Detailed information of TA system TA049043

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): shpAB/BrnT-BrnA
• Location: 379532..380114
• Replicon: chromosome
• Accession: NZ_CP009454
• Organism: Pantoea rwandensis strain ND04

Toxin (Protein)

• Gene name: shpA
• Uniprot ID: -
• Locus tag: LH22_RS01650
• Protein ID: WP_038643836.1
• Coordinates: 379815..380114 (-)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: shpB
• Uniprot ID: -
• Locus tag: LH22_RS01645
• Protein ID: WP_038643835.1
• Coordinates: 379532..379834 (-)
• Length: 101 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LH22_RS01640	375958..379431	+	3474	WP_038643834.1	cellulose biosynthesis protein BcsC	-
LH22_RS01645	379532..379834	-	303	WP_038643835.1	BrnA antitoxin family protein	Antitoxin
LH22_RS01650	379815..380114	-	300	WP_038643836.1	BrnT family toxin	Toxin
LH22_RS01655	380331..381335	-	1005	WP_038643837.1	endoglucanase	-
LH22_RS01660	381345..381791	-	447	WP_038643838.1	cellulose synthase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (9-90)

Antitoxin

• BrnA antitoxin of type II toxin-antitoxin system (10-93)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11616.91 Da
• Isoelectric Point: 6.2311

>T49043 WP_038643836.1 NZ_CP009454:c380114-379815 [Pantoea rwandensis]
MQTELEFEWDTIKAETNIRKHGISFEIAARVFDDPYHIASQDRVENGEYRWQTLGSVSGYLIVLVAHTVRFEQGTEIVRI
ISARSATRNERRRYEQNQS

Nucleotide

• Length: 300 bp

>T49043 NZ_CP009454:c380114-379815 [Pantoea rwandensis]
ATGCAAACGGAATTGGAGTTTGAATGGGATACCATCAAAGCGGAAACCAACATCCGCAAGCATGGCATCAGCTTTGAAAT
TGCAGCCAGAGTCTTTGATGACCCTTATCACATCGCTAGTCAGGATCGCGTTGAAAACGGCGAATATCGCTGGCAGACGT
TGGGTAGTGTGTCGGGTTATCTCATCGTATTGGTTGCCCATACGGTCAGATTTGAACAGGGTACCGAGATTGTCAGGATC
ATCAGTGCTCGTTCTGCAACGCGAAATGAGAGGAGGCGATATGAGCAAAATCAGAGTTAA

Antitoxin

Protein

• Length: 101 a.a.
• Molecular weight: 11407.09 Da
• Isoelectric Point: 9.6212

>AT49043 WP_038643835.1 NZ_CP009454:c379834-379532 [Pantoea rwandensis]
MSKIRVKRSELPPLTDKQQLELEALSQKADGDIDFEDIAPLDDAFWSTATRGRFYRPVKTQASVRIDADVLEWLKAPGKG
YQTRLNAILRAAMMRELQSK

Nucleotide

• Length: 303 bp

>AT49043 NZ_CP009454:c379834-379532 [Pantoea rwandensis]
ATGAGCAAAATCAGAGTTAAACGCAGTGAACTGCCGCCGCTTACAGATAAACAGCAGTTGGAACTGGAAGCGTTGAGTCA
AAAAGCGGACGGAGACATTGATTTTGAGGACATTGCGCCGTTAGACGACGCCTTCTGGAGCACAGCTACGCGCGGCCGCT
TCTATCGTCCGGTAAAAACGCAAGCCTCGGTGAGGATTGATGCCGATGTTCTGGAATGGCTGAAAGCGCCAGGGAAAGGT
TACCAGACGCGCTTGAATGCGATTTTGCGCGCCGCCATGATGCGAGAGCTGCAAAGCAAATAG