Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 1716735..1717288 Replicon chromosome
Accession NZ_CP009678
Organism Pectobacterium odoriferum strain BC S7

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag BCS7_RS07685 Protein ID WP_103164368.1
Coordinates 1716974..1717288 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag BCS7_RS07680 Protein ID WP_103162962.1
Coordinates 1716735..1716971 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BCS7_RS07665 1712929..1714136 + 1208 WP_111778462.1 IS3 family transposase -
BCS7_RS07670 1714213..1715178 - 966 WP_146619741.1 IS110 family transposase -
BCS7_RS07675 1715460..1716407 + 948 WP_103164367.1 DUF1738 domain-containing protein -
BCS7_RS07680 1716735..1716971 + 237 WP_103162962.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
BCS7_RS07685 1716974..1717288 + 315 WP_103164368.1 CcdB family protein Toxin
BCS7_RS07700 1717950..1718747 - 798 WP_103164369.1 DgsA anti-repressor MtfA -
BCS7_RS07710 1718988..1719329 - 342 Protein_1466 DUF1311 domain-containing protein -
BCS7_RS07715 1719461..1719916 + 456 WP_039493243.1 DUF2946 domain-containing protein -
BCS7_RS07720 1720031..1722043 + 2013 WP_103164370.1 TonB-dependent copper receptor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1688188..1719916 31728


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11563.53 Da        Isoelectric Point: 7.9859

>T49396 WP_103164368.1 NZ_CP009678:1716974-1717288 [Pectobacterium odoriferum]
MQFTVYGNTGKSVVYPLLLDVTSDIIGQLNRRIVIPLLPIEKYPAGRRPDRLVPVVRLTDGKEYAVMTHELASIPVQVLG
AVFCDASQYRTQVKAAIDFLIDGF

Download         Length: 315 bp

>T49396 NZ_CP009678:1716974-1717288 [Pectobacterium odoriferum]
ATGCAATTCACTGTATACGGTAATACCGGGAAAAGCGTCGTTTACCCGCTGTTGCTCGATGTCACGAGCGATATTATTGG
GCAATTGAATCGTCGTATAGTGATCCCATTGCTCCCTATTGAAAAGTATCCGGCAGGCCGCCGACCGGATCGCCTTGTTC
CCGTCGTCAGGCTGACGGACGGCAAAGAATACGCCGTAATGACCCACGAGCTGGCAAGTATCCCTGTTCAGGTTCTGGGG
GCGGTGTTTTGTGATGCGTCGCAGTACCGTACTCAGGTAAAGGCGGCAATAGACTTCCTCATCGACGGGTTCTGA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8977.03 Da        Isoelectric Point: 6.4610

>AT49396 WP_103162962.1 NZ_CP009678:1716735-1716971 [Pectobacterium odoriferum]
MTAKQRSTQSVTMTVERALLVRAREAGINLSATLTTALDAELRYHEAKKWQEENREALAALNRFHDEQGCFSDEYRTF

Download         Length: 237 bp

>AT49396 NZ_CP009678:1716735-1716971 [Pectobacterium odoriferum]
ATGACCGCGAAACAACGCAGCACGCAGAGTGTGACCATGACAGTAGAGCGTGCCTTACTGGTAAGAGCGCGTGAAGCGGG
CATTAATCTGAGTGCTACCCTGACAACCGCCCTGGATGCAGAGCTTCGCTATCATGAAGCGAAAAAATGGCAGGAAGAAA
ACAGGGAGGCGCTCGCAGCACTAAATCGTTTTCATGATGAGCAGGGTTGTTTCAGCGATGAATACAGGACGTTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References