Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 2639838..2641558 Replicon chromosome
Accession NZ_CP009539
Organism Yersinia ruckeri strain YRB

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag BD65_RS11915 Protein ID WP_042527226.1
Coordinates 2640902..2641558 (-) Length 219 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag BD65_RS11910 Protein ID WP_042527224.1
Coordinates 2639838..2640905 (-) Length 356 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BD65_RS11895 2635274..2635582 - 309 WP_042527219.1 transposase -
BD65_RS11900 2636006..2636722 - 717 WP_042527221.1 M48 family metallopeptidase -
BD65_RS11905 2636722..2639817 - 3096 WP_042527223.1 HsdR family type I site-specific deoxyribonuclease -
BD65_RS11910 2639838..2640905 - 1068 WP_042527224.1 macro domain-containing protein Antitoxin
BD65_RS11915 2640902..2641558 - 657 WP_042527226.1 DUF4433 domain-containing protein Toxin
BD65_RS11920 2641548..2642138 - 591 WP_042527228.1 DUF4433 domain-containing protein -
BD65_RS11925 2642143..2643540 - 1398 WP_042527230.1 restriction endonuclease subunit S -
BD65_RS11930 2643540..2645977 - 2438 Protein_2329 type I restriction-modification system subunit M -
BD65_RS11935 2646017..2646256 - 240 WP_012543063.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2624307..2653575 29268


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(17-217)

Antitoxin

Macro domain

(18-129)


Sequences

Toxin        


Download         Length: 219 a.a.        Molecular weight: 25236.70 Da        Isoelectric Point: 6.9653

>T49241 WP_042527226.1 NZ_CP009539:c2641558-2640902 [Yersinia ruckeri]
VAYDYSTSLNPEKALIWRIVHRDNIPWILDNGLHCGNSPVQAENWINIGNPELIDKRAEHLVPIGTGGTLHDYVPFYFTP
FSPMLMNIRSGRGGIKQRPNEEIVILVSSLRHVAAQNIPFVFTDSHAYYNLANYYTDLNNLHRIDWPILQARDFRRDQDD
LGKFERYQAEALIWKHCPISLLGGMICYNDGVRLQLEQWLSQRNLSMPVHARAGWYFS

Download         Length: 657 bp

>T49241 NZ_CP009539:c2641558-2640902 [Yersinia ruckeri]
GTGGCCTATGACTACAGTACTAGCCTCAACCCGGAAAAAGCCCTGATCTGGCGCATTGTCCATCGGGACAATATCCCATG
GATACTGGACAACGGCCTGCACTGCGGAAACAGTCCGGTGCAGGCGGAAAACTGGATTAATATCGGCAACCCGGAGCTTA
TCGACAAACGTGCCGAACATCTGGTGCCTATCGGAACAGGAGGAACGCTGCATGACTATGTGCCGTTTTACTTTACTCCT
TTCTCGCCGATGCTGATGAATATTCGCAGCGGGCGTGGCGGCATTAAGCAGCGCCCCAATGAGGAAATCGTTATTCTGGT
CAGCAGCCTGCGACACGTGGCGGCGCAGAACATTCCCTTCGTGTTTACCGACAGCCACGCCTACTATAATCTGGCGAATT
ACTATACCGATCTAAACAATCTGCATCGGATCGACTGGCCAATCTTACAAGCACGGGATTTCCGTCGCGATCAGGATGAT
CTTGGCAAGTTTGAACGCTATCAAGCTGAGGCATTAATCTGGAAGCACTGCCCAATCTCACTGCTGGGCGGGATGATTTG
TTACAACGATGGCGTCAGGTTACAATTAGAGCAGTGGCTGTCGCAACGCAATCTGTCAATGCCCGTTCACGCACGGGCCG
GGTGGTACTTCTCATGA

Antitoxin


Download         Length: 356 a.a.        Molecular weight: 40705.97 Da        Isoelectric Point: 6.5048

>AT49241 WP_042527224.1 NZ_CP009539:c2640905-2639838 [Yersinia ruckeri]
MMTYTQGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPDNMKAYALACKQKQVMTGKMFITETSELMGPRWIVNFPTK
QHWRADSRMEWIEDGLQDLRRFLIEEKVQSIAIPPLGAGNGGLNWSDVRARIESALGDLRGTEILIYEPTEKYQNVAKST
GVKKLTPARAMIAELVRRYSVLGMECSLLEIQKLAWLLQRAIELHQQEDVLKLRFEAHNYGPFSPNLNHLLNALDGTYLK
AEKRIPDSQPLDVIWFNDREKEHVNLWLNNEAKKWLPALEQVSQLIDGFESPFGLELLATVDWLLTRGECQPTLDSVKEG
LHQWPAGERWASRKMKLFDDNHLQFAINRVMEFHC

Download         Length: 1068 bp

>AT49241 NZ_CP009539:c2640905-2639838 [Yersinia ruckeri]
ATGATGACATATACACAAGGCAATTTACTGGACGCGCCCGTGGAAGCACTGGTGAATACGGTTAATACCGTCGGTGTCAT
GGGTAAAGGCATCGCGCTAATGTTCAAAGAGCGCTTCCCCGACAACATGAAAGCCTATGCTCTCGCCTGCAAACAAAAGC
AGGTCATGACCGGCAAGATGTTTATTACCGAAACCAGCGAGCTGATGGGGCCGCGCTGGATCGTCAACTTCCCAACTAAG
CAGCACTGGCGCGCCGACTCCCGCATGGAGTGGATTGAAGACGGCTTGCAGGACCTGCGCCGCTTTCTGATCGAAGAGAA
AGTGCAGTCCATAGCCATTCCTCCACTGGGCGCAGGCAATGGTGGCCTGAACTGGTCGGATGTCCGGGCGCGGATTGAAT
CTGCGCTGGGTGACCTTCGGGGCACAGAAATCCTGATTTATGAGCCTACCGAAAAATACCAGAACGTCGCCAAGAGCACC
GGAGTAAAAAAGCTCACACCCGCCAGAGCGATGATCGCTGAACTAGTGCGCCGCTACTCGGTGCTGGGCATGGAGTGCAG
CCTGCTGGAAATCCAGAAGCTGGCATGGCTGTTACAACGCGCTATTGAACTGCACCAGCAGGAGGATGTGCTAAAACTAC
GCTTTGAGGCGCACAATTACGGTCCCTTCTCCCCCAACCTGAACCATCTGCTTAACGCGCTGGACGGCACCTATCTGAAA
GCCGAGAAACGCATCCCGGACAGCCAGCCGCTAGACGTGATCTGGTTTAACGATCGGGAAAAAGAACACGTCAACCTCTG
GCTGAACAACGAGGCTAAAAAGTGGCTACCGGCGCTTGAGCAGGTCAGTCAGTTGATTGACGGCTTTGAATCACCGTTTG
GTCTGGAGCTGCTAGCGACCGTTGACTGGCTGCTGACCCGAGGAGAATGCCAGCCCACGCTGGATTCCGTAAAAGAGGGG
CTGCACCAATGGCCTGCGGGTGAACGCTGGGCCAGCCGTAAGATGAAGCTGTTTGATGATAATCATCTTCAATTCGCCAT
AAACCGCGTGATGGAGTTCCATTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References