Detailed information of TA system TA049392

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 502929..503512
• Replicon: chromosome
• Accession: NZ_CP009678
• Organism: Pectobacterium odoriferum strain BC S7

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: BCS7_RS02310
• Protein ID: WP_103164608.1
• Coordinates: 503207..503512 (+)
• Length: 102 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A7V8PT23
• Locus tag: BCS7_RS02305
• Protein ID: WP_010296210.1
• Coordinates: 502929..503219 (+)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BCS7_RS02285	498063..499325	-	1263	WP_103164606.1	L-rhamnose isomerase	-
BCS7_RS02290	499322..500812	-	1491	WP_103164607.1	rhamnulokinase	-
BCS7_RS02295	501149..501988	+	840	WP_039493893.1	HTH-type transcriptional activator RhaS	-
BCS7_RS02300	502013..502867	+	855	WP_039507370.1	helix-turn-helix domain-containing protein	-
BCS7_RS02305	502929..503219	+	291	WP_010296210.1	ribbon-helix-helix protein, CopG family	Antitoxin
BCS7_RS02310	503207..503512	+	306	WP_103164608.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BCS7_RS02315	503631..505328	-	1698	WP_103164609.1	ABC transporter ATP-binding protein	-
BCS7_RS02320	505325..506191	-	867	WP_039493886.1	ABC transporter permease	-
BCS7_RS02325	506184..507143	-	960	WP_039470517.1	ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-96)

Antitoxin

• Ribbon-helix-helix protein, CopG (9-46)

Sequences

Toxin

Protein

• Length: 102 a.a.
• Molecular weight: 11620.54 Da
• Isoelectric Point: 9.8325

>T49392 WP_103164608.1 NZ_CP009678:503207-503512 [Pectobacterium odoriferum]
MPQVIVSERARRDLQRLQDFLKNKNVLAAKKAAEVLIRGIRQLEALPNIGRPVEHLPLEYQELVIEFGSSGYVMLYRHDE
LTGRVVILTVKHQKEAGYQNL

Nucleotide

• Length: 306 bp

>T49392 NZ_CP009678:503207-503512 [Pectobacterium odoriferum]
ATGCCACAAGTGATCGTTTCAGAACGCGCGAGGCGTGATTTGCAGCGTCTACAGGATTTTCTAAAAAACAAAAATGTGCT
GGCCGCGAAAAAGGCCGCTGAAGTTTTGATTCGGGGCATTCGTCAGTTAGAAGCGCTGCCGAATATCGGACGACCCGTGG
AACATCTTCCCCTTGAATATCAGGAACTGGTGATCGAGTTCGGCAGCAGTGGGTATGTGATGCTTTACCGTCACGATGAA
CTGACCGGCAGAGTAGTGATACTGACCGTTAAACATCAAAAAGAAGCCGGTTATCAAAACCTGTAA

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 11064.13 Da
• Isoelectric Point: 4.7692

>AT49392 WP_010296210.1 NZ_CP009678:502929-503219 [Pectobacterium odoriferum]
MADTTRQTTTLRIDQDIKERLKTLADDRNSSAHALMLEAIAEYVEREEKRSQYRKEALAAWEDYQDTGKHITADETVTWL
ESWGSGHEQDAPACHK

Nucleotide

• Length: 291 bp

>AT49392 NZ_CP009678:502929-503219 [Pectobacterium odoriferum]
ATGGCTGATACCACACGTCAAACCACGACGCTGCGCATCGATCAGGACATTAAAGAACGACTGAAAACGCTGGCCGATGA
CCGCAACAGCTCTGCCCATGCGCTAATGTTGGAAGCGATTGCCGAATACGTTGAGCGGGAAGAAAAACGCAGTCAGTACC
GTAAAGAGGCGTTGGCCGCGTGGGAAGACTATCAGGACACTGGCAAACATATCACCGCAGATGAGACCGTCACTTGGTTA
GAATCCTGGGGTTCTGGACATGAACAGGATGCGCCTGCATGCCACAAGTGA

Structures

Antitoxin

• AlphaFold DB: A0A7V8PT23