Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /SpoIISA(toxin)
Location 136220..137195 Replicon chromosome
Accession NZ_CP009600
Organism Bacillus thuringiensis strain HD571

Toxin (Protein)


Gene name spoIISA Uniprot ID C2NHW3
Locus tag BF32_RS01095 Protein ID WP_002002796.1
Coordinates 136220..136957 (+) Length 246 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID R8HWP4
Locus tag BF32_RS01100 Protein ID WP_000588712.1
Coordinates 137070..137195 (+) Length 42 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BF32_RS01070 131712..132413 + 702 WP_001294994.1 hypothetical protein -
BF32_RS01075 132541..133425 + 885 WP_000795513.1 hypothetical protein -
BF32_RS01080 133718..134537 - 820 Protein_139 alpha-keto acid decarboxylase family protein -
BF32_RS01085 134644..135126 + 483 WP_000191909.1 MarR family winged helix-turn-helix transcriptional regulator -
BF32_RS01090 135294..136031 + 738 WP_000594157.1 2,3-diphosphoglycerate-dependent phosphoglycerate mutase -
BF32_RS01095 136220..136957 + 738 WP_002002796.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
BF32_RS01100 137070..137195 + 126 WP_000588712.1 hypothetical protein Antitoxin
BF32_RS01110 137469..137750 - 282 WP_001041559.1 hypothetical protein -
BF32_RS01115 138030..138266 - 237 WP_001021690.1 hypothetical protein -
BF32_RS29515 138605..138781 + 177 WP_000852618.1 hypothetical protein -
BF32_RS01125 138925..140394 + 1470 WP_000287551.1 beta-Ala-His dipeptidase -
BF32_RS01130 140980..141450 - 471 WP_000771846.1 DUF5065 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(9-243)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 246 a.a.        Molecular weight: 28283.98 Da        Isoelectric Point: 8.2998

>T49310 WP_002002796.1 NZ_CP009600:136220-136957 [Bacillus thuringiensis]
VISNIRIGLFILAIVFLVLVFFYWKNEELYEEKKQRIRKTWYGLFIVSVTVYFMIKGIDLTLWKNLLMFTAMVIFVDIAF
ILTPNISEIWGAKFSDIGKTVQSIKRSLIASKARGEIYTTIIQNVNAAVFGTMEWHTEEEYTKSLNAFLDSYGEKIGAKI
VVFEAAKELNTTFRGIRSQFSIIVPFEHIEQLNEQKAVQVENVGIIPAKIVSDVFIVIDGKKNNLQDRDFENVYNLTIHH
SYFSK

Download         Length: 738 bp

>T49310 NZ_CP009600:136220-136957 [Bacillus thuringiensis]
GTGATCTCTAACATTCGAATCGGCTTATTTATTTTAGCAATCGTTTTTCTAGTACTTGTTTTCTTTTATTGGAAAAACGA
AGAGTTGTACGAGGAGAAGAAGCAACGTATTAGAAAGACTTGGTATGGATTGTTTATAGTATCAGTCACCGTGTATTTCA
TGATAAAAGGAATTGATTTAACCCTCTGGAAAAATCTTTTAATGTTCACTGCAATGGTTATTTTCGTTGATATTGCATTT
ATTTTAACACCTAATATTTCAGAGATATGGGGAGCGAAATTTAGCGATATCGGCAAGACTGTTCAATCGATAAAACGGTC
ATTAATTGCTTCTAAAGCAAGAGGAGAAATATACACAACAATTATTCAAAATGTGAATGCAGCAGTATTTGGTACGATGG
AATGGCATACGGAAGAAGAATATACAAAAAGTTTAAACGCATTTTTAGATTCATATGGGGAAAAGATTGGGGCGAAGATT
GTTGTATTTGAAGCAGCAAAGGAATTAAATACAACCTTTCGCGGTATCCGCTCGCAATTTAGTATTATCGTTCCGTTTGA
ACACATTGAGCAATTGAATGAGCAGAAAGCGGTGCAAGTAGAAAATGTCGGAATTATACCAGCAAAAATAGTGAGTGATG
TTTTTATTGTTATTGATGGGAAGAAAAATAATCTGCAAGATCGGGATTTTGAAAATGTATATAATTTAACAATACATCAT
AGTTATTTTAGTAAATAA

Antitoxin


Download         Length: 42 a.a.        Molecular weight: 4938.34 Da        Isoelectric Point: 3.9150

>AT49310 WP_000588712.1 NZ_CP009600:137070-137195 [Bacillus thuringiensis]
VIKDYDNDFFKEDNEDTTDFSLIKGDTLQQVEELEEELKRK

Download         Length: 126 bp

>AT49310 NZ_CP009600:137070-137195 [Bacillus thuringiensis]
GTGATAAAAGATTATGACAATGATTTTTTTAAAGAAGATAATGAAGATACAACAGATTTCTCGTTAATAAAAGGAGATAC
GTTACAGCAAGTAGAAGAGTTAGAAGAAGAGTTAAAAAGAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7D3YFM0

Antitoxin

Source ID Structure
AlphaFold DB A0A366GQT1

References