Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /DUF1778(antitoxin) |
Location | 106734..107563 | Replicon | plasmid p319 |
Accession | NZ_CP009620 | ||
Organism | Vibrio coralliilyticus strain RE98 |
Toxin (Protein)
Gene name | - | Uniprot ID | A0A7Y4BPZ8 |
Locus tag | IX92_RS27680 | Protein ID | WP_043011727.1 |
Coordinates | 106734..107297 (-) | Length | 188 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | A0A7Y3YYU7 |
Locus tag | IX92_RS27685 | Protein ID | WP_040122444.1 |
Coordinates | 107294..107563 (-) | Length | 90 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
IX92_RS27670 | 101777..102745 | - | 969 | WP_043011721.1 | hypothetical protein | - |
IX92_RS27675 | 103214..105307 | - | 2094 | WP_043011724.1 | TonB-dependent siderophore receptor | - |
IX92_RS27680 | 106734..107297 | - | 564 | WP_043011727.1 | GNAT family N-acetyltransferase | Toxin |
IX92_RS27685 | 107294..107563 | - | 270 | WP_040122444.1 | DUF1778 domain-containing protein | Antitoxin |
IX92_RS27690 | 107770..108192 | - | 423 | WP_043011729.1 | GNAT family N-acetyltransferase | - |
IX92_RS27695 | 108341..108490 | - | 150 | Protein_112 | NUDIX hydrolase | - |
IX92_RS27700 | 108652..109077 | - | 426 | WP_019274862.1 | hypothetical protein | - |
IX92_RS27705 | 109129..109899 | - | 771 | WP_043011732.1 | GNAT family N-acetyltransferase | - |
IX92_RS27710 | 110002..110370 | - | 369 | WP_043011734.1 | hypothetical protein | - |
IX92_RS27715 | 110433..110954 | - | 522 | WP_043011735.1 | hypothetical protein | - |
IX92_RS27720 | 111056..111445 | - | 390 | WP_144382890.1 | hypothetical protein | - |
IX92_RS27725 | 111461..111931 | - | 471 | WP_043011740.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..319400 | 319400 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 188 a.a. Molecular weight: 20984.44 Da Isoelectric Point: 9.6169
>T49327 WP_043011727.1 NZ_CP009620:c107297-106734 [Vibrio coralliilyticus]
VSWGNEFVELSKSMHDRSSFDCGESELNTFIKTLAAKHMQAGISRTMVLPSSQPLLNRKYAICAFYSVAPSSISRESLPA
KLAKTLPRYPIPVFLLAQLAVHKEFHGSGLGKISLIRALKYLWGVNHHMRAYAIVVDCLTDSAQAFYTKFGFEVLCEHNG
RIRMFLPMKTVEQLFSPKATNITKDDV
VSWGNEFVELSKSMHDRSSFDCGESELNTFIKTLAAKHMQAGISRTMVLPSSQPLLNRKYAICAFYSVAPSSISRESLPA
KLAKTLPRYPIPVFLLAQLAVHKEFHGSGLGKISLIRALKYLWGVNHHMRAYAIVVDCLTDSAQAFYTKFGFEVLCEHNG
RIRMFLPMKTVEQLFSPKATNITKDDV
Download Length: 564 bp
>T49327 NZ_CP009620:c107297-106734 [Vibrio coralliilyticus]
GTGAGTTGGGGAAACGAGTTCGTTGAACTTAGTAAATCCATGCATGATCGCAGCTCATTTGATTGTGGTGAGTCAGAGTT
AAATACGTTTATTAAAACGCTAGCAGCAAAACACATGCAAGCAGGTATCAGCCGAACGATGGTTTTACCAAGCTCTCAGC
CACTGCTTAATCGAAAGTATGCTATTTGCGCTTTTTACAGTGTTGCTCCTAGTTCAATCAGTCGTGAATCTTTACCTGCT
AAGTTAGCGAAAACGTTACCTAGATATCCCATCCCCGTTTTTTTATTAGCTCAGCTAGCGGTGCATAAAGAATTTCATGG
CTCAGGATTAGGGAAAATCAGTTTAATTCGAGCGTTAAAGTATCTTTGGGGAGTGAATCACCACATGAGAGCTTATGCCA
TTGTTGTGGACTGCCTTACCGACTCCGCACAAGCATTCTATACTAAGTTTGGCTTTGAGGTTTTGTGTGAGCATAATGGG
CGTATACGTATGTTTTTACCAATGAAAACGGTAGAACAGCTTTTTAGTCCAAAGGCCACGAATATCACAAAAGATGATGT
CTAG
GTGAGTTGGGGAAACGAGTTCGTTGAACTTAGTAAATCCATGCATGATCGCAGCTCATTTGATTGTGGTGAGTCAGAGTT
AAATACGTTTATTAAAACGCTAGCAGCAAAACACATGCAAGCAGGTATCAGCCGAACGATGGTTTTACCAAGCTCTCAGC
CACTGCTTAATCGAAAGTATGCTATTTGCGCTTTTTACAGTGTTGCTCCTAGTTCAATCAGTCGTGAATCTTTACCTGCT
AAGTTAGCGAAAACGTTACCTAGATATCCCATCCCCGTTTTTTTATTAGCTCAGCTAGCGGTGCATAAAGAATTTCATGG
CTCAGGATTAGGGAAAATCAGTTTAATTCGAGCGTTAAAGTATCTTTGGGGAGTGAATCACCACATGAGAGCTTATGCCA
TTGTTGTGGACTGCCTTACCGACTCCGCACAAGCATTCTATACTAAGTTTGGCTTTGAGGTTTTGTGTGAGCATAATGGG
CGTATACGTATGTTTTTACCAATGAAAACGGTAGAACAGCTTTTTAGTCCAAAGGCCACGAATATCACAAAAGATGATGT
CTAG
Antitoxin
Download Length: 90 a.a. Molecular weight: 9839.34 Da Isoelectric Point: 4.5482
>AT49327 WP_040122444.1 NZ_CP009620:c107563-107294 [Vibrio coralliilyticus]
MATARLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDATQVIEQHESIVVKESVFDEFMMACDKAKAPNQALLDAA
KLTNESGIK
MATARLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDATQVIEQHESIVVKESVFDEFMMACDKAKAPNQALLDAA
KLTNESGIK
Download Length: 270 bp
>AT49327 NZ_CP009620:c107563-107294 [Vibrio coralliilyticus]
ATGGCAACAGCACGTTTAGATATTCGCCTTGACGAAGAGATCAAAGCAAAAGCGGAGAAAGCATCGGCTTTACTGGGTCT
TAAAAGCCTTACTGAGTATGTAGTAAGACTTATGGATGAAGACGCAACTCAGGTAATTGAACAGCACGAAAGTATCGTAG
TCAAAGAGAGTGTCTTCGATGAATTCATGATGGCATGTGACAAAGCAAAGGCTCCCAATCAAGCTTTACTTGATGCAGCG
AAATTGACCAATGAGAGTGGCATCAAGTGA
ATGGCAACAGCACGTTTAGATATTCGCCTTGACGAAGAGATCAAAGCAAAAGCGGAGAAAGCATCGGCTTTACTGGGTCT
TAAAAGCCTTACTGAGTATGTAGTAAGACTTATGGATGAAGACGCAACTCAGGTAATTGAACAGCACGAAAGTATCGTAG
TCAAAGAGAGTGTCTTCGATGAATTCATGATGGCATGTGACAAAGCAAAGGCTCCCAATCAAGCTTTACTTGATGCAGCG
AAATTGACCAATGAGAGTGGCATCAAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7Y4BPZ8 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7Y3YYU7 |