Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DhiAT/dnstrm_HI1420(antitoxin)
Location 1052142..1052898 Replicon chromosome
Accession NZ_CP009460
Organism Dickeya fangzhongdai strain ND14b

Toxin (Protein)


Gene name dhiT Uniprot ID -
Locus tag LH89_RS04550 Protein ID WP_038660239.1
Coordinates 1052641..1052898 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name dhiA Uniprot ID -
Locus tag LH89_RS04545 Protein ID WP_038660236.1
Coordinates 1052142..1052630 (-) Length 163 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LH89_RS04520 1048080..1049807 + 1728 WP_038660219.1 hydrogenase large subunit -
LH89_RS04525 1049818..1050387 + 570 WP_038660223.1 hydrogenase 4 subunit H -
LH89_RS04530 1050384..1051175 + 792 WP_038660225.1 NADH-quinone oxidoreductase subunit B family protein -
LH89_RS04535 1051172..1051570 + 399 WP_038660229.1 formate hydrogenlyase maturation HycH family protein -
LH89_RS04540 1051563..1052060 + 498 WP_038660233.1 hydrogenase maturation peptidase HycI -
LH89_RS04545 1052142..1052630 - 489 WP_038660236.1 DUF2442 domain-containing protein Antitoxin
LH89_RS04550 1052641..1052898 - 258 WP_038660239.1 DUF4160 domain-containing protein Toxin
LH89_RS04555 1053396..1053938 + 543 WP_013317225.1 4Fe-4S dicluster domain-containing protein -
LH89_RS04560 1053973..1056123 + 2151 WP_038660243.1 formate dehydrogenase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Protein of unknown function DUF4160

(9-74)

Antitoxin

Uncharacterized protein HI1420

(79-157)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9994.57 Da        Isoelectric Point: 8.9627

>T49107 WP_038660239.1 NZ_CP009460:c1052898-1052641 [Dickeya fangzhongdai]
MPEIDRLAGLIFHLYFYDNERHHLPHVHVCYGNHELIISIRTGTEIEGYLPNNKRKMALAHIRAHREQLLSMWERAVVGR
NPGKL

Download         Length: 258 bp

>T49107 NZ_CP009460:c1052898-1052641 [Dickeya fangzhongdai]
ATGCCTGAGATTGACAGACTGGCAGGGCTAATTTTCCATTTGTACTTTTACGATAATGAACGGCACCACTTGCCGCATGT
ACATGTCTGTTATGGCAACCATGAGCTGATCATCAGTATTCGTACTGGAACAGAGATCGAAGGATATCTGCCGAATAACA
AGCGCAAGATGGCGCTTGCGCATATCAGAGCTCATCGGGAACAACTGCTGAGTATGTGGGAGCGGGCGGTTGTGGGGAGA
AATCCGGGAAAATTGTGA

Antitoxin


Download         Length: 163 a.a.        Molecular weight: 17940.47 Da        Isoelectric Point: 6.6439

>AT49107 WP_038660236.1 NZ_CP009460:c1052630-1052142 [Dickeya fangzhongdai]
MHKIVEVDVIGDFSLRLTYEDGLVCDINLYQYASSPVFSNTSLFIKFGLLPDGALEWSPDIKISASELRKKGEYVSHTLA
VRENNFADVISRAFYDAVIENRPEILQAALKIAVEKHGNSTVAKEAGAKSRTSLYKSLNKNTHVSLATVVSLAHTVLQLE
EK

Download         Length: 489 bp

>AT49107 NZ_CP009460:c1052630-1052142 [Dickeya fangzhongdai]
ATGCATAAAATCGTGGAAGTTGACGTGATTGGCGACTTTTCGTTGCGCCTGACCTATGAAGATGGTTTGGTTTGCGACAT
CAATCTTTATCAATATGCCTCCAGCCCGGTATTTTCGAACACCAGCCTATTTATCAAGTTTGGGCTGCTGCCGGATGGCG
CGCTGGAATGGTCGCCGGATATTAAGATTTCCGCGTCGGAATTGCGGAAAAAAGGGGAGTATGTCAGCCACACGCTTGCG
GTGCGAGAAAACAACTTCGCTGATGTCATCTCTCGCGCCTTCTATGATGCCGTGATTGAAAACCGGCCGGAAATTCTGCA
AGCGGCGTTGAAAATCGCGGTGGAAAAACATGGCAACAGCACCGTAGCCAAAGAGGCGGGGGCGAAAAGTCGCACCAGCC
TATATAAGTCGCTGAATAAAAATACCCATGTCAGCCTGGCGACGGTGGTCAGCCTGGCGCATACCGTGCTGCAACTGGAA
GAGAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References