48825

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 3991152..3991671 Replicon chromosome
Accession NZ_CP009365
Organism Pseudomonas soli strain SJ10

Toxin (Protein)


Gene name relE Uniprot ID A0A1H9NMR5
Locus tag O165_RS18375 Protein ID WP_023629498.1
Coordinates 3991381..3991671 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A2L0LWH9
Locus tag O165_RS18370 Protein ID WP_023629499.1
Coordinates 3991152..3991391 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O165_RS18355 3986449..3986967 - 519 WP_023632629.1 histidine phosphatase family protein -
O165_RS18360 3987032..3989335 - 2304 WP_038706802.1 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase -
O165_RS18365 3989573..3991060 + 1488 WP_038706803.1 methylenetetrahydrofolate reductase C-terminal domain-containing protein -
O165_RS18370 3991152..3991391 + 240 WP_023629499.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
O165_RS18375 3991381..3991671 + 291 WP_023629498.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
O165_RS18380 3991955..3992188 + 234 WP_031314705.1 Phd-YefM -
O165_RS30255 3992215..3992367 - 153 WP_158659585.1 hypothetical protein -
O165_RS18390 3992422..3993630 - 1209 WP_052062227.1 PAS domain-containing sensor histidine kinase -
O165_RS18395 3993623..3994435 - 813 WP_023629159.1 alpha/beta hydrolase -
O165_RS18400 3995805..3996401 + 597 WP_038706804.1 lipoprotein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11378.22 Da        Isoelectric Point: 10.2588

>T48825 WP_023629498.1 NZ_CP009365:3991381-3991671 [Pseudomonas soli]
MTYNLDFDARALKEWQKLGDTIRQQLKKKLATVLLNPRVEANRLHGFPDCYKIKLRSSGYRLVYQVIDHQIVVFVVAVDK
RERDQVYRKAAERLTE

Download         Length: 291 bp

>T48825 NZ_CP009365:3991381-3991671 [Pseudomonas soli]
ATGACCTATAACCTCGATTTCGATGCGCGCGCACTCAAGGAATGGCAGAAGCTCGGCGACACCATTCGCCAACAGCTAAA
GAAGAAGCTGGCAACCGTGTTGCTCAACCCGAGGGTCGAAGCGAACCGTCTGCACGGTTTCCCGGACTGCTACAAGATCA
AGCTGCGCAGCAGCGGATATCGATTGGTCTATCAGGTCATCGATCATCAAATCGTGGTGTTTGTGGTCGCCGTGGATAAA
CGTGAGCGAGATCAGGTTTACCGCAAGGCGGCCGAACGATTGACCGAGTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9050.45 Da        Isoelectric Point: 4.8146

>AT48825 WP_023629499.1 NZ_CP009365:3991152-3991391 [Pseudomonas soli]
MASINVRIDDDLKVRAYRELEKLGVTPSELMRQALQYVAERGQLPFKPVLLTEEDEALLATVRERLASPQRVRVTLDDL

Download         Length: 240 bp

>AT48825 NZ_CP009365:3991152-3991391 [Pseudomonas soli]
ATGGCGTCCATCAATGTACGTATCGACGACGACCTCAAGGTGCGCGCCTACCGTGAGCTGGAAAAGCTGGGTGTAACCCC
CTCCGAGCTGATGCGCCAAGCGCTGCAATATGTTGCTGAGCGCGGGCAACTGCCTTTTAAACCCGTGTTACTGACCGAAG
AGGACGAAGCACTGCTCGCCACGGTACGCGAACGCCTGGCCTCGCCGCAGAGGGTGAGGGTAACGCTGGATGACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1H9NMR5

Antitoxin

Source ID Structure
AlphaFold DB A0A2L0LWH9

References