49210

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-PumB/upstrm_HI1419-dnstrm_HI1420
Location 1197634..1198259 Replicon chromosome
Accession NZ_CP009533
Organism Pseudomonas rhizosphaerae strain DSM 16299

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LT40_RS05460 Protein ID WP_148308601.1
Coordinates 1197954..1198259 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag LT40_RS05455 Protein ID WP_052393255.1
Coordinates 1197634..1197957 (-) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LT40_RS05435 1193021..1194850 - 1830 WP_043193325.1 ABC transporter ATP-binding protein/permease -
LT40_RS05440 1194917..1195480 - 564 WP_043187354.1 peptidylprolyl isomerase -
LT40_RS05445 1195630..1196577 - 948 WP_043187357.1 LysR family transcriptional regulator -
LT40_RS05450 1196778..1197644 + 867 WP_043187359.1 carboxylate/amino acid/amine transporter -
LT40_RS05455 1197634..1197957 - 324 WP_052393255.1 putative addiction module antidote protein Antitoxin
LT40_RS05460 1197954..1198259 - 306 WP_148308601.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LT40_RS05465 1198561..1199748 + 1188 WP_084139717.1 sugar transporter -
LT40_RS05470 1199908..1200420 + 513 WP_043193327.1 sigma-70 family RNA polymerase sigma factor -
LT40_RS05475 1200414..1201364 + 951 WP_043187367.1 FecR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-95)

Antitoxin

Cro/C1-type helix-turn-helix domain

(39-91)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11886.54 Da        Isoelectric Point: 7.2446

>T49210 WP_148308601.1 NZ_CP009533:c1198259-1197954 [Pseudomonas rhizosphaerae]
MMKIATTDVFERWFTRLRDRQAAIRIQARIDRLEDGNWGDWQSVGEGVCEMRLHFGPGYRLYFMQHEQCWIVLLAGGDKS
TQSSDIAIAKRMAHQLQEQER

Download         Length: 306 bp

>T49210 NZ_CP009533:c1198259-1197954 [Pseudomonas rhizosphaerae]
CTGATGAAGATCGCCACAACGGATGTGTTTGAGCGCTGGTTCACTCGATTGCGCGATCGCCAGGCCGCCATACGGATCCA
GGCCCGGATCGACAGGCTGGAAGACGGGAACTGGGGTGACTGGCAGTCAGTGGGAGAAGGCGTATGCGAGATGCGGCTTC
ATTTTGGGCCAGGCTACCGCCTGTACTTCATGCAACACGAGCAGTGCTGGATAGTGCTGTTGGCTGGTGGCGACAAGTCG
ACACAGTCCTCCGACATCGCTATCGCCAAGCGCATGGCACACCAACTTCAGGAACAGGAACGATGA

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11346.08 Da        Isoelectric Point: 7.1650

>AT49210 WP_052393255.1 NZ_CP009533:c1197957-1197634 [Pseudomonas rhizosphaerae]
MKIKLREWDSAEHLKTDQDMIMYFDACMAEAGDDAAFIAKALGNIARAKGIAQVAKDTGLGRESLYKALSEDGNPSFATI
LKVTRALGISLHAGLLASPSRPAPAIG

Download         Length: 324 bp

>AT49210 NZ_CP009533:c1197957-1197634 [Pseudomonas rhizosphaerae]
ATGAAAATCAAGCTACGGGAATGGGACAGCGCTGAACACCTCAAAACCGATCAGGACATGATCATGTACTTCGATGCTTG
CATGGCCGAAGCTGGTGATGACGCGGCATTCATTGCCAAGGCGCTGGGCAACATTGCGCGCGCCAAGGGTATAGCCCAGG
TGGCGAAGGACACCGGGCTGGGTCGCGAGAGTTTGTACAAAGCGCTTTCGGAAGACGGCAATCCGAGCTTCGCGACGATA
CTGAAGGTGACGCGTGCACTGGGTATCTCTCTGCATGCAGGCCTGCTTGCATCACCCTCTCGCCCTGCCCCTGCTATCGG
CTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References