Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-DnaT
Location 352433..352964 Replicon chromosome
Accession NZ_CP009678
Organism Pectobacterium odoriferum strain BC S7

Toxin (Protein)


Gene name stbE Uniprot ID A0A7V8PTM5
Locus tag BCS7_RS01620 Protein ID WP_039470363.1
Coordinates 352677..352964 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID A0A3R8PFZ6
Locus tag BCS7_RS01615 Protein ID WP_039470361.1
Coordinates 352433..352687 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BCS7_RS01590 347912..348502 - 591 WP_039493037.1 DnaA initiator-associating protein DiaA -
BCS7_RS01595 348544..348939 - 396 WP_072009247.1 YraN family protein -
BCS7_RS01600 348897..350915 - 2019 WP_103164580.1 penicillin-binding protein activator -
BCS7_RS01605 350977..351864 + 888 WP_039493033.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
BCS7_RS01615 352433..352687 + 255 WP_039470361.1 plasmid stabilization protein Antitoxin
BCS7_RS01620 352677..352964 + 288 WP_039470363.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BCS7_RS01625 353141..353926 + 786 WP_039493030.1 4,5-DOPA dioxygenase extradiol -
BCS7_RS01630 354113..355273 - 1161 WP_039493028.1 glutathionylspermidine synthase family protein -
BCS7_RS01635 355285..355959 - 675 WP_010297420.1 DUF1190 family protein -
BCS7_RS01640 356224..357618 - 1395 WP_039493026.1 outer membrane channel protein TolC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10974.88 Da        Isoelectric Point: 10.6713

>T49389 WP_039470363.1 NZ_CP009678:352677-352964 [Pectobacterium odoriferum]
MTYKLKFVPSALKEWKKLGHPVREQFKKKLVERLENPHVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGVGK
REGSQIYSDTKGRSA

Download         Length: 288 bp

>T49389 NZ_CP009678:352677-352964 [Pectobacterium odoriferum]
ATGACCTATAAGTTAAAATTTGTGCCTTCTGCATTGAAGGAATGGAAAAAATTAGGGCACCCTGTCCGAGAGCAGTTCAA
GAAAAAGCTGGTTGAGCGTTTGGAAAATCCTCATGTTCCTTCAGCCCAACTTCATGGCCGTAAAGACCAGTATAAAATTA
AACTGAAGTCCGCTGGCTACAGGCTGGTGTATTTGGTCCAGGATGAGACCATTACTGTGATGGTTATGGGCGTTGGAAAG
CGCGAAGGTAGCCAGATTTATTCTGATACTAAAGGTCGTTCTGCTTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9192.34 Da        Isoelectric Point: 3.7947

>AT49389 WP_039470361.1 NZ_CP009678:352433-352687 [Pectobacterium odoriferum]
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAVFAYLMELAEDAELGRTVDDRMSELADAEEIS
PDDL

Download         Length: 255 bp

>AT49389 NZ_CP009678:352433-352687 [Pectobacterium odoriferum]
ATGGCTTTTAATATCCTAACTAACACCGCTGCCAGCATCACTGAGTTGAAACGTGACCCAATGGGTACAGTACGGGCTGC
TGAAGGTGAAACTATCGCTATACTGAACCGGAATGAGCCGGCGTTCTACTGTGTGCCTCCTGCCGTATTCGCTTATTTAA
TGGAACTGGCTGAAGATGCCGAACTGGGGCGTACCGTTGATGACCGGATGTCAGAACTAGCTGACGCGGAAGAGATTTCG
CCCGATGACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7V8PTM5

Antitoxin

Source ID Structure
AlphaFold DB A0A3R8PFZ6

References