Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2553459..2554131 Replicon chromosome
Accession NZ_CP009364
Organism Yersinia frederiksenii Y225

Toxin (Protein)


Gene name cptA Uniprot ID A0A386HHD1
Locus tag AW19_RS11990 Protein ID WP_038631074.1
Coordinates 2553459..2553884 (-) Length 142 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A386HHJ6
Locus tag AW19_RS11995 Protein ID WP_038631072.1
Coordinates 2553865..2554131 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AW19_RS11970 2549217..2549735 + 519 WP_038631082.1 flavodoxin FldB -
AW19_RS11975 2549809..2551230 - 1422 WP_038631080.1 cell envelope integrity protein CreD -
AW19_RS11980 2551323..2552750 - 1428 WP_038631078.1 two-component system sensor histidine kinase CreC -
AW19_RS11985 2552761..2553459 - 699 WP_038631076.1 two-component system response regulator CreB -
AW19_RS11990 2553459..2553884 - 426 WP_038631074.1 protein YgfX Toxin
AW19_RS11995 2553865..2554131 - 267 WP_038631072.1 FAD assembly factor SdhE Antitoxin
AW19_RS12000 2554397..2555389 + 993 WP_038631070.1 tRNA-modifying protein YgfZ -
AW19_RS12005 2555438..2556121 - 684 WP_038631068.1 hemolysin III family protein -
AW19_RS12010 2556376..2556978 + 603 WP_038631066.1 HD domain-containing protein -
AW19_RS12015 2556991..2557740 - 750 WP_038631064.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-77)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 16459.32 Da        Isoelectric Point: 10.1175

>T48820 WP_038631074.1 NZ_CP009364:c2553884-2553459 [Yersinia frederiksenii Y225]
VAQWRCDLRVSWHTQLFSLLAHGVLVILTLVAPWPQGYTALWLVLLTLVVFECIRSQKNIKSCQGEIRLKPGNVVLWKRH
EWVVVKQPWITRYGVLLSLQQTSNRSTRKRLWLAADSMPEEEWRQLCLLLRHSFGSDEGIN

Download         Length: 426 bp

>T48820 NZ_CP009364:c2553884-2553459 [Yersinia frederiksenii Y225]
GTGGCCCAGTGGCGATGTGACCTGCGGGTATCCTGGCACACTCAACTCTTCTCCTTATTAGCGCATGGCGTTTTGGTGAT
ACTTACATTGGTTGCGCCTTGGCCTCAGGGCTATACCGCACTGTGGTTAGTATTACTGACGCTGGTGGTGTTTGAGTGTA
TCCGCAGCCAGAAAAACATTAAGTCTTGTCAGGGCGAGATCAGGCTGAAACCCGGTAATGTGGTGCTCTGGAAAAGGCAT
GAATGGGTGGTCGTTAAACAGCCTTGGATCACTCGCTATGGCGTGTTATTGAGTTTACAACAGACAAGCAACCGCTCAAC
CCGTAAGCGTTTATGGTTGGCTGCTGACAGTATGCCAGAAGAGGAATGGCGGCAATTATGTCTGCTGTTGCGTCATTCGT
TTGGCTCGGATGAGGGCATTAATTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10503.06 Da        Isoelectric Point: 5.1405

>AT48820 WP_038631072.1 NZ_CP009364:c2554131-2553865 [Yersinia frederiksenii Y225]
MEIDNKARIHWACRRGMRELDISIMPFFEHEYDGLSDNEKQVFIRLLECDDPDLFNWLMNHGEPQDSELRQMVKLIQIRN
KARGPVAM

Download         Length: 267 bp

>AT48820 NZ_CP009364:c2554131-2553865 [Yersinia frederiksenii Y225]
ATGGAAATCGATAATAAAGCCCGCATTCACTGGGCATGCCGTCGGGGTATGCGTGAACTGGATATCTCTATCATGCCATT
TTTCGAACATGAATATGATGGCTTGAGTGACAACGAAAAGCAGGTTTTTATTCGTTTACTTGAATGTGATGATCCAGACT
TATTTAACTGGCTGATGAATCACGGGGAGCCGCAGGATAGCGAGCTGCGCCAAATGGTCAAACTGATTCAAATACGAAAT
AAAGCCCGTGGCCCAGTGGCGATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References