Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 1435321..1435922 Replicon chromosome
Accession NZ_CP009539
Organism Yersinia ruckeri strain YRB

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag BD65_RS06525 Protein ID WP_042525901.1
Coordinates 1435566..1435922 (+) Length 119 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag BD65_RS06520 Protein ID WP_042525899.1
Coordinates 1435321..1435572 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BD65_RS06490 1430846..1431172 - 327 WP_038240973.1 YggL family protein -
BD65_RS06495 1431172..1431891 - 720 WP_038240971.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -
BD65_RS06500 1432117..1433217 + 1101 WP_042525898.1 A/G-specific adenine glycosylase -
BD65_RS06505 1433214..1433486 + 273 WP_038240969.1 oxidative damage protection protein -
BD65_RS06510 1433544..1434620 + 1077 WP_004719291.1 membrane-bound lytic murein transglycosylase MltC -
BD65_RS16855 1435024..1435161 + 138 Protein_1278 transposase -
BD65_RS06520 1435321..1435572 + 252 WP_042525899.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
BD65_RS06525 1435566..1435922 + 357 WP_042525901.1 type II toxin-antitoxin system ChpB family toxin Toxin
BD65_RS06530 1436483..1436800 - 318 WP_173425062.1 YmgD family protein -
BD65_RS06535 1436823..1437191 - 369 WP_042525906.1 hypothetical protein -
BD65_RS06540 1437438..1437793 + 356 Protein_1283 hypothetical protein -
BD65_RS06545 1437790..1438722 - 933 WP_042525908.1 6-phosphofructokinase II -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(9-104)

Antitoxin

SpoVT-AbrB domain

(6-49)


Sequences

Toxin        


Download         Length: 119 a.a.        Molecular weight: 12896.99 Da        Isoelectric Point: 8.0166

>T49239 WP_042525901.1 NZ_CP009539:1435566-1435922 [Yersinia ruckeri]
MVKRKQGWDRGDIVLVDFNPVMGSEQRDARPALVLTKKLFNNLGIALVAPITQSGNYARHAGFTVSLSGAGCTTQGVVLL
NQVRMLDLMARNARFVEPLDEIAVNDALLKFATLVEID

Download         Length: 357 bp

>T49239 NZ_CP009539:1435566-1435922 [Yersinia ruckeri]
ATGGTGAAGCGTAAACAGGGATGGGATCGCGGCGATATCGTTTTAGTAGATTTTAACCCAGTAATGGGAAGTGAGCAGCG
AGATGCTCGTCCAGCGCTGGTATTGACAAAAAAACTGTTTAACAATCTCGGCATAGCCCTTGTTGCACCAATAACTCAGA
GCGGTAACTATGCACGCCATGCTGGTTTTACCGTGTCGCTGTCGGGTGCAGGATGTACAACGCAAGGTGTCGTTTTACTC
AATCAAGTCCGAATGCTCGATCTTATGGCACGAAATGCCCGCTTTGTGGAGCCGCTTGATGAAATCGCCGTAAATGACGC
TCTGCTGAAATTTGCGACTCTAGTCGAAATTGACTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9130.48 Da        Isoelectric Point: 5.6317

>AT49239 WP_042525899.1 NZ_CP009539:1435321-1435572 [Yersinia ruckeri]
MTIAIKKWGNSSGVVLPSLLLKKLGVTNGHHLDAEIKNGSLILTPTQRRYTLEELVAQCDKNAPMMAEEDVWGNDAPTGN
EIW

Download         Length: 252 bp

>AT49239 NZ_CP009539:1435321-1435572 [Yersinia ruckeri]
ATGACTATAGCAATCAAAAAGTGGGGCAACAGTAGTGGCGTTGTCTTACCCTCATTATTGTTGAAAAAACTAGGTGTTAC
CAACGGGCATCATCTTGATGCAGAAATCAAAAATGGCTCATTAATTCTTACTCCAACACAACGCCGCTATACGCTTGAAG
AGTTAGTCGCACAATGTGATAAAAATGCGCCAATGATGGCAGAAGAGGATGTTTGGGGTAACGACGCACCGACAGGGAAT
GAAATATGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References