49228

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 152541..153184 Replicon chromosome
Accession NZ_CP009539
Organism Yersinia ruckeri strain YRB

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag BD65_RS00650 Protein ID WP_042524811.1
Coordinates 152768..153184 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag BD65_RS00645 Protein ID WP_042524810.1
Coordinates 152541..152771 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BD65_RS00625 148732..149304 + 573 WP_042524807.1 HutD family protein -
BD65_RS00630 149354..150259 - 906 WP_042524808.1 LysR family transcriptional regulator -
BD65_RS00635 150391..151170 - 780 WP_042524809.1 Sua5/YciO/YrdC/YwlC family protein -
BD65_RS16220 151427..151726 - 300 Protein_129 HoxN/HupN/NixA family nickel/cobalt transporter -
BD65_RS00645 152541..152771 + 231 WP_042524810.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
BD65_RS00650 152768..153184 + 417 WP_042524811.1 type II toxin-antitoxin system VapC family toxin Toxin
BD65_RS00655 153230..153763 - 534 Protein_132 pcar -
BD65_RS17020 153952..154089 + 138 WP_158499435.1 hypothetical protein -
BD65_RS00660 154227..155318 - 1092 WP_004721156.1 redox-regulated ATPase YchF -
BD65_RS00665 155605..156042 + 438 WP_042524813.1 hypothetical protein -
BD65_RS00670 156104..156694 - 591 WP_042524814.1 aminoacyl-tRNA hydrolase -
BD65_RS00675 156999..157271 + 273 WP_042524815.1 stress-induced protein YchH -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-129)

Antitoxin

SpoVT-AbrB domain

(7-50)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15139.62 Da        Isoelectric Point: 7.8874

>T49228 WP_042524811.1 NZ_CP009539:152768-153184 [Yersinia ruckeri]
VNKTYMLDTNICSFIMREQPEAVIRRLEQAVLRNHRIVVSAITYAEMRFGAIGKKASPRHALLVDAFCARLDAILPWDRA
AVDATTEVKAALTAVGTPIGPNDTAIAGHAIAAGVILVTNNMREFERVPSLVLEDWVK

Download         Length: 417 bp

>T49228 NZ_CP009539:152768-153184 [Yersinia ruckeri]
GTGAACAAAACGTATATGCTGGACACCAATATCTGCTCATTCATCATGCGTGAGCAGCCGGAAGCGGTGATCAGACGTCT
GGAGCAAGCGGTGCTGCGCAATCATCGCATCGTGGTCTCGGCCATTACCTACGCCGAGATGCGCTTCGGTGCCATCGGAA
AAAAGGCCTCACCGCGCCACGCATTGCTGGTCGATGCGTTCTGCGCCCGCCTTGATGCCATCCTGCCGTGGGATCGTGCT
GCGGTAGATGCCACCACAGAGGTCAAAGCTGCACTTACTGCAGTAGGTACACCGATCGGCCCCAACGACACGGCAATTGC
CGGACATGCCATTGCTGCAGGAGTCATTCTGGTGACCAATAACATGAGAGAGTTTGAGCGGGTGCCGAGCCTGGTGCTGG
AAGACTGGGTGAAGTAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8638.74 Da        Isoelectric Point: 4.6017

>AT49228 WP_042524810.1 NZ_CP009539:152541-152771 [Yersinia ruckeri]
MRTVSIFKNGNNRAIRLPRDLDFEGVSELEIVREGDSIILRPVRPTWGSFAQLEKADADFMAEREGVVSDEGRFNL

Download         Length: 231 bp

>AT49228 NZ_CP009539:152541-152771 [Yersinia ruckeri]
ATGCGAACGGTATCTATTTTCAAAAACGGTAATAACCGCGCCATCCGTCTGCCCCGCGATCTGGATTTTGAGGGAGTGAG
CGAGCTGGAGATCGTCCGCGAAGGGGACAGCATCATTCTGCGTCCCGTCAGGCCGACCTGGGGCTCGTTCGCGCAGCTGG
AAAAGGCCGACGCAGATTTTATGGCGGAGCGTGAGGGCGTTGTCAGCGACGAAGGACGATTTAACCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References