Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parE-PrpA/CC2985(antitoxin)
Location 1364173..1364719 Replicon chromosome
Accession NZ_CP009781
Organism Yersinia aldovae 670-83

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag AT01_RS06265 Protein ID WP_042546511.1
Coordinates 1364423..1364719 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name PrpA Uniprot ID -
Locus tag AT01_RS06260 Protein ID WP_042546510.1
Coordinates 1364173..1364436 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AT01_RS06240 1359722..1360417 - 696 WP_042546507.1 IS6 family transposase -
AT01_RS06245 1360607..1361971 - 1365 WP_052489942.1 RES domain-containing protein -
AT01_RS06250 1362419..1363084 - 666 WP_082039713.1 CPBP family intramembrane metalloprotease -
AT01_RS06255 1363295..1363930 - 636 WP_042546509.1 recombinase family protein -
AT01_RS06260 1364173..1364436 + 264 WP_042546510.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
AT01_RS06265 1364423..1364719 + 297 WP_042546511.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AT01_RS06270 1365041..1366240 + 1200 WP_042546512.1 AAA family ATPase -
AT01_RS06275 1366249..1367217 + 969 WP_042546513.1 ParB/RepB/Spo0J family partition protein -
AT01_RS06285 1367667..1368134 - 468 WP_082039555.1 DUF4113 domain-containing protein -
AT01_RS06295 1368173..1369284 + 1112 WP_144404905.1 IS3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1357388..1377774 20386


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Antitoxin ParD

(4-74)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11427.05 Da        Isoelectric Point: 5.1100

>T49729 WP_042546511.1 NZ_CP009781:1364423-1364719 [Yersinia aldovae 670-83]
MKEINLTPKAIDDLENIWLYGQVQFGVVKADEYVARFSEIFDILARHEIGTQRPELGENIYSLPIEKHVIFFVPSESSIT
VIRILNQSQDVNRHISWR

Download         Length: 297 bp

>T49729 NZ_CP009781:1364423-1364719 [Yersinia aldovae 670-83]
ATGAAAGAGATTAATCTGACACCGAAAGCAATTGATGATTTGGAAAATATTTGGCTTTATGGTCAGGTACAATTTGGTGT
AGTCAAGGCGGATGAATATGTCGCTCGCTTTTCTGAAATATTTGATATTTTGGCCAGACATGAAATTGGTACACAACGAC
CTGAGTTAGGTGAAAATATTTATTCACTCCCTATTGAGAAGCATGTAATTTTTTTCGTTCCTTCAGAGTCTTCTATCACT
GTAATTCGTATTCTTAATCAATCACAAGATGTAAATCGTCACATTTCTTGGCGATAG

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9992.19 Da        Isoelectric Point: 4.6926

>AT49729 WP_042546510.1 NZ_CP009781:1364173-1364436 [Yersinia aldovae 670-83]
MARTMTVDVGEELRDFIDSLVSAGDYRTQSEVLRDALRLLREKQAESHLQSLRDLLAEGVSSGTPETWSKDVFIQRIKER
VNLNERD

Download         Length: 264 bp

>AT49729 NZ_CP009781:1364173-1364436 [Yersinia aldovae 670-83]
ATGGCCAGGACAATGACAGTAGATGTTGGCGAGGAACTTCGCGACTTCATCGATTCGCTGGTTAGCGCAGGTGATTATAG
AACTCAAAGCGAAGTGCTCCGTGATGCTTTGCGTTTATTGCGTGAAAAGCAGGCTGAGTCCCATTTGCAATCATTACGGG
ACTTGTTGGCTGAAGGGGTGAGTAGCGGCACTCCAGAAACATGGAGTAAAGATGTATTCATACAGCGAATAAAGGAAAGG
GTTAATCTGAATGAAAGAGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References