49327

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) /DUF1778(antitoxin)
Location 106734..107563 Replicon plasmid p319
Accession NZ_CP009620
Organism Vibrio coralliilyticus strain RE98

Toxin (Protein)


Gene name - Uniprot ID A0A7Y4BPZ8
Locus tag IX92_RS27680 Protein ID WP_043011727.1
Coordinates 106734..107297 (-) Length 188 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A7Y3YYU7
Locus tag IX92_RS27685 Protein ID WP_040122444.1
Coordinates 107294..107563 (-) Length 90 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IX92_RS27670 101777..102745 - 969 WP_043011721.1 hypothetical protein -
IX92_RS27675 103214..105307 - 2094 WP_043011724.1 TonB-dependent siderophore receptor -
IX92_RS27680 106734..107297 - 564 WP_043011727.1 GNAT family N-acetyltransferase Toxin
IX92_RS27685 107294..107563 - 270 WP_040122444.1 DUF1778 domain-containing protein Antitoxin
IX92_RS27690 107770..108192 - 423 WP_043011729.1 GNAT family N-acetyltransferase -
IX92_RS27695 108341..108490 - 150 Protein_112 NUDIX hydrolase -
IX92_RS27700 108652..109077 - 426 WP_019274862.1 hypothetical protein -
IX92_RS27705 109129..109899 - 771 WP_043011732.1 GNAT family N-acetyltransferase -
IX92_RS27710 110002..110370 - 369 WP_043011734.1 hypothetical protein -
IX92_RS27715 110433..110954 - 522 WP_043011735.1 hypothetical protein -
IX92_RS27720 111056..111445 - 390 WP_144382890.1 hypothetical protein -
IX92_RS27725 111461..111931 - 471 WP_043011740.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..319400 319400


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(97-153)

Antitoxin

(5-81)


Sequences


Toxin        


Download         Length: 188 a.a.        Molecular weight: 20984.44 Da        Isoelectric Point: 9.6169

>T49327 WP_043011727.1 NZ_CP009620:c107297-106734 [Vibrio coralliilyticus]
VSWGNEFVELSKSMHDRSSFDCGESELNTFIKTLAAKHMQAGISRTMVLPSSQPLLNRKYAICAFYSVAPSSISRESLPA
KLAKTLPRYPIPVFLLAQLAVHKEFHGSGLGKISLIRALKYLWGVNHHMRAYAIVVDCLTDSAQAFYTKFGFEVLCEHNG
RIRMFLPMKTVEQLFSPKATNITKDDV

Download         Length: 564 bp

>T49327 NZ_CP009620:c107297-106734 [Vibrio coralliilyticus]
GTGAGTTGGGGAAACGAGTTCGTTGAACTTAGTAAATCCATGCATGATCGCAGCTCATTTGATTGTGGTGAGTCAGAGTT
AAATACGTTTATTAAAACGCTAGCAGCAAAACACATGCAAGCAGGTATCAGCCGAACGATGGTTTTACCAAGCTCTCAGC
CACTGCTTAATCGAAAGTATGCTATTTGCGCTTTTTACAGTGTTGCTCCTAGTTCAATCAGTCGTGAATCTTTACCTGCT
AAGTTAGCGAAAACGTTACCTAGATATCCCATCCCCGTTTTTTTATTAGCTCAGCTAGCGGTGCATAAAGAATTTCATGG
CTCAGGATTAGGGAAAATCAGTTTAATTCGAGCGTTAAAGTATCTTTGGGGAGTGAATCACCACATGAGAGCTTATGCCA
TTGTTGTGGACTGCCTTACCGACTCCGCACAAGCATTCTATACTAAGTTTGGCTTTGAGGTTTTGTGTGAGCATAATGGG
CGTATACGTATGTTTTTACCAATGAAAACGGTAGAACAGCTTTTTAGTCCAAAGGCCACGAATATCACAAAAGATGATGT
CTAG

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9839.34 Da        Isoelectric Point: 4.5482

>AT49327 WP_040122444.1 NZ_CP009620:c107563-107294 [Vibrio coralliilyticus]
MATARLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDATQVIEQHESIVVKESVFDEFMMACDKAKAPNQALLDAA
KLTNESGIK

Download         Length: 270 bp

>AT49327 NZ_CP009620:c107563-107294 [Vibrio coralliilyticus]
ATGGCAACAGCACGTTTAGATATTCGCCTTGACGAAGAGATCAAAGCAAAAGCGGAGAAAGCATCGGCTTTACTGGGTCT
TAAAAGCCTTACTGAGTATGTAGTAAGACTTATGGATGAAGACGCAACTCAGGTAATTGAACAGCACGAAAGTATCGTAG
TCAAAGAGAGTGTCTTCGATGAATTCATGATGGCATGTGACAAAGCAAAGGCTCCCAATCAAGCTTTACTTGATGCAGCG
AAATTGACCAATGAGAGTGGCATCAAGTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A7Y4BPZ8


Antitoxin

Source ID Structure
AlphaFold DB A0A7Y3YYU7

References