Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 95157..95679 Replicon plasmid pFORC7
Accession NZ_CP009767
Organism Salmonella enterica subsp. enterica serovar Enteritidis strain FORC_007

Toxin (Protein)


Gene name relE Uniprot ID D0QMR1
Locus tag FORC7_RS00560 Protein ID WP_000220561.1
Coordinates 95157..95438 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID G3CAG1
Locus tag FORC7_RS00565 Protein ID WP_000121743.1
Coordinates 95428..95679 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FORC7_RS00525 91139..91684 - 546 WP_000757692.1 hypothetical protein -
FORC7_RS25445 91679..91753 - 75 Protein_109 DNA distortion polypeptide 3 -
FORC7_RS23305 92010..92282 - 273 WP_000167280.1 hypothetical protein -
FORC7_RS23310 92515..92694 - 180 WP_000439079.1 hypothetical protein -
FORC7_RS00535 92737..93066 - 330 WP_000866654.1 hypothetical protein -
FORC7_RS00540 93160..93402 - 243 WP_000008708.1 hypothetical protein -
FORC7_RS00545 93392..93604 - 213 WP_001446884.1 hypothetical protein -
FORC7_RS00550 93670..94218 - 549 WP_001178641.1 hypothetical protein -
FORC7_RS00555 94292..94807 - 516 WP_001025387.1 J domain-containing protein -
FORC7_RS00560 95157..95438 - 282 WP_000220561.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FORC7_RS00565 95428..95679 - 252 WP_000121743.1 plasmid stabilization protein Antitoxin
FORC7_RS00570 96744..97613 + 870 WP_001212191.1 replication initiation protein -
FORC7_RS00575 97618..98469 + 852 WP_000435059.1 replication initiation protein -
FORC7_RS00580 98473..98919 + 447 WP_001074378.1 hypothetical protein -
FORC7_RS00585 98987..99409 + 423 WP_000202950.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..101428 101428


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 13852.62 Da        Isoelectric Point: 5.5500

>T49651 WP_000220561.1 NZ_CP009767:c95438-95157 [Salmonella enterica subsp. enterica serovar Enteritidis]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFF

Download         Length: 282 bp

>T49651 NZ_CP009767:c95438-95157 [Salmonella enterica subsp. enterica serovar Enteritidis]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 12380.85 Da        Isoelectric Point: 5.5500

>AT49651 WP_000121743.1 NZ_CP009767:c95679-95428 [Salmonella enterica subsp. enterica serovar Enteritidis]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFF

Download         Length: 252 bp

>AT49651 NZ_CP009767:c95679-95428 [Salmonella enterica subsp. enterica serovar Enteritidis]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3S5I302

Antitoxin

Source ID Structure
AlphaFold DB A0A3S5I301

References