Detailed information of TA system TA049229

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 448460..449378
• Replicon: chromosome
• Accession: NZ_CP009539
• Organism: Yersinia ruckeri strain YRB

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: BD65_RS01960
• Protein ID: WP_042525001.1
• Coordinates: 448920..449378 (+)
• Length: 153 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: BD65_RS01955
• Protein ID: WP_042525000.1
• Coordinates: 448460..448906 (+)
• Length: 149 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BD65_RS01935	444158..444871	+	714	WP_042524997.1	murein tripeptide amidase MpaA	-
BD65_RS01940	444872..445846	-	975	WP_042524998.1	L-Ala-D/L-Glu epimerase	-
BD65_RS01945	445996..446499	+	504	WP_004717547.1	thiol peroxidase	-
BD65_RS01950	446534..448141	-	1608	WP_042524999.1	transcriptional regulator TyrR	-
BD65_RS01955	448460..448906	+	447	WP_042525000.1	DUF2384 domain-containing protein	Antitoxin
BD65_RS01960	448920..449378	+	459	WP_042525001.1	RES domain-containing protein	Toxin
BD65_RS01965	449382..450440	-	1059	WP_042525002.1	YcjF family protein	-
BD65_RS01970	450437..451834	-	1398	WP_042525003.1	YcjX family protein	-
BD65_RS01975	451815..452057	-	243	WP_144402957.1	phage shock protein PspD	-
BD65_RS01980	452120..452479	-	360	WP_004717559.1	envelope stress response membrane protein PspC	-
BD65_RS01985	452479..452706	-	228	WP_038242637.1	envelope stress response membrane protein PspB	-
BD65_RS01990	452790..453455	-	666	WP_042525004.1	phage shock protein PspA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-147)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (36-90)

Sequences

Toxin

Protein

• Length: 153 a.a.
• Molecular weight: 17030.47 Da
• Isoelectric Point: 6.6384

>T49229 WP_042525001.1 NZ_CP009539:448920-449378 [Yersinia ruckeri]
VMLYRIVHNRYLATAWSGYGAETYGGRWNHKGHAAIYLASSVSLAMLETLVHVEDSATLNDFNLFQITIPDNAIMVLQQQ
DWPRGWRDDPTPVATMDIGTEWIGSASSVGLLVPSTLVPLERNMLVNPKHRDFASCLKSINPLTFSFDPRLK

Nucleotide

• Length: 459 bp

>T49229 NZ_CP009539:448920-449378 [Yersinia ruckeri]
GTGATGCTCTACCGGATAGTTCACAACCGTTATCTGGCAACGGCCTGGAGCGGATATGGCGCAGAAACCTATGGTGGCCG
CTGGAATCATAAAGGTCATGCGGCGATTTATCTGGCCAGTAGCGTTTCTCTGGCGATGCTCGAAACACTGGTGCATGTAG
AAGACAGCGCGACGCTGAACGATTTTAATCTATTTCAGATAACCATTCCCGATAATGCAATTATGGTACTGCAACAGCAA
GATTGGCCACGTGGATGGCGAGATGACCCCACCCCCGTGGCCACCATGGACATCGGCACCGAATGGATTGGTTCAGCATC
ATCTGTCGGTCTGCTGGTACCATCCACGTTAGTCCCTTTGGAAAGAAATATGCTGGTGAATCCTAAACACCGCGACTTCG
CCTCGTGCCTGAAAAGCATCAATCCACTGACGTTCAGTTTTGATCCTCGTCTAAAGTAA

Antitoxin

Protein

• Length: 149 a.a.
• Molecular weight: 16404.84 Da
• Isoelectric Point: 8.0956

>AT49229 WP_042525000.1 NZ_CP009539:448460-448906 [Yersinia ruckeri]
MRTYHPSPMAKVSALWREIGLPASRGTALVDSIKLGFTVDVIDTIHLWADMPKSEILRATGIPSRSLTRRRTHDGRFTPE
ESERIARFVRVMDAAVDLFGGDRTKATVWMSTPVKGLGNRTPDSLLETETGALEICDLIGRLEHGVFS

Nucleotide

• Length: 447 bp

>AT49229 NZ_CP009539:448460-448906 [Yersinia ruckeri]
ATGAGAACTTATCACCCAAGCCCGATGGCCAAAGTCAGCGCACTATGGCGTGAGATTGGTCTACCCGCCAGTCGTGGCAC
CGCTTTGGTGGACAGCATAAAACTGGGATTTACTGTGGATGTGATCGACACTATACATTTATGGGCTGATATGCCTAAAT
CTGAAATATTACGCGCTACGGGCATTCCGAGCCGCAGTCTGACGCGCCGTCGTACCCATGATGGGCGTTTTACCCCGGAA
GAAAGCGAGCGTATTGCACGGTTTGTCCGGGTTATGGATGCGGCGGTAGATTTGTTCGGTGGTGACCGCACCAAAGCAAC
CGTGTGGATGTCGACGCCGGTCAAAGGACTGGGTAATCGAACGCCCGATTCACTGCTGGAAACCGAAACCGGTGCGTTGG
AAATCTGCGACCTGATTGGTCGTCTCGAACATGGGGTCTTTTCGTGA