Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Doc-RelB
Location 51272..51867 Replicon chromosome
Accession NZ_CP009460
Organism Dickeya fangzhongdai strain ND14b

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag LH89_RS00240 Protein ID WP_038658062.1
Coordinates 51490..51867 (+) Length 126 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag LH89_RS00235 Protein ID WP_038658060.1
Coordinates 51272..51493 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LH89_RS00215 47676..48395 + 720 WP_038658054.1 nitrate reductase molybdenum cofactor assembly chaperone -
LH89_RS00220 48395..49072 + 678 WP_038658056.1 respiratory nitrate reductase subunit gamma -
LH89_RS21815 49145..49705 - 561 WP_049869904.1 NUDIX domain-containing protein -
LH89_RS00230 49987..51135 + 1149 WP_038658058.1 L-threonine dehydrogenase -
LH89_RS00235 51272..51493 + 222 WP_038658060.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LH89_RS00240 51490..51867 + 378 WP_038658062.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
LH89_RS00245 52012..52830 + 819 WP_038658064.1 abortive infection family protein -
LH89_RS00250 53182..53805 + 624 WP_038658067.1 glutathione S-transferase family protein -
LH89_RS00255 54063..55094 - 1032 WP_038658069.1 methionine synthase -
LH89_RS00260 55122..56099 - 978 WP_038658071.1 DUF1852 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(4-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-52)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 14194.26 Da        Isoelectric Point: 5.1873

>T49097 WP_038658062.1 NZ_CP009460:51490-51867 [Dickeya fangzhongdai]
MKWVSAQDVIAFHDRILQVLPGVAGMADPGRAEALIYRVQNRLYYEDMTDLFELAATYWVTVARGHIFNDGNKRTAFFVT
MVFLRRNGVLIADNDNSLEELTVKAATGECQVSELAEQLRLRVEK

Download         Length: 378 bp

>T49097 NZ_CP009460:51490-51867 [Dickeya fangzhongdai]
ATGAAATGGGTCAGTGCGCAGGACGTTATCGCCTTTCATGATCGCATCCTGCAGGTGTTGCCAGGAGTTGCTGGTATGGC
GGATCCTGGCCGGGCTGAAGCCTTGATTTATCGGGTGCAGAACCGGCTTTATTATGAAGATATGACGGATCTCTTTGAAC
TGGCAGCGACGTATTGGGTAACTGTTGCGCGGGGTCATATTTTTAATGATGGTAATAAGCGCACCGCCTTTTTCGTCACC
ATGGTATTTTTACGCCGCAATGGTGTATTAATTGCCGATAACGATAATTCACTGGAAGAGCTTACCGTCAAGGCAGCAAC
GGGTGAATGCCAGGTGTCGGAACTCGCGGAGCAGTTAAGACTGCGGGTGGAAAAGTAA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8218.32 Da        Isoelectric Point: 7.2021

>AT49097 WP_038658060.1 NZ_CP009460:51272-51493 [Dickeya fangzhongdai]
MKTYTITEVRQNIAAVIDTAARGEPVEITRRNGTSAVLIPKAEFEAYQNARLDAEFDFIMQRHGHTVKALADR

Download         Length: 222 bp

>AT49097 NZ_CP009460:51272-51493 [Dickeya fangzhongdai]
ATGAAAACGTACACCATTACTGAAGTCCGGCAAAACATTGCGGCGGTCATCGATACGGCGGCCCGCGGCGAGCCGGTGGA
AATTACGCGTCGAAATGGTACGTCGGCCGTACTCATCCCCAAGGCGGAATTTGAGGCGTATCAGAACGCCAGACTAGACG
CTGAATTTGATTTCATCATGCAGCGCCACGGCCACACGGTTAAAGCGCTTGCCGACAGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References