49656

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 703590..704250 Replicon chromosome
Accession NZ_CP009769
Organism Pectobacterium brasiliense strain BC1

Toxin (Protein)


Gene name cptA Uniprot ID A0A837DIN4
Locus tag NC16_RS03280 Protein ID WP_039275532.1
Coordinates 703837..704250 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A1D7Z1Z6
Locus tag NC16_RS03275 Protein ID WP_005971623.1
Coordinates 703590..703856 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NC16_RS03255 699417..700421 - 1005 WP_039510704.1 LacI family DNA-binding transcriptional regulator -
NC16_RS03260 700476..701084 - 609 WP_014914174.1 HD domain-containing protein -
NC16_RS03265 701515..702162 + 648 WP_010279833.1 hemolysin III family protein -
NC16_RS03270 702353..703354 - 1002 WP_075277840.1 tRNA-modifying protein YgfZ -
NC16_RS03275 703590..703856 + 267 WP_005971623.1 FAD assembly factor SdhE Antitoxin
NC16_RS03280 703837..704250 + 414 WP_039275532.1 protein YgfX Toxin
NC16_RS03285 704319..705254 + 936 WP_039502194.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
NC16_RS03290 705320..705643 - 324 WP_014914177.1 hypothetical protein -
NC16_RS03295 705672..706190 - 519 WP_014914178.1 flavodoxin FldB -
NC16_RS03300 706533..706919 - 387 WP_039282122.1 thioesterase family protein -
NC16_RS03305 707124..708452 - 1329 WP_039502195.1 MHS family MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16311.26 Da        Isoelectric Point: 10.7911

>T49656 WP_039275532.1 NZ_CP009769:703837-704250 [Pectobacterium brasiliense]
VAQWRCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQ
EWQIVKRPWLLKNGVLLSLQAVNGKDKQQLWLASDSMGDDEWRHLRQILLQQKHWAR

Download         Length: 414 bp

>T49656 NZ_CP009769:703837-704250 [Pectobacterium brasiliense]
GTGGCCCAGTGGCGATGTGACCTTCGCGTTTCCTGGCGCATGCAACTGTTATCATTGGTTGTGCATGGCCTATTAGTATT
GCTCATTCTGCTGGCACCGTGGCCGGACGGCTATGCGTGGCTATGGTTATGCCTGGTCACGATGGTGATGTTCGGTTTTA
TCCGTAGCCAACGGAATATTAAATCCCGACAGGGGGAAATCGTTCTGCTCAGCGAAACGACCCTGAACTGGCGGCAGCAG
GAATGGCAGATCGTTAAACGACCGTGGCTGCTGAAGAATGGCGTATTACTGTCATTGCAAGCGGTTAACGGTAAAGACAA
GCAGCAGCTGTGGCTGGCATCGGACAGCATGGGCGATGACGAATGGCGTCACTTGCGTCAAATTCTTTTGCAGCAGAAAC
ACTGGGCAAGATAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10507.94 Da        Isoelectric Point: 5.1392

>AT49656 WP_005971623.1 NZ_CP009769:703590-703856 [Pectobacterium brasiliense]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELKRMISLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT49656 NZ_CP009769:703590-703856 [Pectobacterium brasiliense]
ATGGAAATCGATAATAAATCACGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAATTGGATATCGCGATCATGCCGTT
TTTTGAGCATGACTATGACACACTTAATGACACTGATAAGCGCACGTTTGTACGCTTGTTACAAAGCGACGATCCCGATT
TATTCAACTGGCTGATGAACCACGGTGAACCGGAGGACGGAGAGCTGAAACGTATGATTTCCCTTATTCAGACGCGAAAT
AAAGATCGTGGCCCAGTGGCGATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A837DIN4

Antitoxin

Source ID Structure
AlphaFold DB A0A1D7Z1Z6

References