldovae 670-83]
MSTIQIRVDDELKKSAYQAFEKLNLSPSDALRLFLRYVAENEKLPFSEVSVMVSNQDEDADILAVVRERLKNPAKRIRVN
IDDL

Nucleotide

• Length: 255 bp

>AT49735 NZ_CP009781:3269566-3269820 [Yersinia aldovae 670-83]
ATGAGTACTATCCAAATTCGTGTGGATGATGAACTGAAGAAAAGTGCATATCAGGCGTTTGAAAAACTGAATCTTTCGCC
TTCTGATGCACTACGCCTGTTCCTACGTTATGTTGCAGAGAACGAAAAGCTGCCTTTTTCAGAAGTATCCGTCATGGTCA
GTAATCAAGATGAGGATGCTGATATTTTGGCTGTTGTCCGTGAACGTTTGAAAAATCCTGCCAAGCGTATCAGGGTAAAT
ATTGATGACCTTTAA

Structures

Antitoxin

• AlphaFold DB: A1JJ37