Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | pmenTA/darT(toxin) |
Location | 2639838..2641558 | Replicon | chromosome |
Accession | NZ_CP009539 | ||
Organism | Yersinia ruckeri strain YRB |
Toxin (Protein)
Gene name | pmenT | Uniprot ID | - |
Locus tag | BD65_RS11915 | Protein ID | WP_042527226.1 |
Coordinates | 2640902..2641558 (-) | Length | 219 a.a. |
Antitoxin (Protein)
Gene name | pmenA | Uniprot ID | - |
Locus tag | BD65_RS11910 | Protein ID | WP_042527224.1 |
Coordinates | 2639838..2640905 (-) | Length | 356 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BD65_RS11895 | 2635274..2635582 | - | 309 | WP_042527219.1 | transposase | - |
BD65_RS11900 | 2636006..2636722 | - | 717 | WP_042527221.1 | M48 family metallopeptidase | - |
BD65_RS11905 | 2636722..2639817 | - | 3096 | WP_042527223.1 | HsdR family type I site-specific deoxyribonuclease | - |
BD65_RS11910 | 2639838..2640905 | - | 1068 | WP_042527224.1 | macro domain-containing protein | Antitoxin |
BD65_RS11915 | 2640902..2641558 | - | 657 | WP_042527226.1 | DUF4433 domain-containing protein | Toxin |
BD65_RS11920 | 2641548..2642138 | - | 591 | WP_042527228.1 | DUF4433 domain-containing protein | - |
BD65_RS11925 | 2642143..2643540 | - | 1398 | WP_042527230.1 | restriction endonuclease subunit S | - |
BD65_RS11930 | 2643540..2645977 | - | 2438 | Protein_2329 | type I restriction-modification system subunit M | - |
BD65_RS11935 | 2646017..2646256 | - | 240 | WP_012543063.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 2624307..2653575 | 29268 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 219 a.a. Molecular weight: 25236.70 Da Isoelectric Point: 6.9653
>T49241 WP_042527226.1 NZ_CP009539:c2641558-2640902 [Yersinia ruckeri]
VAYDYSTSLNPEKALIWRIVHRDNIPWILDNGLHCGNSPVQAENWINIGNPELIDKRAEHLVPIGTGGTLHDYVPFYFTP
FSPMLMNIRSGRGGIKQRPNEEIVILVSSLRHVAAQNIPFVFTDSHAYYNLANYYTDLNNLHRIDWPILQARDFRRDQDD
LGKFERYQAEALIWKHCPISLLGGMICYNDGVRLQLEQWLSQRNLSMPVHARAGWYFS
VAYDYSTSLNPEKALIWRIVHRDNIPWILDNGLHCGNSPVQAENWINIGNPELIDKRAEHLVPIGTGGTLHDYVPFYFTP
FSPMLMNIRSGRGGIKQRPNEEIVILVSSLRHVAAQNIPFVFTDSHAYYNLANYYTDLNNLHRIDWPILQARDFRRDQDD
LGKFERYQAEALIWKHCPISLLGGMICYNDGVRLQLEQWLSQRNLSMPVHARAGWYFS
Download Length: 657 bp
>T49241 NZ_CP009539:c2641558-2640902 [Yersinia ruckeri]
GTGGCCTATGACTACAGTACTAGCCTCAACCCGGAAAAAGCCCTGATCTGGCGCATTGTCCATCGGGACAATATCCCATG
GATACTGGACAACGGCCTGCACTGCGGAAACAGTCCGGTGCAGGCGGAAAACTGGATTAATATCGGCAACCCGGAGCTTA
TCGACAAACGTGCCGAACATCTGGTGCCTATCGGAACAGGAGGAACGCTGCATGACTATGTGCCGTTTTACTTTACTCCT
TTCTCGCCGATGCTGATGAATATTCGCAGCGGGCGTGGCGGCATTAAGCAGCGCCCCAATGAGGAAATCGTTATTCTGGT
CAGCAGCCTGCGACACGTGGCGGCGCAGAACATTCCCTTCGTGTTTACCGACAGCCACGCCTACTATAATCTGGCGAATT
ACTATACCGATCTAAACAATCTGCATCGGATCGACTGGCCAATCTTACAAGCACGGGATTTCCGTCGCGATCAGGATGAT
CTTGGCAAGTTTGAACGCTATCAAGCTGAGGCATTAATCTGGAAGCACTGCCCAATCTCACTGCTGGGCGGGATGATTTG
TTACAACGATGGCGTCAGGTTACAATTAGAGCAGTGGCTGTCGCAACGCAATCTGTCAATGCCCGTTCACGCACGGGCCG
GGTGGTACTTCTCATGA
GTGGCCTATGACTACAGTACTAGCCTCAACCCGGAAAAAGCCCTGATCTGGCGCATTGTCCATCGGGACAATATCCCATG
GATACTGGACAACGGCCTGCACTGCGGAAACAGTCCGGTGCAGGCGGAAAACTGGATTAATATCGGCAACCCGGAGCTTA
TCGACAAACGTGCCGAACATCTGGTGCCTATCGGAACAGGAGGAACGCTGCATGACTATGTGCCGTTTTACTTTACTCCT
TTCTCGCCGATGCTGATGAATATTCGCAGCGGGCGTGGCGGCATTAAGCAGCGCCCCAATGAGGAAATCGTTATTCTGGT
CAGCAGCCTGCGACACGTGGCGGCGCAGAACATTCCCTTCGTGTTTACCGACAGCCACGCCTACTATAATCTGGCGAATT
ACTATACCGATCTAAACAATCTGCATCGGATCGACTGGCCAATCTTACAAGCACGGGATTTCCGTCGCGATCAGGATGAT
CTTGGCAAGTTTGAACGCTATCAAGCTGAGGCATTAATCTGGAAGCACTGCCCAATCTCACTGCTGGGCGGGATGATTTG
TTACAACGATGGCGTCAGGTTACAATTAGAGCAGTGGCTGTCGCAACGCAATCTGTCAATGCCCGTTCACGCACGGGCCG
GGTGGTACTTCTCATGA
Antitoxin
Download Length: 356 a.a. Molecular weight: 40705.97 Da Isoelectric Point: 6.5048
>AT49241 WP_042527224.1 NZ_CP009539:c2640905-2639838 [Yersinia ruckeri]
MMTYTQGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPDNMKAYALACKQKQVMTGKMFITETSELMGPRWIVNFPTK
QHWRADSRMEWIEDGLQDLRRFLIEEKVQSIAIPPLGAGNGGLNWSDVRARIESALGDLRGTEILIYEPTEKYQNVAKST
GVKKLTPARAMIAELVRRYSVLGMECSLLEIQKLAWLLQRAIELHQQEDVLKLRFEAHNYGPFSPNLNHLLNALDGTYLK
AEKRIPDSQPLDVIWFNDREKEHVNLWLNNEAKKWLPALEQVSQLIDGFESPFGLELLATVDWLLTRGECQPTLDSVKEG
LHQWPAGERWASRKMKLFDDNHLQFAINRVMEFHC
MMTYTQGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPDNMKAYALACKQKQVMTGKMFITETSELMGPRWIVNFPTK
QHWRADSRMEWIEDGLQDLRRFLIEEKVQSIAIPPLGAGNGGLNWSDVRARIESALGDLRGTEILIYEPTEKYQNVAKST
GVKKLTPARAMIAELVRRYSVLGMECSLLEIQKLAWLLQRAIELHQQEDVLKLRFEAHNYGPFSPNLNHLLNALDGTYLK
AEKRIPDSQPLDVIWFNDREKEHVNLWLNNEAKKWLPALEQVSQLIDGFESPFGLELLATVDWLLTRGECQPTLDSVKEG
LHQWPAGERWASRKMKLFDDNHLQFAINRVMEFHC
Download Length: 1068 bp
>AT49241 NZ_CP009539:c2640905-2639838 [Yersinia ruckeri]
ATGATGACATATACACAAGGCAATTTACTGGACGCGCCCGTGGAAGCACTGGTGAATACGGTTAATACCGTCGGTGTCAT
GGGTAAAGGCATCGCGCTAATGTTCAAAGAGCGCTTCCCCGACAACATGAAAGCCTATGCTCTCGCCTGCAAACAAAAGC
AGGTCATGACCGGCAAGATGTTTATTACCGAAACCAGCGAGCTGATGGGGCCGCGCTGGATCGTCAACTTCCCAACTAAG
CAGCACTGGCGCGCCGACTCCCGCATGGAGTGGATTGAAGACGGCTTGCAGGACCTGCGCCGCTTTCTGATCGAAGAGAA
AGTGCAGTCCATAGCCATTCCTCCACTGGGCGCAGGCAATGGTGGCCTGAACTGGTCGGATGTCCGGGCGCGGATTGAAT
CTGCGCTGGGTGACCTTCGGGGCACAGAAATCCTGATTTATGAGCCTACCGAAAAATACCAGAACGTCGCCAAGAGCACC
GGAGTAAAAAAGCTCACACCCGCCAGAGCGATGATCGCTGAACTAGTGCGCCGCTACTCGGTGCTGGGCATGGAGTGCAG
CCTGCTGGAAATCCAGAAGCTGGCATGGCTGTTACAACGCGCTATTGAACTGCACCAGCAGGAGGATGTGCTAAAACTAC
GCTTTGAGGCGCACAATTACGGTCCCTTCTCCCCCAACCTGAACCATCTGCTTAACGCGCTGGACGGCACCTATCTGAAA
GCCGAGAAACGCATCCCGGACAGCCAGCCGCTAGACGTGATCTGGTTTAACGATCGGGAAAAAGAACACGTCAACCTCTG
GCTGAACAACGAGGCTAAAAAGTGGCTACCGGCGCTTGAGCAGGTCAGTCAGTTGATTGACGGCTTTGAATCACCGTTTG
GTCTGGAGCTGCTAGCGACCGTTGACTGGCTGCTGACCCGAGGAGAATGCCAGCCCACGCTGGATTCCGTAAAAGAGGGG
CTGCACCAATGGCCTGCGGGTGAACGCTGGGCCAGCCGTAAGATGAAGCTGTTTGATGATAATCATCTTCAATTCGCCAT
AAACCGCGTGATGGAGTTCCATTGCTGA
ATGATGACATATACACAAGGCAATTTACTGGACGCGCCCGTGGAAGCACTGGTGAATACGGTTAATACCGTCGGTGTCAT
GGGTAAAGGCATCGCGCTAATGTTCAAAGAGCGCTTCCCCGACAACATGAAAGCCTATGCTCTCGCCTGCAAACAAAAGC
AGGTCATGACCGGCAAGATGTTTATTACCGAAACCAGCGAGCTGATGGGGCCGCGCTGGATCGTCAACTTCCCAACTAAG
CAGCACTGGCGCGCCGACTCCCGCATGGAGTGGATTGAAGACGGCTTGCAGGACCTGCGCCGCTTTCTGATCGAAGAGAA
AGTGCAGTCCATAGCCATTCCTCCACTGGGCGCAGGCAATGGTGGCCTGAACTGGTCGGATGTCCGGGCGCGGATTGAAT
CTGCGCTGGGTGACCTTCGGGGCACAGAAATCCTGATTTATGAGCCTACCGAAAAATACCAGAACGTCGCCAAGAGCACC
GGAGTAAAAAAGCTCACACCCGCCAGAGCGATGATCGCTGAACTAGTGCGCCGCTACTCGGTGCTGGGCATGGAGTGCAG
CCTGCTGGAAATCCAGAAGCTGGCATGGCTGTTACAACGCGCTATTGAACTGCACCAGCAGGAGGATGTGCTAAAACTAC
GCTTTGAGGCGCACAATTACGGTCCCTTCTCCCCCAACCTGAACCATCTGCTTAACGCGCTGGACGGCACCTATCTGAAA
GCCGAGAAACGCATCCCGGACAGCCAGCCGCTAGACGTGATCTGGTTTAACGATCGGGAAAAAGAACACGTCAACCTCTG
GCTGAACAACGAGGCTAAAAAGTGGCTACCGGCGCTTGAGCAGGTCAGTCAGTTGATTGACGGCTTTGAATCACCGTTTG
GTCTGGAGCTGCTAGCGACCGTTGACTGGCTGCTGACCCGAGGAGAATGCCAGCCCACGCTGGATTCCGTAAAAGAGGGG
CTGCACCAATGGCCTGCGGGTGAACGCTGGGCCAGCCGTAAGATGAAGCTGTTTGATGATAATCATCTTCAATTCGCCAT
AAACCGCGTGATGGAGTTCCATTGCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|
Antitoxin
Source | ID | Structure |
---|