Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 1739351..1739992 Replicon chromosome
Accession NZ_CP009630
Organism Burkholderia vietnamiensis LMG 10929

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag AK36_RS07710 Protein ID WP_045578204.1
Coordinates 1739351..1739689 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AK36_RS07715 Protein ID WP_011881499.1
Coordinates 1739693..1739992 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AK36_RS07700 1735892..1737325 - 1434 WP_045578203.1 aldehyde dehydrogenase family protein -
AK36_RS07705 1737354..1738994 - 1641 WP_011881501.1 acetolactate synthase large subunit -
AK36_RS07710 1739351..1739689 + 339 WP_045578204.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AK36_RS07715 1739693..1739992 + 300 WP_011881499.1 putative addiction module antidote protein Antitoxin
AK36_RS07720 1740073..1741359 - 1287 WP_045578205.1 DUF445 domain-containing protein -
AK36_RS07725 1741548..1742768 - 1221 WP_045578206.1 FAD-dependent oxidoreductase -
AK36_RS07730 1742758..1743084 - 327 WP_045578207.1 non-heme iron oxygenase ferredoxin subunit -
AK36_RS07735 1743111..1743596 - 486 WP_034194948.1 aromatic-ring-hydroxylating dioxygenase subunit beta -
AK36_RS07740 1743614..1744885 - 1272 WP_014724582.1 Rieske 2Fe-2S domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(26-98)

Antitoxin

Uncharacterized protein HI1420

(6-93)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12652.46 Da        Isoelectric Point: 9.4958

>T49341 WP_045578204.1 NZ_CP009630:1739351-1739689 [Burkholderia vietnamiensis LMG 10929]
MVDISSNVPYSAPTYSIRTTEVFDTWFAGLQDRVARRRIQARIDRLPMGNPGDWKSAGSPVVEMRIDHGPGYRVYYVRRA
TIWVILLCGGDKSTQQADIRAAHAMLGRLDLE

Download         Length: 339 bp

>T49341 NZ_CP009630:1739351-1739689 [Burkholderia vietnamiensis LMG 10929]
ATGGTTGACATATCGAGTAACGTGCCTTACAGTGCTCCGACGTACAGCATCAGAACGACCGAAGTCTTCGACACATGGTT
CGCCGGTCTGCAGGATCGCGTCGCACGGCGGCGTATCCAGGCCCGCATCGACCGCCTGCCGATGGGCAATCCGGGCGACT
GGAAGTCGGCCGGCTCCCCGGTCGTCGAGATGCGTATCGACCACGGCCCCGGCTATCGCGTCTACTACGTCAGGCGCGCG
ACGATCTGGGTGATCCTGCTCTGCGGCGGCGACAAGTCGACGCAACAGGCAGACATTCGCGCCGCGCACGCAATGCTCGG
GCGGCTCGACCTGGAGTAA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10548.87 Da        Isoelectric Point: 6.0633

>AT49341 WP_011881499.1 NZ_CP009630:1739693-1739992 [Burkholderia vietnamiensis LMG 10929]
MDKISTRPWDSAAHLETDDDIADYFDACLQEGGDDPAFIAHALGVIARARGMSQVARDAGLSREGLYKALSHDGNPSFGT
ILKVIKALGLQLHGAKARA

Download         Length: 300 bp

>AT49341 NZ_CP009630:1739693-1739992 [Burkholderia vietnamiensis LMG 10929]
ATGGACAAGATCAGCACCCGGCCGTGGGATTCGGCCGCCCACCTCGAAACCGACGACGACATCGCCGACTATTTCGACGC
GTGCCTGCAGGAAGGCGGCGACGACCCGGCCTTCATCGCGCATGCGCTCGGCGTGATCGCGCGCGCGCGCGGCATGTCGC
AGGTCGCCCGCGACGCCGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCACGACGGCAATCCGAGCTTCGGCACC
ATCCTCAAAGTGATCAAGGCGCTCGGCCTGCAACTGCACGGCGCGAAAGCGCGCGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References