Detailed information of TA system TA049390

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 459023..459548
• Replicon: chromosome
• Accession: NZ_CP009678
• Organism: Pectobacterium odoriferum strain BC S7

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: BCS7_RS02125
• Protein ID: WP_039516597.1
• Coordinates: 459264..459548 (+)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: C6D956
• Locus tag: BCS7_RS02120
• Protein ID: WP_005973616.1
• Coordinates: 459023..459274 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BCS7_RS22505	454425..454610	-	186	WP_146043341.1	hypothetical protein	-
BCS7_RS02090	454597..454857	+	261	WP_103160153.1	AlpA family transcriptional regulator	-
BCS7_RS02095	454854..455077	+	224	Protein_398	hypothetical protein	-
BCS7_RS22510	455086..455475	+	390	Protein_399	hypothetical protein	-
BCS7_RS22515	455439..455636	+	198	WP_146043347.1	host cell division inhibitor Icd-like protein	-
BCS7_RS22520	455629..455823	+	195	WP_146043348.1	hypothetical protein	-
BCS7_RS02105	455820..456086	+	267	WP_103160155.1	hypothetical protein	-
BCS7_RS02110	456083..456424	+	342	WP_039513215.1	DUF5375 family protein	-
BCS7_RS02115	456435..458762	+	2328	WP_103164602.1	toprim domain-containing protein	-
BCS7_RS02120	459023..459274	+	252	WP_005973616.1	prevent-host-death protein	Antitoxin
BCS7_RS02125	459264..459548	+	285	WP_039516597.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BCS7_RS02130	460249..460677	+	429	WP_044206160.1	GNAT family N-acetyltransferase	-
BCS7_RS02135	460768..461889	+	1122	WP_103161875.1	cupin domain-containing protein	-
BCS7_RS02140	462189..463325	+	1137	WP_029367920.1	alpha/beta hydrolase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 11003.97 Da
• Isoelectric Point: 10.1716

>T49390 WP_039516597.1 NZ_CP009678:459264-459548 [Pectobacterium odoriferum]
MSYKLEFEEHALKEFKKLGAPVREQFTKKLKEVLQHPHVPANRLHGMADCYKIKLRSAGYRLVYQVLEHEIVVLVLAVGK
RERSEVYKAAKDRL

Nucleotide

• Length: 285 bp

>T49390 NZ_CP009678:459264-459548 [Pectobacterium odoriferum]
ATGAGTTATAAGCTGGAGTTTGAAGAGCACGCGCTGAAAGAATTTAAGAAGCTGGGTGCGCCCGTGCGGGAGCAGTTCAC
CAAAAAGTTGAAAGAGGTTTTACAACATCCCCACGTTCCCGCCAACCGACTTCATGGAATGGCTGACTGCTACAAAATCA
AACTTCGTTCCGCTGGCTATCGGCTAGTGTATCAAGTGCTTGAACATGAGATCGTAGTACTGGTTTTAGCTGTGGGCAAA
CGGGAACGCTCAGAGGTTTATAAAGCAGCCAAAGACCGACTATAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9079.35 Da
• Isoelectric Point: 5.0807

>AT49390 WP_005973616.1 NZ_CP009678:459023-459274 [Pectobacterium odoriferum]
MSVQPILANAAVSISDFKKSPNAALKEANGEPVAVLTNGRISGYYVSPETWEALADYQEDIELAKIARSRMKGKRVKVDL
DEL

Nucleotide

• Length: 252 bp

>AT49390 NZ_CP009678:459023-459274 [Pectobacterium odoriferum]
ATGTCCGTACAACCTATCCTTGCAAATGCAGCCGTGAGTATCAGCGACTTTAAAAAGTCCCCTAATGCCGCGCTTAAAGA
AGCTAACGGCGAGCCTGTAGCCGTGCTAACCAATGGCCGTATCTCTGGCTATTATGTTTCTCCTGAAACATGGGAAGCGC
TGGCCGATTATCAGGAAGATATCGAACTTGCCAAAATCGCCCGTTCCCGGATGAAGGGGAAACGTGTGAAGGTCGATCTG
GATGAGTTATAA

Structures

Antitoxin

• AlphaFold DB: A0A0G4JQP6