Detailed information of TA system TA049661

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 3391267..3391901
• Replicon: chromosome
• Accession: NZ_CP009769
• Organism: Pectobacterium brasiliense strain BC1

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: NC16_RS15435
• Protein ID: WP_039503077.1
• Coordinates: 3391497..3391901 (+)
• Length: 135 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: A0A1V2R781
• Locus tag: NC16_RS15430
• Protein ID: WP_039360473.1
• Coordinates: 3391267..3391497 (+)
• Length: 77 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3372990..3399903	26913

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (4-124)

Antitoxin

• SpoVT-AbrB domain (7-53)

Sequences

Toxin

Protein

• Length: 135 a.a.
• Molecular weight: 15106.29 Da
• Isoelectric Point: 7.2741

>T49661 WP_039503077.1 NZ_CP009769:3391497-3391901 [Pectobacterium brasiliense]
MLKYLLDTNICIYTIKNKPQEVRDAFYRHYGQFAISAITLMELIYGAEKSINPEKNLAVIEGFSARLEVQNYGFDAAVHT
GQIRAELAKQGTSIGPYDAMLAGHARSEGLILVTNNVREFERVPGLRVENWVSR

Nucleotide

• Length: 405 bp

>T49661 NZ_CP009769:3391497-3391901 [Pectobacterium brasiliense]
ATGCTGAAATATCTGCTCGATACCAATATCTGTATTTACACCATCAAGAACAAACCGCAGGAAGTCAGGGACGCTTTCTA
CCGCCATTACGGGCAGTTTGCTATCAGTGCTATCACGCTGATGGAGCTGATCTATGGTGCGGAGAAATCGATAAATCCAG
AAAAGAATCTCGCCGTGATTGAAGGGTTTTCTGCCCGTCTGGAGGTTCAAAACTACGGTTTTGACGCCGCAGTGCATACC
GGCCAAATTCGTGCGGAACTGGCAAAACAAGGAACATCCATCGGCCCGTATGATGCCATGCTAGCGGGTCATGCTCGGTC
AGAAGGTTTGATACTGGTAACGAACAATGTGCGTGAATTTGAGCGTGTGCCTGGGCTACGTGTGGAAAACTGGGTCAGTC
GATAA

Antitoxin

Protein

• Length: 77 a.a.
• Molecular weight: 8707.79 Da
• Isoelectric Point: 4.4091

>AT49661 WP_039360473.1 NZ_CP009769:3391267-3391497 [Pectobacterium brasiliense]
MEKTTVFKSNRSQAVRLPKAVALPDDVKQVDIVAIGRTRIITPAGESWDSWFEEQGVTPDFMITREQPDDQIREDF

Nucleotide

• Length: 231 bp

>AT49661 NZ_CP009769:3391267-3391497 [Pectobacterium brasiliense]
ATGGAAAAAACCACAGTATTTAAAAGCAATCGCAGTCAAGCAGTACGACTCCCCAAAGCCGTTGCGCTGCCCGATGATGT
CAAGCAGGTTGATATCGTTGCGATTGGTCGCACACGTATCATTACCCCGGCAGGGGAAAGCTGGGACAGTTGGTTCGAAG
AACAAGGAGTAACACCTGACTTTATGATCACCAGAGAGCAACCCGATGATCAGATCAGGGAAGATTTCTGA

Structures

Antitoxin

• AlphaFold DB: A0A1V2R781