Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/Tad-HTH_37
Location 3133197..3133879 Replicon chromosome
Accession NZ_CP009744
Organism Burkholderia contaminans strain MS14

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag NL30_RS29760 Protein ID WP_047852432.1
Coordinates 3133197..3133559 (+) Length 121 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag NL30_RS29765 Protein ID WP_046544689.1
Coordinates 3133556..3133879 (+) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL30_RS29735 3129026..3129481 + 456 WP_046544694.1 VOC family protein -
NL30_RS29740 3129549..3131099 - 1551 WP_047852429.1 sodium:solute symporter family protein -
NL30_RS29745 3131096..3131338 - 243 WP_046544692.1 DUF3311 domain-containing protein -
NL30_RS29750 3131537..3132454 - 918 WP_047852430.1 spermidine synthase -
NL30_RS29755 3132599..3132853 + 255 WP_047852431.1 hypothetical protein -
NL30_RS29760 3133197..3133559 + 363 WP_047852432.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NL30_RS29765 3133556..3133879 + 324 WP_046544689.1 helix-turn-helix domain-containing protein Antitoxin
NL30_RS29770 3133934..3134410 - 477 WP_047852433.1 DNA-deoxyinosine glycosylase -
NL30_RS29775 3134410..3135006 - 597 WP_046546267.1 chorismate lyase -
NL30_RS29780 3135015..3136913 - 1899 WP_047852434.1 molecular chaperone HtpG -
NL30_RS29785 3137072..3138532 - 1461 WP_039370360.1 PLP-dependent aminotransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(16-109)

Antitoxin

Cro/C1-type helix-turn-helix domain

(30-85)


Sequences

Toxin        


Download         Length: 121 a.a.        Molecular weight: 13280.20 Da        Isoelectric Point: 9.7628

>T49578 WP_047852432.1 NZ_CP009744:3133197-3133559 [Burkholderia contaminans]
MDPYIKPLYWLGSARKDLKAMPQAVQDTFGYALYLAQTGRKHDQAKPLKGFGSAGVLEIVESEDNGTYRAVYTVKLGSSV
YVLHCFQKKSSIGIATPRPDSDLVHERLKAAEAHAQGVRR

Download         Length: 363 bp

>T49578 NZ_CP009744:3133197-3133559 [Burkholderia contaminans]
ATGGATCCATACATCAAACCGCTGTACTGGCTCGGCTCAGCGCGCAAGGATTTGAAAGCGATGCCGCAAGCCGTGCAGGA
CACGTTCGGCTATGCGCTGTATCTGGCGCAGACGGGACGCAAGCACGATCAGGCCAAGCCGTTGAAAGGATTCGGCTCGG
CCGGCGTGCTCGAGATCGTTGAATCGGAAGACAACGGCACGTATCGCGCGGTCTATACGGTGAAGCTCGGCAGCAGCGTG
TACGTGCTGCACTGTTTCCAGAAGAAGTCGTCGATCGGTATCGCAACACCGAGGCCGGACAGCGATCTCGTCCACGAACG
TCTGAAAGCGGCCGAAGCACACGCACAAGGAGTAAGGCGATGA

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11806.68 Da        Isoelectric Point: 7.3600

>AT49578 WP_046544689.1 NZ_CP009744:3133556-3133879 [Burkholderia contaminans]
MIEIEQGSGNVYADLGMHDAAEMRVKAQLAAKIAEIIKARQWTQQHAARLLGITQPKLSNMLRGQFRGVSETKMLECLAK
LGRDVHIVVGPDRQSEVEGHIEVVFAA

Download         Length: 324 bp

>AT49578 NZ_CP009744:3133556-3133879 [Burkholderia contaminans]
ATGATCGAAATCGAACAGGGCAGCGGGAACGTCTACGCCGATCTCGGCATGCACGATGCCGCCGAAATGCGGGTGAAAGC
CCAACTCGCCGCGAAGATCGCGGAAATCATCAAGGCGCGCCAATGGACACAGCAGCACGCGGCCCGGTTGCTCGGCATCA
CGCAGCCGAAGCTGTCGAACATGCTGCGCGGGCAGTTTCGCGGCGTCAGCGAAACGAAGATGCTCGAATGTCTGGCGAAG
CTCGGACGCGACGTGCACATCGTCGTCGGGCCCGATCGTCAATCGGAAGTCGAAGGGCACATCGAGGTCGTCTTCGCAGC
GTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References