49589

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4495731..4496116 Replicon chromosome
Accession NZ_CP009750
Organism Xanthomonas translucens pv. undulosa strain ICMP11055

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag NZ30_RS19355 Protein ID WP_003469322.1
Coordinates 4495731..4495865 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A1C3TTT1
Locus tag NZ30_RS19360 Protein ID WP_003469323.1
Coordinates 4495964..4496116 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NZ30_RS19340 4492180..4493103 - 924 WP_108085243.1 MBL fold metallo-hydrolase -
NZ30_RS19345 4493159..4494559 - 1401 WP_003469320.1 tryptophan--tRNA ligase -
NZ30_RS19350 4494670..4495521 + 852 WP_108085244.1 hypothetical protein -
NZ30_RS19355 4495731..4495865 - 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
NZ30_RS19360 4495964..4496116 - 153 WP_003469323.1 entericidin A/B family lipoprotein Antitoxin
NZ30_RS19365 4496261..4497183 - 923 Protein_3859 arginase -
NZ30_RS19375 4497571..4498389 - 819 WP_047325438.1 SPOR domain-containing protein -
NZ30_RS19380 4498399..4499139 - 741 WP_108085245.1 type III pantothenate kinase -
NZ30_RS19385 4499136..4500107 - 972 WP_108085246.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
NZ30_RS19390 4500269..4500541 + 273 WP_199222564.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-39)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T49589 WP_003469322.1 NZ_CP009750:c4495865-4495731 [Xanthomonas translucens pv. undulosa]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T49589 NZ_CP009750:c4495865-4495731 [Xanthomonas translucens pv. undulosa]
ATGAAGCGTACTTTCGCGTGGATGCTGCTGGCGATGTTCTCGGTGGGCCTGCTGTCGGGCTGCAACACGGTTGCCGGTGC
CGGCAAGGACGTGAAGAGCGCCGGCGAGAAGGTCGAAGACGCCGCCAAGAACTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5350.35 Da        Isoelectric Point: 8.1210

>AT49589 WP_003469323.1 NZ_CP009750:c4496116-4495964 [Xanthomonas translucens pv. undulosa]
MKRLFTLTMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVETKADDCKDGKC

Download         Length: 153 bp

>AT49589 NZ_CP009750:c4496116-4495964 [Xanthomonas translucens pv. undulosa]
ATGAAGCGACTGTTCACCTTGACGATGCTGACCCTGTTTTGTGCAGGCATGCTGACCGGCTGCAACACCATGGCCGGCGC
CGGTAAGGACATGCAGAAGGCCGGCGATAAGGTGGAAACCAAGGCCGACGACTGTAAAGACGGCAAGTGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5


Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TTT1

References