Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 1057185..1057690 Replicon chromosome
Accession NZ_CP009750
Organism Xanthomonas translucens pv. undulosa strain ICMP11055

Toxin (Protein)


Gene name relE Uniprot ID A0A2S0NY60
Locus tag NZ30_RS04710 Protein ID WP_003468814.1
Coordinates 1057185..1057442 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A1C3TRJ9
Locus tag NZ30_RS04715 Protein ID WP_003468816.1
Coordinates 1057439..1057690 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NZ30_RS04680 1052417..1053766 + 1350 WP_058363674.1 aminodeoxychorismate synthase component I -
NZ30_RS04685 1053836..1054903 + 1068 WP_170873989.1 endolytic transglycosylase MltG -
NZ30_RS04690 1054900..1055568 + 669 WP_003468811.1 dTMP kinase -
NZ30_RS04695 1055565..1056542 + 978 WP_003468812.1 DNA polymerase III subunit delta' -
NZ30_RS04700 1056539..1056892 + 354 WP_003468813.1 PilZ domain-containing protein -
NZ30_RS04710 1057185..1057442 - 258 WP_003468814.1 Txe/YoeB family addiction module toxin Toxin
NZ30_RS04715 1057439..1057690 - 252 WP_003468816.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NZ30_RS04720 1057846..1058610 + 765 WP_003468819.1 endonuclease -
NZ30_RS04725 1058607..1059329 - 723 WP_003468821.1 ArsR family transcriptional regulator -
NZ30_RS04730 1059453..1059902 + 450 WP_003468823.1 nuclear transport factor 2 family protein -
NZ30_RS04735 1060071..1060760 + 690 WP_196479346.1 hypothetical protein -
NZ30_RS04740 1060928..1061203 - 276 WP_003468826.1 hypothetical protein -
NZ30_RS04745 1061538..1061828 + 291 WP_003468827.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10173.68 Da        Isoelectric Point: 9.6587

>T49588 WP_003468814.1 NZ_CP009750:c1057442-1057185 [Xanthomonas translucens pv. undulosa]
VTLQFSDNAWEDYLYWQQTDKKMLKRINDLIKAIQRDPFQGVGKPEPLRHALAGYWSRRINDEHRIVYKVEAGVLLIAQV
RYHYV

Download         Length: 258 bp

>T49588 NZ_CP009750:c1057442-1057185 [Xanthomonas translucens pv. undulosa]
GTGACGCTTCAGTTCTCGGACAATGCCTGGGAGGACTACCTCTACTGGCAGCAGACCGACAAGAAGATGCTCAAGCGCAT
CAACGACCTGATCAAAGCCATTCAACGCGATCCCTTCCAGGGCGTCGGCAAGCCAGAACCGCTACGCCATGCCTTGGCCG
GCTATTGGTCGCGGCGCATCAACGACGAACATCGCATCGTGTACAAGGTCGAGGCGGGCGTCCTGCTGATCGCGCAGGTG
CGCTACCACTACGTGTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9281.56 Da        Isoelectric Point: 5.1186

>AT49588 WP_003468816.1 NZ_CP009750:c1057690-1057439 [Xanthomonas translucens pv. undulosa]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE

Download         Length: 252 bp

>AT49588 NZ_CP009750:c1057690-1057439 [Xanthomonas translucens pv. undulosa]
ATGGACACCATCACCTATAGCGCTGCACGCGCCGCCCTTGCGGACACCATGGAGCGCGTCGTCAACAACCACGAGCCGGT
GATCATCACCCGCAGCCGCGAGCAATCCGTGGTCATGCTGTCGCTTGAAGACTACAAGGCGATGGAGGAAACCGCCTACC
TGCTCCGCAGTCCGAAGAGCGCGCAGCGCCTGCTGGAATCCATCGCCCAGCTCGAGGCCGGTCGCGGCAAGGCACGGGAC
CTGGCCGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2S0NY60

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TRJ9

References