Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 721931..722591 Replicon chromosome
Accession NZ_CP009678
Organism Pectobacterium odoriferum strain BC S7

Toxin (Protein)


Gene name cptA Uniprot ID A0A094S7H9
Locus tag BCS7_RS03315 Protein ID WP_039491174.1
Coordinates 722178..722591 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A1V2R9A9
Locus tag BCS7_RS03310 Protein ID WP_039355397.1
Coordinates 721931..722197 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BCS7_RS03285 717389..718138 + 750 WP_103164671.1 SDR family oxidoreductase -
BCS7_RS03290 718166..719050 - 885 Protein_627 LacI family DNA-binding transcriptional regulator -
BCS7_RS03295 719105..719713 - 609 WP_039491179.1 HD domain-containing protein -
BCS7_RS03300 719992..720639 + 648 WP_039491177.1 hemolysin III family protein -
BCS7_RS03305 720694..721695 - 1002 WP_039491175.1 tRNA-modifying protein YgfZ -
BCS7_RS03310 721931..722197 + 267 WP_039355397.1 FAD assembly factor SdhE Antitoxin
BCS7_RS03315 722178..722591 + 414 WP_039491174.1 protein YgfX Toxin
BCS7_RS03320 722660..723595 + 936 WP_039491172.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
BCS7_RS03325 723676..724194 - 519 WP_044204035.1 flavodoxin FldB -
BCS7_RS03330 724356..725681 - 1326 WP_039491171.1 MHS family MFS transporter -
BCS7_RS03335 726001..726899 + 899 Protein_636 site-specific tyrosine recombinase XerD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16359.31 Da        Isoelectric Point: 10.7911

>T49394 WP_039491174.1 NZ_CP009678:722178-722591 [Pectobacterium odoriferum]
VAQWRCDLRVSWRMQLLSLVVHGLLVLFILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQ
EWQIVKRPWLLKNGVLLSLQAVNAKDKQQLWLASDSMGDDEWRHLRQILLQQKHWAR

Download         Length: 414 bp

>T49394 NZ_CP009678:722178-722591 [Pectobacterium odoriferum]
GTGGCCCAGTGGCGATGTGACCTTCGCGTTTCCTGGCGCATGCAACTGCTGTCATTGGTGGTGCATGGCCTCTTAGTATT
ATTCATTCTGCTGGCACCGTGGCCGGACGGCTATGCGTGGCTATGGCTATGTCTGGTCACGATGGTGATGTTTGGTTTTA
TCCGTAGCCAAAGGAATATTAAATCCCGACAGGGGGAAATCGTTCTGCTCAGCGAAACGACCCTGAACTGGCGGCAGCAG
GAATGGCAAATCGTTAAACGACCGTGGCTGCTGAAGAATGGCGTGTTGCTGTCATTGCAGGCGGTTAACGCTAAAGACAA
GCAACAACTGTGGCTGGCATCGGACAGCATGGGCGATGACGAATGGCGTCACTTGCGTCAGATTCTTTTGCAGCAGAAAC
ACTGGGCAAGATAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10506.99 Da        Isoelectric Point: 6.2223

>AT49394 WP_039355397.1 NZ_CP009678:721931-722197 [Pectobacterium odoriferum]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPKDGELKRMISLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT49394 NZ_CP009678:721931-722197 [Pectobacterium odoriferum]
ATGGAAATCGATAATAAATCACGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAATTGGATATCGCGATCATGCCATT
TTTTGAGCATGACTATGACACACTTAATGATACTGATAAGCGTACGTTTGTACGTTTGTTACAAAGCGACGATCCCGATT
TATTCAACTGGCTGATGAACCACGGTGAACCGAAGGACGGAGAGCTGAAACGCATGATTTCCCTTATTCAGACGCGAAAT
AAAGACCGTGGCCCAGTGGCGATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A094S7H9

Antitoxin

Source ID Structure
AlphaFold DB A0A1V2R9A9

References