Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | mazF-pemI/MazF(toxin) |
Location | 729184..729820 | Replicon | chromosome |
Accession | NZ_CP009416 | ||
Organism | Jeotgalibacillus malaysiensis strain malaysiensis |
Toxin (Protein)
Gene name | mazF | Uniprot ID | - |
Locus tag | JMA_RS04110 | Protein ID | WP_039807348.1 |
Coordinates | 729470..729820 (+) | Length | 117 a.a. |
Antitoxin (Protein)
Gene name | pemI | Uniprot ID | A0A0B5AJA0 |
Locus tag | JMA_RS04105 | Protein ID | WP_039807347.1 |
Coordinates | 729184..729465 (+) | Length | 94 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
JMA_RS04085 | 725331..725927 | - | 597 | WP_039807344.1 | rhomboid family intramembrane serine protease | - |
JMA_RS04090 | 725993..726349 | + | 357 | WP_039813227.1 | holo-ACP synthase | - |
JMA_RS04095 | 726818..727831 | + | 1014 | Protein_786 | outer membrane lipoprotein carrier protein LolA | - |
JMA_RS04100 | 727881..729029 | + | 1149 | WP_173425103.1 | alanine racemase | - |
JMA_RS04105 | 729184..729465 | + | 282 | WP_039807347.1 | hypothetical protein | Antitoxin |
JMA_RS04110 | 729470..729820 | + | 351 | WP_039807348.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin |
JMA_RS04115 | 729935..730762 | + | 828 | WP_039807350.1 | STAS domain-containing protein | - |
JMA_RS04120 | 730766..731122 | + | 357 | WP_039807352.1 | STAS domain-containing protein | - |
JMA_RS04125 | 731127..731528 | + | 402 | WP_039807354.1 | anti-sigma regulatory factor | - |
JMA_RS04130 | 731545..732555 | + | 1011 | WP_039807356.1 | PP2C family protein-serine/threonine phosphatase | - |
JMA_RS04135 | 732678..733013 | + | 336 | WP_039807358.1 | anti-sigma factor antagonist | - |
JMA_RS04140 | 733010..733483 | + | 474 | WP_039807360.1 | anti-sigma B factor RsbW | - |
JMA_RS04145 | 733461..734255 | + | 795 | WP_039807362.1 | RNA polymerase sigma factor SigB | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 12850.82 Da Isoelectric Point: 5.1663
>T48847 WP_039807348.1 NZ_CP009416:729470-729820 [Jeotgalibacillus malaysiensis]
MIVKRGDVFFADLSPVVGSEQGGVRPVLIIQNDIGNRFSPTVVVAAITAQIQKAKLPTHVEISSKRNGFERDSVILLEQI
RTLDKQRLTDKITHLDDETMEKVDEALQISLGLVDL
MIVKRGDVFFADLSPVVGSEQGGVRPVLIIQNDIGNRFSPTVVVAAITAQIQKAKLPTHVEISSKRNGFERDSVILLEQI
RTLDKQRLTDKITHLDDETMEKVDEALQISLGLVDL
Download Length: 351 bp
>T48847 NZ_CP009416:729470-729820 [Jeotgalibacillus malaysiensis]
TTGATAGTGAAGCGTGGAGACGTATTTTTTGCTGACCTATCTCCCGTTGTCGGTTCAGAGCAAGGTGGAGTCCGCCCCGT
TCTCATCATCCAAAACGACATCGGAAATCGGTTTAGTCCCACAGTAGTGGTCGCAGCAATTACAGCACAAATTCAAAAAG
CTAAGCTTCCTACCCACGTTGAAATCAGCTCAAAGCGTAATGGCTTTGAACGTGATTCAGTTATTTTGCTGGAACAGATC
AGAACTTTAGACAAACAACGATTAACAGACAAAATAACCCATCTGGATGACGAGACGATGGAAAAGGTAGACGAGGCGCT
TCAGATCAGCCTCGGCTTGGTAGACCTCTAA
TTGATAGTGAAGCGTGGAGACGTATTTTTTGCTGACCTATCTCCCGTTGTCGGTTCAGAGCAAGGTGGAGTCCGCCCCGT
TCTCATCATCCAAAACGACATCGGAAATCGGTTTAGTCCCACAGTAGTGGTCGCAGCAATTACAGCACAAATTCAAAAAG
CTAAGCTTCCTACCCACGTTGAAATCAGCTCAAAGCGTAATGGCTTTGAACGTGATTCAGTTATTTTGCTGGAACAGATC
AGAACTTTAGACAAACAACGATTAACAGACAAAATAACCCATCTGGATGACGAGACGATGGAAAAGGTAGACGAGGCGCT
TCAGATCAGCCTCGGCTTGGTAGACCTCTAA
Antitoxin
Download Length: 94 a.a. Molecular weight: 10575.94 Da Isoelectric Point: 4.9061
>AT48847 WP_039807347.1 NZ_CP009416:729184-729465 [Jeotgalibacillus malaysiensis]
VSESSATSEILVRLPKQLLTELEAFAEQEELSCSDCIYRATKAYVRDRRRKQTQDAMRRGYMEMAKINLSMASEALQAEY
EADHTIERLVSGG
VSESSATSEILVRLPKQLLTELEAFAEQEELSCSDCIYRATKAYVRDRRRKQTQDAMRRGYMEMAKINLSMASEALQAEY
EADHTIERLVSGG
Download Length: 282 bp
>AT48847 NZ_CP009416:729184-729465 [Jeotgalibacillus malaysiensis]
GTGTCGGAATCCAGCGCAACATCAGAAATCTTGGTACGATTACCAAAGCAACTGCTTACAGAACTGGAAGCGTTTGCCGA
ACAGGAAGAGTTAAGCTGCAGTGATTGCATTTACCGTGCAACGAAAGCTTATGTCCGTGACAGACGCCGGAAACAAACTC
AAGATGCGATGCGCCGGGGCTATATGGAAATGGCGAAGATCAACTTGTCAATGGCTTCGGAAGCACTTCAGGCAGAGTAC
GAAGCAGACCATACCATTGAACGATTGGTAAGTGGAGGATAA
GTGTCGGAATCCAGCGCAACATCAGAAATCTTGGTACGATTACCAAAGCAACTGCTTACAGAACTGGAAGCGTTTGCCGA
ACAGGAAGAGTTAAGCTGCAGTGATTGCATTTACCGTGCAACGAAAGCTTATGTCCGTGACAGACGCCGGAAACAAACTC
AAGATGCGATGCGCCGGGGCTATATGGAAATGGCGAAGATCAACTTGTCAATGGCTTCGGAAGCACTTCAGGCAGAGTAC
GAAGCAGACCATACCATTGAACGATTGGTAAGTGGAGGATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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