Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3404779..3405448 Replicon chromosome
Accession NZ_CP009451
Organism Cedecea neteri strain SSMD04

Toxin (Protein)


Gene name cptA Uniprot ID A0A089Q6L3
Locus tag JT31_RS15810 Protein ID WP_038479154.1
Coordinates 3405026..3405448 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A089Q1B2
Locus tag JT31_RS15805 Protein ID WP_038479151.1
Coordinates 3404779..3405045 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JT31_RS15785 3401295..3402023 - 729 WP_038479136.1 MurR/RpiR family transcriptional regulator -
JT31_RS15790 3402066..3402659 - 594 WP_038479142.1 HD domain-containing protein -
JT31_RS15795 3402838..3403491 + 654 WP_038479145.1 hemolysin III family protein -
JT31_RS15800 3403546..3404532 - 987 WP_038479148.1 tRNA-modifying protein YgfZ -
JT31_RS15805 3404779..3405045 + 267 WP_038479151.1 FAD assembly factor SdhE Antitoxin
JT31_RS15810 3405026..3405448 + 423 WP_038479154.1 membrane protein Toxin
JT31_RS15815 3405445..3405966 - 522 WP_038479157.1 flavodoxin FldB -
JT31_RS15820 3406069..3406965 + 897 WP_038479160.1 site-specific tyrosine recombinase XerD -
JT31_RS15825 3406992..3407708 + 717 WP_038479165.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
JT31_RS15830 3407715..3409448 + 1734 WP_038479170.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16485.40 Da        Isoelectric Point: 11.7122

>T49024 WP_038479154.1 NZ_CP009451:3405026-3405448 [Cedecea neteri]
VVLWQSDLRVSWRAQWLSLLLHGLVALLVLLTPWPMSYTLVWMLLLSLVVFDSVRSQRRIHARQGEIKLLTDFRLRWQGR
DWDIVGNPWMIDSGAMLRLRRPGKQRCQHLWLAADSMDIGEWRDLRRLLMQQQASGSGQI

Download         Length: 423 bp

>T49024 NZ_CP009451:3405026-3405448 [Cedecea neteri]
GTGGTCCTGTGGCAATCTGATCTCCGGGTTTCCTGGCGCGCGCAGTGGCTTTCATTGCTTCTCCACGGTCTGGTGGCACT
GCTTGTGCTGCTCACGCCGTGGCCGATGAGCTATACGCTCGTCTGGATGCTGCTGCTTTCCCTGGTGGTTTTCGACAGCG
TGCGTAGCCAGCGCCGCATTCACGCACGTCAGGGCGAAATCAAGCTGCTGACGGACTTTCGCCTGCGCTGGCAGGGGCGT
GACTGGGACATCGTCGGGAATCCGTGGATGATTGACAGCGGTGCGATGCTAAGACTGCGTCGGCCCGGTAAACAGCGTTG
CCAGCATCTTTGGCTGGCCGCTGACAGCATGGACATCGGCGAATGGCGTGATTTACGTCGCCTGCTGATGCAACAACAGG
CGAGCGGAAGCGGGCAGATTTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10431.91 Da        Isoelectric Point: 5.6202

>AT49024 WP_038479151.1 NZ_CP009451:3404779-3405045 [Cedecea neteri]
MDINNKARIHWACRRGMRELDISIMPFFEHEYETLSDSDKQLFVRLLESDDPDLFNWLMNHGKPADTELQRMVSLIQTRN
KERGPVAI

Download         Length: 267 bp

>AT49024 NZ_CP009451:3404779-3405045 [Cedecea neteri]
ATGGATATCAATAATAAAGCCCGAATTCACTGGGCATGCCGCCGTGGAATGCGCGAGCTCGATATTTCGATTATGCCGTT
CTTCGAACATGAATATGAAACGCTTAGCGACAGCGACAAGCAGCTGTTTGTCCGCCTGCTGGAGTCTGACGATCCTGACC
TGTTTAACTGGTTGATGAACCACGGTAAACCTGCGGATACGGAACTTCAGCGTATGGTTAGCCTGATTCAGACACGGAAT
AAAGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A089Q6L3

Antitoxin

Source ID Structure
AlphaFold DB A0A089Q1B2

References