Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1826261..1826936 Replicon chromosome
Accession NZ_CP009781
Organism Yersinia aldovae 670-83

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag AT01_RS08410 Protein ID WP_042546813.1
Coordinates 1826261..1826689 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag AT01_RS08415 Protein ID WP_042546814.1
Coordinates 1826670..1826936 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AT01_RS08390 1822023..1822541 + 519 WP_004703421.1 flavodoxin FldB -
AT01_RS08395 1822629..1824035 - 1407 WP_042546810.1 cell envelope integrity protein CreD -
AT01_RS08400 1824128..1825555 - 1428 WP_042546811.1 two-component system sensor histidine kinase CreC -
AT01_RS08405 1825566..1826264 - 699 WP_042546812.1 two-component system response regulator CreB -
AT01_RS08410 1826261..1826689 - 429 WP_042546813.1 protein YgfX Toxin
AT01_RS08415 1826670..1826936 - 267 WP_042546814.1 FAD assembly factor SdhE Antitoxin
AT01_RS08420 1827261..1828253 + 993 WP_042546815.1 tRNA-modifying protein YgfZ -
AT01_RS08425 1828312..1828995 - 684 WP_086016810.1 hemolysin III family protein -
AT01_RS08430 1829314..1830063 - 750 WP_042546816.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 16495.31 Da        Isoelectric Point: 8.9700

>T49731 WP_042546813.1 NZ_CP009781:c1826689-1826261 [Yersinia aldovae 670-83]
VAQWRCDLRVSWHTQLFSLLAHGVLVILTLVAPWPQGYIALWLVLLTLVVFECIRSQKKITSCQGEIRLKSGNLVLWKRH
EWKVTKQPWITHYGVLLNLQQVSSCSTRKRLWLAADSMSEDEWRQLCVLLRYSFGSDDGESL

Download         Length: 429 bp

>T49731 NZ_CP009781:c1826689-1826261 [Yersinia aldovae 670-83]
GTGGCCCAGTGGCGATGTGACCTGCGGGTATCCTGGCATACTCAACTCTTCTCTTTATTAGCACACGGTGTATTGGTCAT
ATTAACGTTGGTGGCACCCTGGCCGCAGGGGTACATCGCTTTATGGCTGGTGTTACTGACGCTGGTGGTGTTTGAGTGTA
TCCGCAGCCAGAAGAAAATCACGTCCTGTCAGGGCGAAATCAGGTTAAAATCCGGCAATTTAGTGCTATGGAAAAGGCAC
GAATGGAAAGTGACCAAACAGCCGTGGATCACCCATTATGGCGTGTTGTTAAATTTACAGCAGGTCAGTAGCTGTTCGAC
GCGTAAACGTTTATGGCTGGCTGCCGACAGCATGTCGGAAGATGAGTGGCGGCAGTTATGTGTGCTGCTACGGTATTCAT
TTGGCTCTGATGACGGAGAAAGTCTATGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10515.09 Da        Isoelectric Point: 5.1403

>AT49731 WP_042546814.1 NZ_CP009781:c1826936-1826670 [Yersinia aldovae 670-83]
MEIDNKARIHWACRRGMRELDISIMPFFEYEYDGLSEHEKCVFIRLLECDDPDLFNWLMNHGEPQDSDLRQMVKLIQTRN
KARGPVAM

Download         Length: 267 bp

>AT49731 NZ_CP009781:c1826936-1826670 [Yersinia aldovae 670-83]
ATGGAAATTGATAATAAAGCCCGTATCCATTGGGCGTGCCGCCGTGGGATGCGTGAATTAGACATCTCTATCATGCCATT
TTTTGAATATGAGTATGATGGCTTGAGTGAACATGAGAAATGTGTGTTTATTCGTTTGCTTGAGTGTGATGATCCAGACT
TATTCAACTGGCTGATGAATCACGGGGAGCCGCAGGACAGTGATCTGCGTCAGATGGTCAAACTAATTCAAACACGAAAT
AAAGCCCGTGGCCCAGTGGCGATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References