Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 996734..997236 Replicon chromosome
Accession NZ_CP009459
Organism Cedecea neteri strain ND14a

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LH86_RS04725 Protein ID WP_039298829.1
Coordinates 996982..997236 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LH86_RS04720 Protein ID WP_039298826.1
Coordinates 996734..996985 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LH86_RS04695 991948..992682 - 735 WP_039298815.1 cellulose synthase operon protein YhjQ -
LH86_RS04700 992695..992880 - 186 WP_038483072.1 YhjR family protein -
LH86_RS04705 993054..994616 + 1563 WP_039298818.1 cellulose biosynthesis protein BcsE -
LH86_RS04710 994613..994807 + 195 WP_008460596.1 cellulose biosynthesis protein BcsF -
LH86_RS04715 994800..996482 + 1683 WP_039298822.1 cellulose biosynthesis protein BcsG -
LH86_RS04720 996734..996985 + 252 WP_039298826.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
LH86_RS04725 996982..997236 + 255 WP_039298829.1 Txe/YoeB family addiction module toxin Toxin
LH86_RS04730 997288..997950 - 663 WP_039298832.1 OmpA family lipoprotein -
LH86_RS04735 998105..1000435 + 2331 WP_039298836.1 molybdopterin guanine dinucleotide-containing S/N-oxide reductase -
LH86_RS04740 1000383..1000844 - 462 WP_039298839.1 N-acetyltransferase -
LH86_RS04745 1000841..1001404 - 564 WP_039298842.1 DNA-3-methyladenine glycosylase I -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10549.27 Da        Isoelectric Point: 9.6573

>T49085 WP_039298829.1 NZ_CP009459:996982-997236 [Cedecea neteri]
MMLCWHHQAWEDYLYFQRTDKKMVKRINDLIKEIRRTPFQGIGKPEPLKFNWSGYWSRRIDEEHRLVYTTKDEKIIIVVC
RYHY

Download         Length: 255 bp

>T49085 NZ_CP009459:996982-997236 [Cedecea neteri]
ATGATGCTTTGCTGGCACCATCAGGCCTGGGAAGACTACCTTTATTTCCAGCGCACGGATAAAAAGATGGTGAAACGTAT
CAACGACCTGATTAAAGAAATCCGTCGAACGCCGTTTCAGGGCATAGGCAAGCCAGAGCCACTCAAGTTCAACTGGTCAG
GATACTGGTCACGACGCATAGATGAAGAACATCGTCTGGTTTATACGACGAAGGACGAGAAAATTATTATCGTCGTCTGC
CGCTATCACTATTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9541.62 Da        Isoelectric Point: 4.3313

>AT49085 WP_039298826.1 NZ_CP009459:996734-996985 [Cedecea neteri]
MRTITYSKARQELADTMQKVIDDRDPILITRQNGGNCVLLSEEHYNSLEETAYLLRSPANAARLSQAIEDINNDLYNERD
IIE

Download         Length: 252 bp

>AT49085 NZ_CP009459:996734-996985 [Cedecea neteri]
ATGCGCACCATTACATACAGTAAAGCACGGCAGGAGCTGGCAGATACCATGCAAAAGGTCATTGACGATCGGGACCCAAT
TTTGATTACCCGGCAAAACGGAGGCAACTGCGTGCTGCTGAGTGAAGAGCATTACAACTCACTGGAAGAAACAGCCTATC
TTTTACGCTCTCCGGCAAATGCGGCCAGACTGAGTCAGGCAATCGAAGACATCAATAACGATCTCTACAACGAAAGAGAC
ATTATTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References