Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /COG5642-COG5654
Location 220798..221781 Replicon chromosome
Accession NZ_CP009712
Organism Yersinia pseudotuberculosis IP 32953 strain IP32953

Toxin (Protein)


Gene name - Uniprot ID Q66A68
Locus tag BZ17_RS01560 Protein ID WP_011192520.1
Coordinates 220798..221256 (-) Length 153 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID Q66A69
Locus tag BZ17_RS01565 Protein ID WP_002210982.1
Coordinates 221335..221781 (-) Length 149 a.a.

Genomic Context

BZ17_RS01530BZ17_RS01535BZ17_RS01540BZ17_RS01545BZ17_RS01550BZ17_RS01555BZ17_RS01570BZ17_RS01580BZ17_RS01560BZ17_RS01565BZ17_RS01575BZ17_RS01585
Location: 216612..217277 (666 bp)
Type: Others
Protein ID: WP_011192521.1
Location: 217439..217666 (228 bp)
Type: Others
Protein ID: WP_002210976.1
Location: 217666..218025 (360 bp)
Type: Others
Protein ID: WP_002210977.1
Location: 218110..218352 (243 bp)
Type: Others
Protein ID: WP_002216375.1
Location: 218333..219730 (1398 bp)
Type: Others
Protein ID: WP_002210979.1
Location: 219727..220788 (1062 bp)
Type: Others
Protein ID: WP_002210980.1
Location: 222118..223695 (1578 bp)
Type: Others
Protein ID: WP_011192519.1
Location: 224525..225499 (975 bp)
Type: Others
Protein ID: WP_002210985.1
Location: 220798..221256 (459 bp)
Type: Toxin
Protein ID: WP_011192520.1
Location: 221335..221781 (447 bp)
Type: Antitoxin
Protein ID: WP_002210982.1
Location: 223859..224362 (504 bp)
Type: Others
Protein ID: WP_002210984.1
Location: 225541..226248 (708 bp)
Type: Others
Protein ID: WP_038823925.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BZ17_RS01530216612..217277+666WP_011192521.1phage shock protein PspA-
BZ17_RS01535217439..217666+228WP_002210976.1envelope stress response membrane protein PspB-
BZ17_RS01540217666..218025+360WP_002210977.1envelope stress response membrane protein PspC-
BZ17_RS01545218110..218352+243WP_002216375.1phage shock protein PspD-
BZ17_RS01550218333..219730+1398WP_002210979.1YcjX family protein-
BZ17_RS01555219727..220788+1062WP_002210980.1YcjF family protein-
BZ17_RS01560220798..221256-459WP_011192520.1RES family NAD+ phosphorylaseToxin
BZ17_RS01565221335..221781-447WP_002210982.1DUF2384 domain-containing proteinAntitoxin
BZ17_RS01570222118..223695+1578WP_011192519.1transcriptional regulator TyrR-
BZ17_RS01575223859..224362-504WP_002210984.1thiol peroxidase-
BZ17_RS01580224525..225499+975WP_002210985.1L-Ala-D/L-Glu epimerase-
BZ17_RS01585225541..226248-708WP_038823925.1murein tripeptide amidase MpaA-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(2-147)

Antitoxin

Antitoxin Xre

(15-147)


Sequences

Toxin        


Download         Length: 153 a.a.        Molecular weight: 17008.41 Da        Isoelectric Point: 4.8732

>T49503 WP_011192520.1 NZ_CP009712:c221256-220798 [Yersinia pseudotuberculosis IP 32953]
MTLYRIVMRRYLASAWTGYGAEIYGGRWNHKGHAAIYLASSISLAMLETLAHIQDSSTLSEFELFQIEISDSSIMLLQPQ
DWPTDWRSDPAPVATMDVGTEWLESESSLGLLVPSTLVPSENNLLVNPHHKDFPACLASVKPLSFVFDPRLK

Download         Length: 459 bp

>T49503 NZ_CP009712:c221256-220798 [Yersinia pseudotuberculosis IP 32953]
ATGACGCTATACCGCATTGTTATGCGCCGCTATCTTGCATCGGCATGGACTGGTTACGGCGCTGAAATCTATGGTGGTCG
TTGGAATCATAAAGGCCATGCTGCCATCTATTTAGCCAGCAGTATTTCATTGGCTATGCTCGAAACACTGGCTCATATTC
AGGACAGTTCAACACTCAGCGAATTTGAATTATTCCAAATTGAAATCAGTGACAGCAGTATTATGTTGCTACAGCCGCAG
GACTGGCCCACGGATTGGCGTAGCGATCCGGCACCGGTGGCAACGATGGATGTCGGCACCGAGTGGCTGGAATCAGAATC
CTCGCTAGGCTTACTGGTCCCGTCCACGTTGGTGCCGTCAGAAAACAACCTACTGGTCAATCCTCATCACAAAGATTTTC
CAGCGTGTTTGGCCAGCGTCAAACCGCTCTCTTTTGTCTTTGATCCACGGTTAAAATAG

Antitoxin


Download         Length: 149 a.a.        Molecular weight: 16401.94 Da        Isoelectric Point: 9.7155

>AT49503 WP_002210982.1 NZ_CP009712:c221781-221335 [Yersinia pseudotuberculosis IP 32953]
MRAYRPNPATKMGTLWREIGLPASRGTILVDSIKMGFSVDVIDSIHLWASMPKAEILRATGIPSRSLTRRRTHDGRFTPE
ESERIARFVRVMDAAVDLFGGDKGKAITWMSTPIKGLGYRSPDSLLETETGALEVCDLIGRLEHGVFT

Download         Length: 447 bp

>AT49503 NZ_CP009712:c221781-221335 [Yersinia pseudotuberculosis IP 32953]
ATGAGAGCGTACCGCCCAAACCCCGCGACTAAAATGGGAACGCTTTGGCGTGAAATTGGCTTACCCGCTAGCCGCGGCAC
GATATTGGTCGATAGTATCAAAATGGGGTTTTCTGTTGATGTTATCGACAGCATTCATTTATGGGCATCCATGCCTAAAG
CTGAAATATTACGTGCTACCGGTATCCCCAGCCGTAGCCTGACTCGCCGCCGCACACATGATGGCCGTTTTACGCCTGAA
GAAAGCGAGAGAATCGCACGTTTTGTCCGCGTAATGGATGCCGCTGTCGATTTGTTCGGCGGCGATAAAGGTAAAGCCAT
TACCTGGATGTCCACGCCCATCAAAGGATTGGGGTATCGCAGCCCAGACTCCTTACTGGAAACCGAAACTGGCGCACTGG
AAGTGTGTGATTTGATTGGTCGTTTGGAACACGGCGTCTTTACTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBQ66A68

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A0E8XFL1

References