Detailed information of TA system TA049665

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 4775177..4775712
• Replicon: chromosome
• Accession: NZ_CP009769
• Organism: Pectobacterium brasiliense strain BC1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: C6DJA0
• Locus tag: NC16_RS21760
• Protein ID: WP_015842269.1
• Coordinates: 4775425..4775712 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: NC16_RS21755
• Protein ID: WP_039501748.1
• Coordinates: 4775177..4775428 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
NC16_RS21730	4770810..4771322	-	513	WP_162274787.1	phenolic acid decarboxylase	-
NC16_RS21735	4771422..4772294	+	873	WP_039501754.1	LysR family transcriptional regulator	-
NC16_RS21740	4772337..4772960	-	624	WP_039284934.1	LysE family translocator	-
NC16_RS21745	4773228..4773983	+	756	WP_039501752.1	thiol:disulfide interchange protein DsbG	-
NC16_RS21750	4774017..4774922	-	906	WP_039501750.1	siderophore-interacting protein	-
NC16_RS21755	4775177..4775428	+	252	WP_039501748.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
NC16_RS21760	4775425..4775712	+	288	WP_015842269.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
NC16_RS21765	4775816..4777168	-	1353	WP_010296544.1	glutathione-disulfide reductase	-
NC16_RS21770	4777297..4778139	-	843	WP_010281707.1	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	-
NC16_RS21775	4778358..4779086	+	729	WP_014913663.1	DUF1266 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11074.15 Da
• Isoelectric Point: 10.3527

>T49665 WP_015842269.1 NZ_CP009769:4775425-4775712 [Pectobacterium brasiliense]
MSYSVKFREDALKEWLKLDKTIQQQFAKKLKKCCENPHIPSAKLRGMKDCYKIKLRASGFRLVYEVIDDVLIIAVVAVGK
RERSGVYHLASERMR

Nucleotide

• Length: 288 bp

>T49665 NZ_CP009769:4775425-4775712 [Pectobacterium brasiliense]
ATGAGCTATAGCGTCAAATTCAGGGAAGATGCGCTGAAAGAATGGCTCAAGCTCGATAAAACCATCCAGCAGCAATTTGC
CAAAAAACTAAAAAAATGCTGCGAAAATCCCCATATTCCTTCGGCAAAGTTACGAGGGATGAAGGACTGCTACAAAATAA
AGCTCCGAGCATCAGGCTTTCGTTTGGTTTATGAGGTTATTGACGACGTATTGATTATCGCCGTAGTGGCGGTAGGTAAA
CGTGAGCGCAGCGGTGTTTATCATCTGGCGAGTGAGCGAATGAGATAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9161.52 Da
• Isoelectric Point: 4.0637

>AT49665 WP_039501748.1 NZ_CP009769:4775177-4775428 [Pectobacterium brasiliense]
MPNIILSDTTASVSELKKNPMTTVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL

Nucleotide

• Length: 252 bp

>AT49665 NZ_CP009769:4775177-4775428 [Pectobacterium brasiliense]
ATGCCGAATATTATATTGAGTGATACCACTGCAAGCGTCAGTGAACTGAAAAAGAACCCAATGACGACAGTCAATGCTGG
CGATGGCCTGCCTGTTGCTATCTTGAACCGCAACCAGCCTGCGTTTTATTGCATTCCTGCGGATCTCTACGAAAAAATGC
TGGATGCGCTGGACGATCAAGAACTGGTTAAGCTAATCGGTGAACGCAAAAACCAACCGCTGGTTGACGTGGATTTGGAT
AGTTTCCTATGA

Structures

Toxin

• AlphaFold DB: A0A3S0XQ75