Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1383490..1384159 Replicon chromosome
Accession NZ_CP009539
Organism Yersinia ruckeri strain YRB

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag BD65_RS06255 Protein ID WP_042525835.1
Coordinates 1383490..1383912 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag BD65_RS06260 Protein ID WP_004719196.1
Coordinates 1383893..1384159 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BD65_RS06235 1379329..1381062 - 1734 WP_042525829.1 single-stranded-DNA-specific exonuclease RecJ -
BD65_RS06240 1381069..1381785 - 717 WP_042525831.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
BD65_RS06245 1381817..1382716 - 900 WP_004719193.1 site-specific tyrosine recombinase XerD -
BD65_RS06250 1382824..1383342 + 519 WP_042525833.1 flavodoxin FldB -
BD65_RS06255 1383490..1383912 - 423 WP_042525835.1 protein YgfX Toxin
BD65_RS06260 1383893..1384159 - 267 WP_004719196.1 FAD assembly factor SdhE Antitoxin
BD65_RS06265 1384465..1385457 + 993 WP_042525836.1 tRNA-modifying protein YgfZ -
BD65_RS06270 1385596..1386237 - 642 WP_042528294.1 hemolysin III family protein -
BD65_RS16725 1386579..1386934 + 356 Protein_1230 HD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16639.55 Da        Isoelectric Point: 10.7607

>T49238 WP_042525835.1 NZ_CP009539:c1383912-1383490 [Yersinia ruckeri]
VAQWRCDLRVSWRTQLFSLLVHGVLVLLTLVVPWPDGFTPLWLILLTLVVFECIRSQKNITSRQGEIRLKAGNLLIWKWQ
EWTLVRPPWITRYGVLLSLQGTGRRRRKRIWLASDSMSEEEWRELCLILRHTFDSTADRE

Download         Length: 423 bp

>T49238 NZ_CP009539:c1383912-1383490 [Yersinia ruckeri]
GTGGCCCAGTGGCGATGTGATCTGCGGGTTTCATGGCGCACCCAACTTTTTTCACTATTGGTACACGGTGTTCTGGTATT
ACTGACACTGGTGGTGCCCTGGCCTGACGGATTTACTCCGCTATGGCTTATATTGCTGACGCTGGTGGTGTTTGAATGCA
TTCGCAGCCAGAAGAACATTACCTCTCGACAGGGAGAGATCCGGCTTAAAGCGGGAAATCTGTTGATTTGGAAGTGGCAA
GAGTGGACGTTGGTTCGGCCGCCGTGGATTACCCGCTACGGCGTATTATTATCGTTACAAGGTACTGGCCGCCGCCGCCG
AAAACGTATTTGGCTAGCCTCCGACAGCATGTCGGAAGAAGAATGGCGCGAGTTGTGTCTGATATTACGACATACTTTTG
ATTCTACAGCAGACCGTGAGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10532.09 Da        Isoelectric Point: 6.7185

>AT49238 WP_004719196.1 NZ_CP009539:c1384159-1383893 [Yersinia ruckeri]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDTLNDNDKRVFIRLLTSDDPDLFNWLMNHGEPQDSELKRMVKLIQTRN
KARGPVAM

Download         Length: 267 bp

>AT49238 NZ_CP009539:c1384159-1383893 [Yersinia ruckeri]
ATGGAAATTGATAACAAAGCCCGAATCCATTGGGCATGCCGCCGGGGTATGCGTGAACTGGATATCTCCATAATGCCATT
TTTCGAACATGAATATGACACGCTAAACGATAATGATAAGCGCGTATTTATCCGCTTGCTGACGAGTGATGATCCTGATT
TATTCAATTGGTTGATGAACCACGGCGAGCCGCAGGATAGCGAATTAAAACGAATGGTTAAACTGATTCAGACACGAAAT
AAAGCCCGTGGCCCAGTGGCGATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References