Detailed information of TA system TA049387

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 34730..35265
• Replicon: chromosome
• Accession: NZ_CP009678
• Organism: Pectobacterium odoriferum strain BC S7

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: BCS7_RS00135
• Protein ID: WP_103162646.1
• Coordinates: 34730..35017 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: Q6DB37
• Locus tag: BCS7_RS00140
• Protein ID: WP_010281712.1
• Coordinates: 35014..35265 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BCS7_RS00120	31358..32086	-	729	WP_103160430.1	DUF1266 domain-containing protein	-
BCS7_RS00125	32305..33147	+	843	WP_039490258.1	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	-
BCS7_RS00130	33276..34628	+	1353	WP_039490257.1	glutathione-disulfide reductase	-
BCS7_RS00135	34730..35017	-	288	WP_103162646.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BCS7_RS00140	35014..35265	-	252	WP_010281712.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
BCS7_RS00145	35523..36428	+	906	WP_039490602.1	siderophore-interacting protein	-
BCS7_RS00150	36463..37218	-	756	WP_103165099.1	thiol:disulfide interchange protein DsbG	-
BCS7_RS00155	37497..38120	+	624	WP_039474438.1	LysE family translocator	-
BCS7_RS00160	38365..38802	-	438	WP_010296551.1	RICIN domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11083.21 Da
• Isoelectric Point: 10.4703

>T49387 WP_103162646.1 NZ_CP009678:c35017-34730 [Pectobacterium odoriferum]
MSYRVKFREDALKEWLKLDKAIQQQFAKKLKKCCENPHIPAAKLRGMKDCYKIKLRASGFRLVYEVIDDVLVIAVVAVGK
RERSGVYHLASERMR

Nucleotide

• Length: 288 bp

>T49387 NZ_CP009678:c35017-34730 [Pectobacterium odoriferum]
ATGAGTTATCGCGTCAAATTCAGGGAAGATGCGCTAAAAGAATGGCTCAAACTCGATAAAGCTATCCAACAACAATTTGC
CAAAAAACTAAAAAAATGCTGCGAAAATCCCCATATTCCTGCGGCAAAGTTACGGGGAATGAAGGATTGCTACAAAATAA
AGCTCCGAGCATCAGGCTTTCGTTTGGTTTATGAGGTTATTGACGACGTATTGGTTATCGCCGTGGTAGCGGTAGGCAAA
CGTGAGCGCAGCGGTGTTTATCATCTGGCGAGTGAGCGGATGAGGTAG

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9117.47 Da
• Isoelectric Point: 4.0637

>AT49387 WP_010281712.1 NZ_CP009678:c35265-35014 [Pectobacterium odoriferum]
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL

Nucleotide

• Length: 252 bp

>AT49387 NZ_CP009678:c35265-35014 [Pectobacterium odoriferum]
ATGCCGAATATTATATTAAGCGATACCAGTGCCAGCGTCAGTGAACTGAAAAAGAACCCGATGGCGACGGTCAACGCTGG
TGATGGCCTGCCTGTTGCTATCTTGAACCGCAACCAGCCTGCGTTTTATTGCATTCCTGCGGATCTCTACGAAAAAATGC
TGGATGCGCTGGACGATCAGGAGCTGGTTAAGCTGATCGGTGAACGTAAAAACCAGCCGCTGGTTGACGTGGATTTGGAT
AGTTTCCTATGA

Structures

Antitoxin

• AlphaFold DB: A0A0M2EZP0