Detailed information of TA system TA049666

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): hipBA/HipA-HipB
• Location: 4910777..4912362
• Replicon: chromosome
• Accession: NZ_CP009769
• Organism: Pectobacterium brasiliense strain BC1

Toxin (Protein)

• Gene name: hipA
• Uniprot ID: -
• Locus tag: NC16_RS22385
• Protein ID: WP_039502506.1
• Coordinates: 4911043..4912362 (+)
• Length: 440 a.a.

Antitoxin (Protein)

• Gene name: hipB
• Uniprot ID: -
• Locus tag: NC16_RS22380
• Protein ID: WP_039498288.1
• Coordinates: 4910777..4911043 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• HipA, N-terminal subdomain 1 (4-103)

Antitoxin

• Cro/C1-type helix-turn-helix domain (13-65)

Sequences

Toxin

Protein

• Length: 440 a.a.
• Molecular weight: 49346.60 Da
• Isoelectric Point: 6.6896

>T49666 WP_039502506.1 NZ_CP009769:4911043-4912362 [Pectobacterium brasiliense]
MAALDVYMNGYRVGILTKTGSGAHHFSYDANWLGLPGSRPISLSMPLRHQPYQGDEVYNFFDNLLPDNPDIRRRIVARYH
TDSTQPFDLLAKVGQDSVGALQLVPQGTPVHDIKKIEYKTLSEQQLENILTGYLSDAPLGMIDTEDDFRISIAGAQEKTA
LLYLDDRWCLPLNATPTTHIIKLPIGKIESHSYSIDMSDSVENEYLCLLIAKAFGLPVPHCFMINAGKIKALAVERFDRK
YASDVSWIMRLPQEDFCQVLNVPSALKYENHGGPGISAIMSFLLGSVYPERDRYRFMQAQVLFWLLAATDGHAKNFSLFI
ESEGRYRLTPFYDILSMYPAMGGRGIDRREAKMAMGLTGSRGKKYAIEQIFPRHFFQTAKVVGFARESMENILAEFAHTV
DTVMTTVGSQLPVDFPTHISEAILAGLQARSRRLMSGWE

Nucleotide

• Length: 1320 bp

>T49666 NZ_CP009769:4911043-4912362 [Pectobacterium brasiliense]
ATGGCTGCGCTCGATGTTTACATGAACGGCTATCGGGTGGGGATTCTGACCAAAACGGGCAGTGGGGCACATCATTTTTC
CTATGATGCGAACTGGCTCGGATTGCCGGGGAGTCGCCCCATTTCGCTTTCTATGCCGCTACGTCATCAGCCCTATCAGG
GCGATGAAGTTTATAACTTTTTCGACAATCTGTTGCCGGATAACCCGGATATCAGAAGACGGATTGTCGCCAGGTATCAT
ACGGATTCCACTCAGCCGTTTGATCTGCTGGCTAAAGTGGGGCAAGACAGTGTCGGTGCGTTGCAATTAGTGCCGCAGGG
TACACCTGTGCACGATATAAAAAAGATCGAATATAAAACCTTATCCGAGCAGCAGCTTGAAAACATACTGACTGGATATT
TGTCCGATGCCCCGCTGGGTATGATTGATACTGAAGACGATTTTCGTATCTCTATCGCAGGTGCACAGGAAAAGACGGCG
TTGCTGTATCTGGATGATCGCTGGTGCCTGCCTCTCAATGCCACACCAACTACCCACATCATCAAGCTACCGATTGGTAA
AATCGAGAGTCACTCTTACTCAATTGATATGTCTGACAGCGTTGAAAATGAGTATCTGTGTTTGCTCATTGCCAAGGCAT
TTGGGTTACCAGTGCCGCACTGTTTTATGATCAACGCTGGCAAGATAAAGGCGTTGGCGGTGGAGCGTTTTGATCGTAAA
TACGCCTCGGATGTCAGTTGGATTATGCGGCTACCACAAGAGGATTTTTGTCAGGTATTAAACGTTCCTTCCGCACTGAA
ATATGAAAATCATGGTGGACCGGGTATTTCCGCCATTATGTCGTTTCTATTGGGTTCGGTTTATCCAGAAAGGGATCGTT
ATCGCTTTATGCAGGCTCAGGTACTGTTTTGGCTATTGGCTGCAACAGATGGTCATGCGAAAAATTTTTCCCTGTTTATT
GAATCTGAGGGACGATATCGACTCACGCCTTTCTATGACATTCTCTCTATGTATCCGGCGATGGGCGGACGGGGAATTGA
CCGCAGAGAGGCCAAAATGGCGATGGGATTAACTGGCTCAAGAGGCAAGAAATATGCGATTGAGCAGATCTTTCCCCGAC
ATTTTTTCCAGACGGCGAAGGTCGTTGGGTTTGCCAGAGAATCGATGGAAAACATTCTGGCGGAGTTTGCCCACACTGTT
GATACCGTCATGACGACTGTTGGAAGTCAACTGCCTGTGGATTTTCCTACTCATATCAGTGAGGCAATTCTGGCCGGATT
GCAGGCCAGATCGAGACGGCTCATGAGCGGATGGGAGTAA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 9973.29 Da
• Isoelectric Point: 9.7281

>AT49666 WP_039498288.1 NZ_CP009769:4910777-4911043 [Pectobacterium brasiliense]
MKITNSKQLSSYLKDVRITQKLSQVKVASKVGIRQDTVSSFEQHPDSTKLETFFKILSALNLELTVTPRNVDTTNNEASV
ASSWKEEW

Nucleotide

• Length: 267 bp

>AT49666 NZ_CP009769:4910777-4911043 [Pectobacterium brasiliense]
ATGAAGATCACCAACAGCAAGCAGCTTAGCAGCTATCTGAAAGATGTTCGTATCACGCAGAAGCTTTCACAAGTGAAAGT
GGCCAGTAAAGTGGGTATTCGCCAGGATACGGTATCCAGTTTCGAGCAACATCCTGATTCCACTAAGCTGGAAACCTTCT
TTAAAATCCTGTCGGCATTGAATTTAGAACTTACCGTTACGCCCAGGAATGTGGACACCACCAATAACGAAGCCTCTGTT
GCATCATCCTGGAAGGAAGAATGGTAA