Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 1623901..1624496 Replicon chromosome
Accession NZ_CP009459
Organism Cedecea neteri strain ND14a

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag LH86_RS07660 Protein ID WP_039299861.1
Coordinates 1624146..1624496 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag LH86_RS07655 Protein ID WP_039299859.1
Coordinates 1623901..1624152 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LH86_RS07645 1619557..1623333 + 3777 WP_039299856.1 translocation/assembly module TamB -
LH86_RS07650 1623336..1623680 + 345 WP_008460443.1 gamma-glutamylcyclotransferase -
LH86_RS07655 1623901..1624152 + 252 WP_039299859.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
LH86_RS07660 1624146..1624496 + 351 WP_039299861.1 type II toxin-antitoxin system ChpB family toxin Toxin
LH86_RS07665 1624545..1625075 - 531 WP_008460444.1 inorganic diphosphatase -
LH86_RS07670 1625359..1626912 + 1554 WP_039299864.1 Tar ligand binding domain-containing protein -
LH86_RS07675 1627050..1627547 + 498 WP_039299867.1 DUF2569 domain-containing protein -
LH86_RS07680 1627593..1628591 - 999 WP_008460446.1 class 1 fructose-bisphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

Antitoxin PemI-like

(1-83)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12278.00 Da        Isoelectric Point: 4.8003

>T49086 WP_039299861.1 NZ_CP009459:1624146-1624496 [Cedecea neteri]
MVRRGGFERGDIVLVGFNPAVGREQQGEGRPALVLSTRAFNQTGTALVAPITQGGNYARDAGFAVSLSGCGTETCGVVLI
NQARMVDLECRGAQKLETVPADIVEEVLARFQAILE

Download         Length: 351 bp

>T49086 NZ_CP009459:1624146-1624496 [Cedecea neteri]
TTGGTGAGACGCGGGGGTTTTGAAAGGGGAGATATTGTTCTCGTGGGGTTCAATCCCGCCGTTGGCCGGGAGCAACAGGG
AGAAGGCCGTCCTGCTCTTGTGCTTTCAACCCGGGCATTTAACCAGACGGGCACTGCGCTAGTGGCACCTATAACCCAGG
GCGGAAATTATGCAAGGGACGCAGGTTTTGCCGTTTCACTTAGCGGATGCGGGACAGAGACCTGTGGCGTGGTGTTAATT
AATCAAGCCAGAATGGTCGATCTTGAATGCCGTGGAGCACAGAAACTTGAAACCGTTCCGGCAGACATTGTCGAGGAAGT
TTTGGCACGTTTTCAGGCCATCCTCGAATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9208.74 Da        Isoelectric Point: 5.0807

>AT49086 WP_039299859.1 NZ_CP009459:1623901-1624152 [Cedecea neteri]
MRITIKKWGNSAGMVIPGALMDELGVKIGQSLEAEVMNNQLIMKPIRKKYTLDELLAQGDPSAPKVSEEDIWGKDNPVGK
EVW

Download         Length: 252 bp

>AT49086 NZ_CP009459:1623901-1624152 [Cedecea neteri]
ATGCGCATTACCATCAAAAAATGGGGGAACAGTGCTGGTATGGTCATTCCCGGAGCACTAATGGATGAACTAGGCGTAAA
AATTGGACAAAGCCTGGAGGCTGAAGTGATGAATAATCAACTGATCATGAAACCCATAAGGAAGAAATACACGCTGGACG
AACTGTTGGCTCAGGGCGACCCGTCGGCACCAAAAGTTTCTGAAGAAGACATTTGGGGCAAGGATAACCCGGTCGGGAAA
GAAGTTTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References