49397

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 3969188..3969828 Replicon chromosome
Accession NZ_CP009678
Organism Pectobacterium odoriferum strain BC S7

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag BCS7_RS18160 Protein ID WP_103165178.1
Coordinates 3969188..3969604 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID A0A094RPM0
Locus tag BCS7_RS18165 Protein ID WP_039490829.1
Coordinates 3969601..3969828 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BCS7_RS18140 3964727..3965710 - 984 WP_044208614.1 quinone oxidoreductase -
BCS7_RS18145 3965958..3967364 + 1407 WP_039490832.1 replicative DNA helicase -
BCS7_RS18150 3967406..3968488 + 1083 WP_039490831.1 alanine racemase -
BCS7_RS18155 3968481..3969119 + 639 WP_103165179.1 hypothetical protein -
BCS7_RS18160 3969188..3969604 - 417 WP_103165178.1 type II toxin-antitoxin system VapC family toxin Toxin
BCS7_RS18165 3969601..3969828 - 228 WP_039490829.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
BCS7_RS18170 3970801..3971280 + 480 WP_010295086.1 Lrp/AsnC family transcriptional regulator -
BCS7_RS18175 3971531..3972145 + 615 WP_039490827.1 YitT family protein -
BCS7_RS18180 3972210..3973403 + 1194 WP_103165177.1 aspartate/tyrosine/aromatic aminotransferase -
BCS7_RS18185 3973572..3974075 + 504 WP_044208625.1 M48 family metallopeptidase -
BCS7_RS18190 3974194..3974673 + 480 WP_010295094.1 Hcp family type VI secretion system effector -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-129)

Antitoxin

SpoVT-AbrB domain

(7-55)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15250.86 Da        Isoelectric Point: 8.5225

>T49397 WP_103165178.1 NZ_CP009678:c3969604-3969188 [Pectobacterium odoriferum]
VSRLFMLDTNICSFIMREHPAEMIEKLQQCTLRRDRIVVSAITYAEMRFGVVGKKASPRHMQLVDAFCRRLDAVLPWDCA
AVDATTKIKIALAAAGTPIGPNDTAIAGHAISAKAILVTNNLREFERVPGLTLEDWGK

Download         Length: 417 bp

>T49397 NZ_CP009678:c3969604-3969188 [Pectobacterium odoriferum]
GTGAGTCGTTTGTTCATGCTGGATACCAATATCTGTTCCTTCATTATGCGTGAACACCCTGCGGAGATGATTGAAAAGTT
GCAGCAGTGCACGCTGCGGCGTGATCGGATTGTGGTCTCTGCCATCACTTACGCTGAAATGCGTTTCGGGGTGGTTGGCA
AAAAAGCCTCGCCACGTCATATGCAACTCGTTGATGCTTTCTGTCGCCGACTTGATGCGGTGTTACCTTGGGATTGCGCC
GCAGTAGACGCTACGACGAAAATTAAAATCGCGCTAGCCGCAGCAGGCACGCCTATTGGCCCGAATGATACGGCCATCGC
AGGTCATGCCATCAGTGCTAAGGCCATATTGGTCACCAATAATCTGAGAGAATTTGAGCGAGTACCGGGGCTGACGTTGG
AAGATTGGGGTAAATAA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8861.99 Da        Isoelectric Point: 4.5098

>AT49397 WP_039490829.1 NZ_CP009678:c3969828-3969601 [Pectobacterium odoriferum]
MRIVSVFKNGNNRAIRLPRDMDFEGVNELEIVREGDTIILRPVKPNWHSFLQEDRADADFMTERQDVVEEGRFEL

Download         Length: 228 bp

>AT49397 NZ_CP009678:c3969828-3969601 [Pectobacterium odoriferum]
ATGCGTATTGTTTCGGTATTTAAAAACGGTAACAACCGTGCCATTCGTTTGCCACGTGATATGGACTTTGAAGGCGTCAA
CGAACTGGAGATTGTGCGTGAGGGAGATACCATCATACTGCGTCCGGTCAAACCCAATTGGCATTCGTTTTTGCAAGAAG
ATCGCGCTGACGCTGACTTTATGACAGAACGCCAGGATGTGGTCGAAGAGGGGAGATTCGAACTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A094RPM0

References