Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelE-RHH
Location 19246..19793 Replicon plasmid pCVM22462
Accession NZ_CP009566
Organism Salmonella enterica subsp. enterica serovar Newport str. CVM 22462

Toxin (Protein)


Gene name parE Uniprot ID E9LLH3
Locus tag SEEN462_RS00125 Protein ID WP_000969996.1
Coordinates 19246..19527 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID K4JYR0
Locus tag SEEN462_RS00130 Protein ID WP_000079928.1
Coordinates 19524..19793 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SEEN462_RS00105 15873..16475 + 603 WP_000517689.1 hypothetical protein -
SEEN462_RS00110 16531..17025 + 495 WP_023278058.1 hypothetical protein -
SEEN462_RS00115 17768..18241 - 474 WP_001334658.1 hypothetical protein -
SEEN462_RS00120 18358..19206 - 849 WP_001057996.1 3'-5' exonuclease -
SEEN462_RS00125 19246..19527 - 282 WP_000969996.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
SEEN462_RS00130 19524..19793 - 270 WP_000079928.1 hypothetical protein Antitoxin
SEEN462_RS00135 20702..21733 - 1032 WP_000907874.1 replication initiation protein -
SEEN462_RS25365 22706..22969 + 264 WP_001324596.1 ash family protein -
SEEN462_RS00150 22887..23174 + 288 WP_000074849.1 conjugal transfer protein TraA -
SEEN462_RS00155 23616..24149 + 534 WP_001303319.1 transcription termination factor NusG -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..94725 94725


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 13852.62 Da        Isoelectric Point: 5.5500

>T49286 WP_000969996.1 NZ_CP009566:c19527-19246 [Salmonella enterica subsp. enterica serovar Newport str. CVM 22462]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFF

Download         Length: 282 bp

>T49286 NZ_CP009566:c19527-19246 [Salmonella enterica subsp. enterica serovar Newport str. CVM 22462]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 13263.91 Da        Isoelectric Point: 5.5500

>AT49286 WP_000079928.1 NZ_CP009566:c19793-19524 [Salmonella enterica subsp. enterica serovar Newport str. CVM 22462]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFF

Download         Length: 270 bp

>AT49286 NZ_CP009566:c19793-19524 [Salmonella enterica subsp. enterica serovar Newport str. CVM 22462]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB E9LLH3

Antitoxin

Source ID Structure
AlphaFold DB A0A5W2J4D0

References