Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1771167..1771438 Replicon chromosome
Accession NZ_CP009685
Organism Escherichia coli str. K-12 substr. MG1655 strain K-12

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1771297..1771400 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1771167..1771438 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EO53_RS08675 1767722..1768384 - 663 WP_000944256.1 exodeoxyribonuclease X -
EO53_RS08680 1768408..1769064 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
EO53_RS08685 1769166..1769396 - 231 WP_000916763.1 DNA polymerase III subunit theta -
EO53_RS08690 1769535..1769909 + 375 WP_000168747.1 CopC domain-containing protein YobA -
EO53_RS08695 1769913..1770785 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
EO53_RS08700 1770798..1771139 + 342 WP_000976476.1 YebY family protein -
- 1771167..1771438 - 272 - - Antitoxin
- 1771297..1771400 + 104 - - Toxin
EO53_RS08710 1771535..1772191 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
EO53_RS08715 1772192..1772383 - 192 WP_000457842.1 YebW family protein -
EO53_RS08720 1772488..1772724 - 237 WP_001295499.1 DUF1480 family protein -
EO53_RS08725 1772842..1774281 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T49436 NZ_CP009685:1771297-1771400 [Escherichia coli str. K-12 substr. MG1655]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT49436 NZ_CP009685:c1771438-1771167 [Escherichia coli str. K-12 substr. MG1655]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References